Compound Summary
Compound Information
Doxepin Hydrochloride
Compound Name: | Doxepin Hydrochloride |
Compound CID: | 6419921 |
Synonyms: | Doxepin Hydrochloride 1229-29-4 Doxepin HCl (e)-doxepin hydrochloride UNII-CU61C5RH24 More... |
Iupac Name: | (3E)-3-(6H-benzo[c][1]benzoxepin-11-ylidene)-N,N-dimethylpropan-1-amine;hydrochloride |
InChI: | InChI=1S/C19H21NO.ClH/c1-20(2)13-7-11-17-16-9-4-3-8-15(16)14-21-19-12-6-5-10-18(17)19;/h3-6,8-12H,7,13-14H2,1-2H3;1H/b17-11+; |
InChIKey: | MHNSPTUQQIYJOT-SJDTYFKWSA-N |
Canonical Smiles: | CN(C)CCC=C1C2=CC=CC=C2COC3=CC=CC=C31.Cl |
Isomeric Smiles: | CN(C)CC/C=C/1\C2=CC=CC=C2COC3=CC=CC=C31.Cl |
Molecular Weight: | 315.8 |
Molecular Formula: | C19H22ClNO |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
Doxepin Hydrochloride
Molecular Weight: | 315.8 |
Molecular Formula: | C19H22ClNO |
Hydrogen Bond Donor Count: | 1 |
Hydrogen Bond Acceptor Count: | 2 |
Rotatable Bond Count: | 3 |
Heavy Atom Count: | 22 |
Complexity: | 363 |
Synonyms
Doxepin Hydrochloride
| Doxepin Hydrochloride | Doxepin Hydrochloride |
|---|---|
Doxepin Hydrochloride |
1229-29-4 |
Doxepin HCl |
(e)-doxepin hydrochloride |
UNII-CU61C5RH24 |
Curatin |
Novoxapin |
Silenor |
Sinequan |
Adapin |
Aponal |
Toruan |
Doxepine hydrochloride |
Novoxapin hydrochloride |
Doxepin (Hydrochloride) |
MLS000069794 |
CU61C5RH24 |
MF 10 HCl |
4698-39-9 |
SMR000058230 |
Sinequan (TN) |
NSC-108160 |
C19H21NO.HCl |
DSSTox_CID_25145 |
DSSTox_RID_80701 |
DSSTox_GSID_45145 |
Quitaxon |
Sinequin |
P-3693A |
3-(Dibenzob,eoxepin-11(6H)-ylidene)-N,N-dimethylpropan-1-amine hydrochloride |
SR-01000075551 |
NCGC00015344-03 |
EINECS 214-966-8 |
CAS-1229-29-4 |
trans-Doxepin hydrochloride |
MFCD00079135 |
(3-(6H-dibenzoc,foxepin-11-ylidene)propyl)dimethylamine, chloride |
Doxepin hydrochloride (E)-isomer |
(3E)-3-(6H-benzoc1benzoxepin-11-ylidene)-N,N-dimethylpropan-1-amine;hydrochloride |
Doxepin hydrochloride USAN:USP |
Prestwick_187 |
Zonalon (TN) |
Opera_ID_675 |
1-Propanamine, 3-dibenz(b,e)oxepin-11(6H)ylidene-N,N-dimethyl-, hydrochloride |
11-(3-(Dimethylamino)propylidene)-6,11-dihydrodibenz(b,e)oxepin hydrochloride |
N,N-Dimethyldibenz(b,e)oxepin-delta(sup 11(6H),gamma)-propylamine hydrochloride |
Doxepin hydrochloride (USP) |
SCHEMBL60287 |
MLS001148235 |
MLS002207250 |
MLS002222181 |
MLS002548858 |
CHEBI:4711 |
CHEMBL1200462 |
DTXSID8045145 |
HMS1568F08 |
HY-B0725 |
Tox21_110130 |
Tox21_500339 |
s3120 |
SBB005916 |
11-(3-Dimethylaminopropylidene)-6,11-dihydrodibenzb,eoxepine hydrochloride |
AKOS015895087 |
Tox21_110130_1 |
CCG-220263 |
CCG-221643 |
KS-5094 |
LP00339 |
NC00447 |
Dibenz(b,e)oxepin-delta(sup 11(6H),gamma)-propylamine, N,N-dimethyl-, hydrochloride |
NCGC00024623-04 |
NCGC00093778-01 |
NCGC00093778-02 |
NCGC00261024-01 |
BD166235 |
ST025239 |
AB0109368 |
EU-0100339 |
D 4526 |
D00814 |
J10288 |
229D294 |
A804993 |
Q-201044 |
SR-01000075551-1 |
SR-01000075551-5 |
Q27275787 |
Doxepin Hydrochloride 1.0 mg/ml in Methanol (as free base) |
UNII-3U9A0FE9N5 component MHNSPTUQQIYJOT-SJDTYFKWSA-N |
Doxepin hydrochloride, European Pharmacopoeia (EP) Reference Standard |
Doxepin hydrochloride, United States Pharmacopeia (USP) Reference Standard |
(3E)-3-(6H-benzoc1benzoxepin-11-ylidene)-N,N-dimethyl-1-propanamine hydrochloride |
(3E)-3-(6H-benzoc1benzoxepin-11-ylidene)-N,N-dimethyl-propan-1-amine hydrochloride |
Dibenz(b,e)oxepin-delta11(6H),gamma-propylamine, N,N-dimethyl-, hydrochloride (8CI) |
Doxepin for system suitability, European Pharmacopoeia (EP) Reference Standard |
Doxepin hydrochloride, ~85% E-isomer basis, >=98% (GC), 15% Z-isomer basis, powder |
1-Propanamine, 3-dibenz(b,e)oxepin-11-(6H)-ylidene-N,N-dimethyl-dimethyl-, hydrochloride, (E)- |
Experimental Data
Doxepin Hydrochloride
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33 | umol/L | 15 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
Doxepin Hydrochloride
Statistics Data
Doxepin Hydrochloride
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 15 | 1 | 1 |
Statistics Data Visualization
Doxepin Hydrochloride
