Compound Summary
Compound Information
(+)-MK 801 Maleate
Compound Name: | (+)-MK 801 Maleate |
Compound CID: | 6420042 |
Synonyms: | (+)-MK 801 Maleate DIZOCILPINE MALEATE (+)-MK-801 hydrogen maleate 77086-22-7 Dizocilpine hydrogen maleate More... |
Iupac Name: | (Z)-but-2-enedioic acid;(1S,9R)-1-methyl-16-azatetracyclo[7.6.1.02,7.010,15]hexadeca-2,4,6,10,12,14-hexaene |
InChI: | InChI=1S/C16H15N.C4H4O4/c1-16-13-8-4-2-6-11(13)10-15(17-16)12-7-3-5-9-14(12)16;5-3(6)1-2-4(7)8/h2-9,15,17H,10H2,1H3;1-2H,(H,5,6)(H,7,8)/b;2-1-/t15-,16+;/m1./s1 |
InChIKey: | QLTXKCWMEZIHBJ-PJGJYSAQSA-N |
Canonical Smiles: | CC12C3=CC=CC=C3CC(N1)C4=CC=CC=C24.C(=CC(=O)O)C(=O)O |
Isomeric Smiles: | C[C@@]12C3=CC=CC=C3C[C@@H](N1)C4=CC=CC=C24.C(=C\C(=O)O)\C(=O)O |
Molecular Weight: | 337.4 |
Molecular Formula: | C20H19NO4 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
(+)-MK 801 Maleate
Molecular Weight: | 337.4 |
Molecular Formula: | C20H19NO4 |
Hydrogen Bond Donor Count: | 3 |
Hydrogen Bond Acceptor Count: | 5 |
Rotatable Bond Count: | 2 |
Heavy Atom Count: | 25 |
Complexity: | 432 |
Synonyms
(+)-MK 801 Maleate
| (+)-MK 801 Maleate | (+)-MK 801 Maleate |
|---|---|
(+)-MK 801 Maleate |
DIZOCILPINE MALEATE |
(+)-MK-801 hydrogen maleate |
77086-22-7 |
Dizocilpine hydrogen maleate |
UNII-6LR8C1B66Q |
(+)-MK 801 (Maleate) |
Dizocilpine maleate USAN |
6LR8C1B66Q |
Dizocilpine (Maleate) |
Dizocilpine maleate (USAN) |
DSSTox_CID_25785 |
DSSTox_RID_81126 |
DSSTox_GSID_45785 |
C16H15N.C4H4O4 |
(-)-MK 801 Maleate |
SR-01000075457 |
NCGC00094136-01 |
121917-57-5 |
Dizocilipine maleate |
Prestwick_903 |
EINECS 278-614-5 |
(+)-MK801 |
(+)MK-801 maleate |
MLS000860084 |
SCHEMBL122777 |
CHEMBL344151 |
DTXSID2045785 |
AOB1436 |
EX-A566 |
(+)-10,11-Dihydro-5-methyl-5H-dibenzo(a,d)cyclohepten-5,10-diyldiammonium maleate |
(5S,10R)-5-methyl-10,11-dihydro-5H-5,10-epiminodibenzoa,d7annulene maleate |
CHEBI:176788 |
HMS1568E20 |
HMS2095E20 |
HMS2230A11 |
HMS3262P05 |
HMS3411H14 |
HMS3675H14 |
HMS3712E20 |
HMS3884B22 |
(+/-)-mk-801 hydrogen maleate |
BCP21811 |
Tox21_111251 |
Tox21_113059 |
Tox21_500872 |
2829AH |
MFCD00082465 |
s2876 |
AKOS024458698 |
BCP9000949 |
CCG-220109 |
CCG-222176 |
CS-1290 |
LP00872 |
(+)-10,11-Dihydro-5-methyl-5H-dibenzo(a,d)cyclohepten-5,10-imine maleate (1:1) |
(+)-MK-801 hydrogen maleate, powder |
NCGC00094196-01 |
NCGC00261557-01 |
AS-16649 |
BM162595 |
HY-15084 |
SMR000326942 |
EU-0100872 |
M-107 |
D03878 |
SR-01000597866 |
SR-01000075457-1 |
SR-01000075457-4 |
SR-01000075457-5 |
SR-01000597866-1 |
Q27265120 |
(5S,10R)-(+)-5-Methyl-10,11-dihydro-5H-dibenzoa,dcyclohepten-5,10-imine maleate |
(5S,10R)-5-methyl-10,11-dihydro-5H-5,10-epiminodibenzoa,d7annulene (2Z)-but-2-enedioate |
5H-Dibenzo(a,d)cyclohepten-5,10-imine, 10,11-dihydro-5-methyl-, (+)-, (Z)-2-butenedioate (1:1) |
Experimental Data
(+)-MK 801 Maleate
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33 | umol/L | -5 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
(+)-MK 801 Maleate
Statistics Data
(+)-MK 801 Maleate
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | -5 | 1 | 1 |
Statistics Data Visualization
(+)-MK 801 Maleate
