Compound Summary
Compound Information
Telenzepine dihydrochloride
Compound Name: | Telenzepine dihydrochloride |
Compound CID: | 6419995 |
Synonyms: | Telenzepine dihydrochloride 147416-96-4 Telenzepine (Dihydrochloride) Telenzepine hydrochloride 1-methyl-10-2-(4-methylpiperazin-1-yl)acetyl-5H-thieno3,4-b1,5benzodiazepin-4-one;dihydrochloride More... |
Iupac Name: | 1-methyl-10-[2-(4-methylpiperazin-1-yl)acetyl]-5H-thieno[3,4-b][1,5]benzodiazepin-4-one;dihydrochloride |
InChI: | InChI=1S/C19H22N4O2S.2ClH/c1-13-18-14(12-26-13)19(25)20-15-5-3-4-6-16(15)23(18)17(24)11-22-9-7-21(2)8-10-22;;/h3-6,12H,7-11H2,1-2H3,(H,20,25);2*1H |
InChIKey: | JTQJFSQQHGPLOX-UHFFFAOYSA-N |
Canonical Smiles: | CC1=C2C(=CS1)C(=O)NC3=CC=CC=C3N2C(=O)CN4CCN(CC4)C.Cl.Cl |
Isomeric Smiles: | CC1=C2C(=CS1)C(=O)NC3=CC=CC=C3N2C(=O)CN4CCN(CC4)C.Cl.Cl |
Molecular Weight: | 443.4 |
Molecular Formula: | C19H24Cl2N4O2S |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
Telenzepine dihydrochloride
Molecular Weight: | 443.4 |
Molecular Formula: | C19H24Cl2N4O2S |
Hydrogen Bond Donor Count: | 3 |
Hydrogen Bond Acceptor Count: | 5 |
Rotatable Bond Count: | 2 |
Heavy Atom Count: | 28 |
Complexity: | 552 |
Synonyms
Telenzepine dihydrochloride
| Telenzepine dihydrochloride | Telenzepine dihydrochloride |
|---|---|
Telenzepine dihydrochloride |
147416-96-4 |
Telenzepine (Dihydrochloride) |
Telenzepine hydrochloride |
1-methyl-10-2-(4-methylpiperazin-1-yl)acetyl-5H-thieno3,4-b1,5benzodiazepin-4-one;dihydrochloride |
10H-Thieno3,4-b1,5benzodiazepin-10-one, 4,9-dihydro-3-methyl-4-(4-methyl-1-piperazinyl)acetyl-, dihydrochloride (9CI) |
10H-Thieno3,4-b1,5benzodiazepin-10-one, 4,9-dihydro-3-methyl-4-2-(4-methyl-1-piperazinyl)acetyl-, hydrochloride (1:2) |
Telenzepine dihydrochloride hydrate |
SR-01000075349 |
Prestwick_649 |
SCHEMBL184401 |
CHEMBL1257109 |
DTXSID10423564 |
HMS1568N08 |
Tox21_501204 |
SK-871 |
AKOS024456398 |
CCG-220303 |
CCG-222508 |
LP01204 |
NCGC00094451-01 |
NCGC00261889-01 |
4,9-Dihydro-3-methyl-4-(4-methyl-1- |
B6606 |
EU-0101204 |
FT-0759736 |
T-122 |
B-803-32 |
B-818-03 |
B-818-04 |
J-008354 |
SR-01000075349-1 |
SR-01000075349-3 |
SR-01000075349-6 |
piperazinyl)acetyl-10H-thieno3,4-b1,5benzodiazepin-10-one dihydrochloride |
3-Methyl-4-(2-(4-Methylpiperazin-1-yl)acetyl)-4H-benzobthieno3,4-e1,4diazepin-10(9H)-one dihydrochloride |
4,9-Dihydro-3-methyl-4-(4-methyl-1-piperazinyl)acetyl-10H-thieno3,4-b1,5benzodiazepin-10-one dihydrochloride |
Experimental Data
Telenzepine dihydrochloride
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33 | umol/L | -6 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
Telenzepine dihydrochloride
Statistics Data
Telenzepine dihydrochloride
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | -6 | 1 | 1 |
Statistics Data Visualization
Telenzepine dihydrochloride
