Compound Summary
Compound Information
diacylglycerol kinase inhibitor ii
Compound Name: | diacylglycerol kinase inhibitor ii |
Compound CID: | 657356 |
Synonyms: | diacylglycerol kinase inhibitor ii 120166-69-0 R59949 R 59949 R-59949 More... |
Iupac Name: | 3-[2-[4-[bis(4-fluorophenyl)methylidene]piperidin-1-yl]ethyl]-2-sulfanylidene-1H-quinazolin-4-one |
InChI: | InChI=1S/C28H25F2N3OS/c29-22-9-5-19(6-10-22)26(20-7-11-23(30)12-8-20)21-13-15-32(16-14-21)17-18-33-27(34)24-3-1-2-4-25(24)31-28(33)35/h1-12H,13-18H2,(H,31,35) |
InChIKey: | ZCNBZFRECRPCKU-UHFFFAOYSA-N |
Canonical Smiles: | C1CN(CCC1=C(C2=CC=C(C=C2)F)C3=CC=C(C=C3)F)CCN4C(=O)C5=CC=CC=C5NC4=S |
Isomeric Smiles: | C1CN(CCC1=C(C2=CC=C(C=C2)F)C3=CC=C(C=C3)F)CCN4C(=O)C5=CC=CC=C5NC4=S |
Molecular Weight: | 489.6 |
Molecular Formula: | C28H25F2N3OS |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
diacylglycerol kinase inhibitor ii
Molecular Weight: | 489.6 |
Molecular Formula: | C28H25F2N3OS |
Hydrogen Bond Donor Count: | 1 |
Hydrogen Bond Acceptor Count: | 5 |
Rotatable Bond Count: | 5 |
Heavy Atom Count: | 35 |
Complexity: | 770 |
Synonyms
diacylglycerol kinase inhibitor ii
| diacylglycerol kinase inhibitor ii | diacylglycerol kinase inhibitor ii |
|---|---|
diacylglycerol kinase inhibitor ii |
120166-69-0 |
R59949 |
R 59949 |
R-59949 |
R 59 949 |
MLS000069510 |
3-(2-(4-(bis(4-fluorophenyl)methylene)piperidin-1-yl)ethyl)-2-thioxo-2,3-dihydroquinazolin-4(1H)-one |
SMR000058550 |
3-2-4-bis(4-fluorophenyl)methylidenepiperidin-1-ylethyl-2-sulfanylidene-1H-quinazolin-4-one |
DAG Kinase Inhibitor II |
3-(2-(4-(Bis(4-fluorophenyl)methylene)-1-piperdinyl)ethyl)-2,3-dihydro-2-thioxo-4(1H)-quinazolinone |
SCHEMBL317664 |
CHEMBL261131 |
cid_657356 |
GTPL5957 |
STO500 |
BDBM43868 |
DTXSID70152707 |
CHEBI:109551 |
HMS2232E20 |
HMS3229C17 |
HMS3369C17 |
HMS3674M07 |
HSCI1_000348 |
MFCD00069258 |
ZINC25782729 |
AT22446 |
CCG-206745 |
NCGC00018133-01 |
NCGC00018133-02 |
NCGC00018133-03 |
3-2-4-(bis(4-Fluorophenyl)methylene)-1-piperidinylethyl-2,3-dihydro-2-thioxo-4(1H)-quinazolinone |
3-{2-4-bis-(4-Fluorophenyl)methylene-1-piperidinylethyl}-2,3-dihydro-2-thioxo-4(1H)quinazolinone |
Diacylglycerol Kinase Inhibitor II, solid |
FT-0759122 |
J-004272 |
R-59-949 |
BRD-K31273080-001-01-2 |
Q27077044 |
Diacylglycerol Kinase Inhibitor II - CAS 120166-69-0 |
3-2-4-bis(4-fluorophenyl)methylenepiperidinoethyl-2-thioxo-1H-quinazolin-4-one |
3-(2-{4-bis(4-fluorophenyl)methylidenepiperidin-1-yl}ethyl)-2-sulfanylidene-1,2,3,4-tetrahydroquinazolin-4-one |
3-2-(4-bis-(4-fluorophenyl)methylene-1-piperidinyl)ethyl -2,3-dihydro-2-thioxo-4(1h)quinazolinone |
3-2-4-bis(4-fluorophenyl)methylidene-1-piperidinylethyl-2-sulfanylidene-1H-quinazolin-4-one |
4(1H)-Quinazolinone,3-2-4-bis(4-fluorophenyl)methylene-1-piperidinylethyl-2,3-dihydro-2-thioxo- |
Experimental Data
diacylglycerol kinase inhibitor ii
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33 | umol/L | 16 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
diacylglycerol kinase inhibitor ii
Statistics Data
diacylglycerol kinase inhibitor ii
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 16 | 1 | 1 |
Statistics Data Visualization
diacylglycerol kinase inhibitor ii
