Compound Summary
Compound Information
(Z)-Gugglesterone
Compound Name: | (Z)-Gugglesterone |
Compound CID: | 6510278 |
Synonyms: | (Z)-Gugglesterone trans-4,17(20)-Pregnadiene-3,16-dione GS, trans- (17Z)-Guggulsterone Pregna-4,17(20)-diene-3,16-dione, (17Z)- More... |
Iupac Name: | (10R,13S,17Z)-17-ethylidene-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15-decahydrocyclopenta[a]phenanthrene-3,16-dione |
InChI: | InChI=1S/C21H28O2/c1-4-16-19(23)12-18-15-6-5-13-11-14(22)7-9-20(13,2)17(15)8-10-21(16,18)3/h4,11,15,17-18H,5-10,12H2,1-3H3/b16-4+/t15?,17?,18?,20-,21+/m0/s1 |
InChIKey: | WDXRGPWQVHZTQJ-XCTJHIRPSA-N |
Canonical Smiles: | CC=C1C(=O)CC2C1(CCC3C2CCC4=CC(=O)CCC34C)C |
Isomeric Smiles: | C/C=C/1\C(=O)CC2[C@@]1(CCC3C2CCC4=CC(=O)CC[C@]34C)C |
Molecular Weight: | 312.4 |
Molecular Formula: | C21H28O2 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
(Z)-Gugglesterone
Molecular Weight: | 312.4 |
Molecular Formula: | C21H28O2 |
Hydrogen Bond Donor Count: | 0 |
Hydrogen Bond Acceptor Count: | 2 |
Rotatable Bond Count: | 0 |
Heavy Atom Count: | 23 |
Complexity: | 640 |
Synonyms
(Z)-Gugglesterone
| (Z)-Gugglesterone | (Z)-Gugglesterone |
|---|---|
(Z)-Gugglesterone |
trans-4,17(20)-Pregnadiene-3,16-dione |
GS, trans- |
(17Z)-Guggulsterone |
Pregna-4,17(20)-diene-3,16-dione, (17Z)- |
Lopac0_000433 |
SCHEMBL258031 |
CHEMBL372106 |
SCHEMBL12858540 |
CCG-204525 |
4,17(20)-cis-Pregnadiene-3,6-dione |
NCGC00093854-01 |
NCGC00093854-02 |
NCGC00093854-03 |
EU-0100433 |
G 5168 |
SR-01000075837 |
SR-01000075837-1 |
Experimental Data
(Z)-Gugglesterone
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33 | umol/L | 9 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
(Z)-Gugglesterone
Statistics Data
(Z)-Gugglesterone
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 9 | 1 | 1 |
Statistics Data Visualization
(Z)-Gugglesterone
