Compound Summary


  Compound Information
 Mevastatin

Compound Name:

Mevastatin

Compound CID:

64715

Synonyms:

Mevastatin

compactin

73573-88-3

ML-236B

Mevastatina

More...

Iupac Name:

[(1S,7S,8S,8aR)-8-[2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl]-7-methyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl] (2S)-2-methylbutanoate

InChI:

InChI=1S/C23H34O5/c1-4-14(2)23(26)28-20-7-5-6-16-9-8-15(3)19(22(16)20)11-10-18-12-17(24)13-21(25)27-18/h6,8-9,14-15,17-20,22,24H,4-5,7,10-13H2,1-3H3/t14-,15-,17+,18+,19-,20-,22-/m0/s1

InChIKey:

AJLFOPYRIVGYMJ-INTXDZFKSA-N

Canonical Smiles:

CCC(C)C(=O)OC1CCC=C2C1C(C(C=C2)C)CCC3CC(CC(=O)O3)O

Isomeric Smiles:

CC[C@H](C)C(=O)O[C@H]1CCC=C2[C@H]1[C@H]([C@H](C=C2)C)CC[C@@H]3C[C@H](CC(=O)O3)O

Molecular Weight:

390.5

Molecular Formula:

C23H34O5

  Compound Structure
 2D Structure:
 3D Structure:
  Computed Properties
 Mevastatin

Molecular Weight:

390.5

Molecular Formula:

C23H34O5

Hydrogen Bond Donor Count:

1

Hydrogen Bond Acceptor Count:

5

Rotatable Bond Count:

7

Heavy Atom Count:

28

Complexity:

637

  Synonyms
 Mevastatin

Mevastatin Mevastatin

Mevastatin

compactin

73573-88-3

ML-236B

Mevastatina

Mevastatine

Mevastatinum

Mevastatinum INN-Latin

Antibiotic ML 236B

CS 500

UNII-1UQM1K0W9X

ML 236 B

1UQM1K0W9X

CHEMBL54440

(1S,7S,8S,8aR)-8-2-(2R,4R)-4-hydroxy-6-oxooxan-2-ylethyl-7-methyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl (2S)-2-methylbutanoate

CHEBI:34848

MFCD05662341

ML236B

Mevastatin INN

Compactin (penicillium)

Mevastatine INN-French

Mevastatina INN-Spanish

(S)-((1S,7S,8S,8aR)-8-(2-((2R,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl)ethyl)-7-methyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl) 2-methylbutanoate

Butanoic acid, 2-methyl-, (1S,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro-7-methyl-8-2-(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-ylethyl-1-naphthalenyl ester, (2S)-

SMR000336944

CCRIS 4505

kompaktin

NCGC00095942-01

Mevastatin- Bio-X

EC 700-442-0

SCHEMBL1116

DSSTox_CID_20684

DSSTox_RID_79540

DSSTox_GSID_40684

Lopac0_000754

MLS000721804

MLS000759452

MLS001424284

MLS002207227

GTPL3031

DTXSID4040684

Mevastatin, >=96% (HPLC)

HMS2052P07

HMS2089D10

HMS2232N09

HMS3262G10

HMS3268A19

HMS3412H15

HMS3676H15

HMS3713B06

ZINC3833876

Tox21_111540

Tox21_500754

BDBM50011036

CS-500

NSC779705

s4223

AKOS015994712

Mevastatin, >=95% (HPLC), powder

CCG-101174

CS-1234

DB06693

KS-1085

LP00754

NC00424

NSC 759322

NSC-779705

SDCCGSBI-0050732.P002

7-(1,2,6,7,8,8a-Hexahydro-2-methyl-8-(2-methylbutyryloxy)naphthyl)-3-hydroxyheptan-5-olide

SMP1_000077

NCGC00025202-04

NCGC00261439-01

(1S,7S,8S,8aR)-8-(2-((2R,4R)-4-Hydroxy-6-oxotetrahydro-2H-pyran-2-yl)ethyl)-7-methyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl(2S)-2-methylbutanoate

BM164666

Butanoic acid, 2-methyl-, (1S,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro-7-methyl-8-(2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl)-1-naphthalenyl ester, (2S)-

Butanoic acid, 2-methyl-, 1,2,3,7,8,8a-hexahydro-7-methyl-8-(2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl)-1-naphthalenyl ester, (1S-(1-alpha(R*),7-beta,8-beta(2S*,4S*),8a-beta))-

HY-17408

I518

Mevastatin 100 microg/mL in Acetonitrile

AB0013739

CAS-73573-88-3

B1788

EU-0100754

M2275

H11997

M 2537

AB00588266-06

AB00588266-08

AB00588266_09

573M883

A837861

Q414407

SR-01000729493

L-637312

SR-01000729493-4

BRD-K94441233-001-03-1

BRD-K94441233-001-17-1

(1S,7S,8S,8aR)-8-(2-((2R,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl)ethyl)-7-methyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl (S)-2-methylbutanoate

(1S,7S,8S,8aR)-8-{2-(2R,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-ylethyl}-7-methyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl (2S)-2-methylbutanoate

(S)-((1S,7S,8S,8aR)-8-(2-((2R,4R)-4-hydroxy-6-oxo-tetrahydro-2H-pyran-2-yl)ethyl)-7-methyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl) 2-methylbutanoate

(S)-2-Methyl-butyric acid (1S,7S,8S,8aR)-8-2-((2R,4R)-4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl-7-methyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester

2-Methyl-butyric acid 8-2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl-7-methyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester

2-Methyl-butyric acid 8-2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl-7-methyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester((+)-compactin)

2-Methyl-butyric acid 8-2-(4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl-7-methyl-1,2,3,7,8,8a-hexahydro-naphthalen-1-yl ester(compactin)

  Experimental Data
 Mevastatin

Species Dosage Unit CG Lifespan(AVG/MED days) TG Lifespan(AVG/MED days) Lifespan Change(AVG/MED%) CG Lifespan(MAX days) TG Lifespan(MAX days) Lifespan Change(MAX%) Significant Strain Gender PubMed Active Label
Caenorhabditis elegans 33 umol/L -2 NS N2 24134630 Inactive
  Experimental Data Visualization
 Mevastatin

  Statistics Data
 Mevastatin

Species Lifespan Change(AVG/MED%) Lifespan Change(MAX%) Count Reference Count Data point
Caenorhabditis elegans -2 1 1
  Statistics Data Visualization
 Mevastatin