Compound Summary
Compound Information
Flupirtine maleate
Compound Name: | Flupirtine maleate |
Compound CID: | 6435335 |
Synonyms: | Flupirtine maleate 75507-68-5 Katadolon Flupirtine Maleate Salt Flupirtine (Maleate) More... |
Iupac Name: | (Z)-but-2-enedioic acid;ethyl N-[2-amino-6-[(4-fluorophenyl)methylamino]pyridin-3-yl]carbamate |
InChI: | InChI=1S/C15H17FN4O2.C4H4O4/c1-2-22-15(21)19-12-7-8-13(20-14(12)17)18-9-10-3-5-11(16)6-4-10;5-3(6)1-2-4(7)8/h3-8H,2,9H2,1H3,(H,19,21)(H3,17,18,20);1-2H,(H,5,6)(H,7,8)/b;2-1- |
InChIKey: | DPYIXBFZUMCMJM-BTJKTKAUSA-N |
Canonical Smiles: | CCOC(=O)NC1=C(N=C(C=C1)NCC2=CC=C(C=C2)F)N.C(=CC(=O)O)C(=O)O |
Isomeric Smiles: | CCOC(=O)NC1=C(N=C(C=C1)NCC2=CC=C(C=C2)F)N.C(=C\C(=O)O)\C(=O)O |
Molecular Weight: | 420.4 |
Molecular Formula: | C19H21FN4O6 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
Flupirtine maleate
Molecular Weight: | 420.4 |
Molecular Formula: | C19H21FN4O6 |
Hydrogen Bond Donor Count: | 5 |
Hydrogen Bond Acceptor Count: | 10 |
Rotatable Bond Count: | 8 |
Heavy Atom Count: | 30 |
Complexity: | 469 |
Synonyms
Flupirtine maleate
| Flupirtine maleate | Flupirtine maleate |
|---|---|
Flupirtine maleate |
75507-68-5 |
Katadolon |
Flupirtine Maleate Salt |
Flupirtine (Maleate) |
UNII-0VCI53PK4A |
Flupirtine maleate USAN |
75507-68-5 (maleate). |
0VCI53PK4A |
D-9998 |
ETHYL (2-AMINO-6-((4-FLUOROBENZYL)AMINO)PYRIDIN-3-YL)CARBAMATE MALEATE |
W-2964M |
NCGC00093935-01 |
Flupirtine maleate (USAN) |
DSSTox_CID_25771 |
DSSTox_RID_81113 |
DSSTox_GSID_45771 |
D 9998 |
Flupirtin-maleat |
Flupirtin-maleat German |
C19H21FN4O6 |
(Z)-but-2-enedioic acid;ethyl N-2-amino-6-(4-fluorophenyl)methylaminopyridin-3-ylcarbamate |
Carbamic acid, (2-amino-6-(((4-fluorophenyl)methyl)amino)-3-pyridinyl)-, ethyl ester, (Z)-2-butenedioate (1:1) |
CAS-75507-68-5 |
W 2964M |
NCGC00015451-03 |
EINECS 278-225-0 |
Flupirtinmaleat |
Effirma |
Katadolon maleate |
Carbamic acid, 2-amino-6-(4-fluorophenyl)methylamino-3-pyridinyl-, ethyl ester, (Z)-2-butenedioate (1:1) |
Flupirtine maleate- Bio-X |
2-Amino-3-(ethoxycarbonylamino)-6-(4-fluorobenzylamino)pyridine Maleate Salt |
Ethyl 2-amino-6-((p-fluorobenzyl)amino)-3-pyridinecarbamate maleate (1:1) |
Ethyl-N-(2-amino-6-(4-fluorophenylmethylamino)pyridin-3-yl)carbamate maleate |
(2-Amino-6-(((4-fluorophenyl)methyl)amino)-3-pyridinyl)carbamic acid ethyl ester maleate |
Ethyl-N-(2-amino-6-(4-fluor-phenylmethylamino)pyridin-3-yl)carbamat maleat German |
SCHEMBL124707 |
CHEMBL1256752 |
DTXSID8045771 |
HMS3261N15 |
DIETHYL4-FLUOROPHENYLMALONATE |
Tox21_111232 |
Tox21_113397 |
Tox21_500547 |
AC-454 |
MFCD00941415 |
AKOS024286722 |
Ethyl-N-(2-amino-6-(4-fluor-phenylmethylamino)pyridin-3-yl)carbamat maleat |
Tox21_111232_1 |
BCP9000699 |
CCG-221851 |
CS-0573 |
LP00547 |
2-AMINO-6-(4-FLUORO-BENZYLAMINO)-PYRIDIN-3-YL-CARBAMIC ACID ETHYL ESTER MALEATE |
Ethyl 2-amino-6-((4-fluorobenzyl)amino)pyridine-3-carbamate, compound with maleic acid (1:1) |
NCGC00015451-05 |
NCGC00093935-02 |
NCGC00261232-01 |
133AP001 |
BF164473 |
HY-17001 |
ST096085 |
Flupirtine maleate salt, >=98% (HPLC) |
EU-0100547 |
F0736 |
D04226 |
F 8927 |
J10053 |
507F685 |
A838439 |
SR-01000075887 |
Q-101869 |
SR-01000075887-1 |
Q27231153 |
2-amino-6-(4-fluorophenyl)methylamino-3-pyridinyl-carbamic acid, ethyl ester maleate |
N-2-Amino-6-4-fluorophenyl)methylamino-3-pyridinylcarbamic acid ethyl ester maleate |
(Z)-but-2-enedioic acid; ethyl N-2-azanyl-6-(4-fluorophenyl)methylaminopyridin-3-ylcarbamate |
N-(2-amino-6-{(4-fluorophenyl)methylamino}(3-pyridyl))ethoxycarboxamide, (2Z )but-2-enedioic acid |
N-2-amino-6-(4-fluorophenyl)methylamino-3-pyridinylcarbamic acid ethyl ester; (Z)-2-butenedioic acid |
Experimental Data
Flupirtine maleate
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33 | umol/L | 5 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
Flupirtine maleate
Statistics Data
Flupirtine maleate
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 5 | 1 | 1 |
Statistics Data Visualization
Flupirtine maleate
