Compound Summary
Compound Information
Verapamil hydrochloride
Compound Name: | Verapamil hydrochloride |
Compound CID: | 62969 |
Synonyms: | Verapamil hydrochloride 152-11-4 Verapamil HCl Manidon Cordilox More... |
Iupac Name: | 2-(3,4-dimethoxyphenyl)-5-[2-(3,4-dimethoxyphenyl)ethyl-methylamino]-2-propan-2-ylpentanenitrile;hydrochloride |
InChI: | InChI=1S/C27H38N2O4.ClH/c1-20(2)27(19-28,22-10-12-24(31-5)26(18-22)33-7)14-8-15-29(3)16-13-21-9-11-23(30-4)25(17-21)32-6;/h9-12,17-18,20H,8,13-16H2,1-7H3;1H |
InChIKey: | DOQPXTMNIUCOSY-UHFFFAOYSA-N |
Canonical Smiles: | CC(C)C(CCCN(C)CCC1=CC(=C(C=C1)OC)OC)(C#N)C2=CC(=C(C=C2)OC)OC.Cl |
Isomeric Smiles: | CC(C)C(CCCN(C)CCC1=CC(=C(C=C1)OC)OC)(C#N)C2=CC(=C(C=C2)OC)OC.Cl |
Molecular Weight: | 491.1 |
Molecular Formula: | C27H39ClN2O4 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
Verapamil hydrochloride
Molecular Weight: | 491.1 |
Molecular Formula: | C27H39ClN2O4 |
Hydrogen Bond Donor Count: | 1 |
Hydrogen Bond Acceptor Count: | 6 |
Rotatable Bond Count: | 13 |
Heavy Atom Count: | 34 |
Complexity: | 606 |
Synonyms
Verapamil hydrochloride
| Verapamil hydrochloride | Verapamil hydrochloride |
|---|---|
Verapamil hydrochloride |
152-11-4 |
Verapamil HCl |
Manidon |
Cordilox |
Calcan hydrochloride |
(+/-)-VERAPAMIL HYDROCHLORIDE |
Cardibeltin |
Verapamil (hydrochloride) |
23313-68-0 |
Cardiabeltin |
Cardioprotect |
Veroptinstada |
Berkatens |
Calaptin |
Cardiagutt |
Caveril |
Civicor |
Coraver |
Corpamil |
Dignover |
Durasoptin |
Geangin |
Harteze |
Hexasoptin |
Hormitol |
Ikapress |
Inselon |
Isoptino |
Izoptin |
Jenapamil |
Lodixal |
Magotiron |
Praecicor |
Robatelan |
Vasomil |
Vasopten |
Verabeta |
Veracor |
Verahexal |
Veraloc |
Veramex |
Veramil |
Verapin |
Verasal |
Verasifar |
Veratensin |
Verdilac |
Vetrimil |
Akilen |
Elthon |
Flamon |
Ikacor |
Quasar |
Univer |
Univex |
Vortac |
Anpec |
Calan |
Ormil |
Rapam |
Verapamil Ebewe |
Verapamil Riker |
Verapamil Verla |
Civicor Retard |
Isoptin Retard |
Manidon Retard |
Vera-Sanorania |
Verapamil Acis |
Verapamil Atid |
Novo-Veramil |
Verapamil Basics |
Verapamil Nordic |
Verapamil-AbZ |
Novapamyl LP |
Verapamil AL |
Verapamil NM |
Verapamil PB |
Verapamil SR |
Verapamyl hydrochloride |
Apo-Verap |
Cordilox SR |
Dilacoran HTA |
Veracaps SR |
Verapamil MSD |
Arpamyl LP |
Hexasoptin Retard |
Isoptin SR |
Nu-Verap |
Verapamil Henning |
Verelan SR |
Covera-HS |
Calan SR |
Verapamil Injection |
Verapamil NM Pharma |
Calaptin 240 SR |
Verapress 240 SR |
MFCD00055208 |
5-((3,4-dimethoxyphenethyl)(methyl)amino)-2-(3,4-dimethoxyphenyl)-2-isopropylpentanenitrile hydrochloride |
MLS000069485 |
NSC657799 |
NSC-272366 |
NSC-657799 |
SMR000059109 |
2-(3,4-dimethoxyphenyl)-5-{2-(3,4-dimethoxyphenyl)ethyl(methyl)amino}-2-(propan-2-yl)pentanenitrile hydrochloride |
5-N-(3,4-Dimethoxyphenylethyl)methylamino-2-(3,4-dimethoxyphenyl)-2-isopropylvaleronitrile hydrochloride |
( inverted exclamation markA)-Verapamil hydrochlorid |
Verapamil chloridrate |
D-365 hydrochloride |
Iproveratril hydrochloride |
2-(3,4-dimethoxyphenyl)-5-2-(3,4-dimethoxyphenyl)ethyl-methylamino-2-propan-2-ylpentanenitrile;hydrochloride |
2-(3,4-dimethoxyphenyl)-5-{2-(3,4-dimethoxyphenyl)ethylmethylamino}-2-(methy lethyl)pentanenitrile, chloride |
5-(3,4-Dimethoxyphenethyl)methylamino-2-(3,4-dimethoxy phenyl)-2-isopropylvaleronitrile hydrochloride |
NSC272366 |
SR-01000000050 |
EINECS 205-800-5 |
NSC 272366 |
LU 20175 |
C27H39ClN2O4 |
Covera |
C27H38N2O4.HCl |
(+/-)-Verapamil, Hydrochloride |
Verapamil, HCl |
Verapamil-d7 HCl |
Prestwick_440 |
Vasolan (TN) |
Verelan (TN) |
Covera-hs (TN) |
Calan (TN) |
Isotopin hydrochloride |
Verapamil Hydrochloride (Isoptin, Iproveratril, Calan) |
Verapamil hydrochloride USAN:USP:JAN |
Opera_ID_1210 |
()-Verapamil hydrochlorid |
CAS-152-11-4 |
(y)-Verapamil hydrochloride |
(?)-Verapamil hydrochloride |
CHEMBL1280 |
DSSTox_CID_14095 |
DSSTox_RID_79114 |
Verapamil Hydrochloride,(S) |
DSSTox_GSID_34095 |
SCHEMBL33296 |
5-((3,4-Dimethoxyphenethyl)methylamino)-2-(3,4-dimethoxyphenyl)-2-isopropylvaleronitrile monohydrochloride |
Benzeneacetonitrile, alpha-(3-((2-(3,4-dimethoxyphenyl)ethyl)methylamino)propyl)-3,4-dimethoxy-alpha-(1-methylethyl)-, monohydrochloride |
MLS001055442 |
MLS002222213 |
(+-)-Verapamil hydrochloride |
(??)-Verapamil hydrochloride |
ARONIS24174 |
SPECTRUM2300307 |
DTXSID2034095 |
HMS1568M04 |
HMS1922J16 |
Pharmakon1600-02300307 |
BCP06465 |
HY-A0064 |
Tox21_201180 |
Tox21_501237 |
CCG-39491 |
NSC759589 |
s4202 |
Verapamil hydrochloride (JP17/USP) |
AKOS005267117 |
AC-8483 |
CS-1685 |
LP01237 |
NSC-759589 |
NCGC00024710-03 |
NCGC00094479-01 |
NCGC00094479-02 |
NCGC00094479-03 |
NCGC00094479-04 |
NCGC00094479-05 |
NCGC00258732-01 |
NCGC00261922-01 |
(+-)-5-((3,4-Dimethoxyphenethyl)methylamino)-2-(3,4-dimethoxyphenyl)-2-isopropylvaleronitrile monohydrochloride |
2-(3,4-dimethoxyphenyl)-5-2-(3,4-dimethoxyphenyl)ethyl-methylamino-2-propan-2-ylpentanenitrile hydrochloride |
AC-16228 |
AS-16018 |
Benzeneacetonitrile, alpha-(3-((2-(3,4-dimethoxyphenyl)ethyl)methylamino)propyl)-3,4-dimethoxy-alpha-(1-methylethyl)-, monohydrochloride, (+-)- |
BV164516 |
LU-20175 |
R853 |
ST066908 |
SY073165 |
Valeronitrile, 5-((3,4-dimethoxyphenethyl)methylamino)-2-(3,4-dimethoxyphenyl)-2-isopropyl-, monohydrochloride |
AB0018370 |
EU-0101237 |
FT-0603360 |
FT-0630593 |
FT-0655647 |
FT-0675800 |
SW196662-4 |
D00619 |
D78147 |
D88195 |
V 4629 |
( inverted question mark)-Verapamil hydrochloride |
54236-EP2305219A1 |
54236-EP2308562A2 |
152V114 |
A816666 |
Q-201923 |
SR-01000000050-2 |
SR-01000000050-4 |
(+/-)-Verapamil, Hydrochloride - CAS 152-11-4 |
Q27291481 |
SR-01000000050-11 |
Z2210978706 |
(+/-)-Verapamil hydrochloride, >=99% (titration), powder |
Verapamil Hydrochloride 1.0 mg/ml in Methanol (as free base) |
Verapamil hydrochloride, European Pharmacopoeia (EP) Reference Standard |
Verapamil hydrochloride, United States Pharmacopeia (USP) Reference Standard |
(+/-)-Verapamil hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material |
2-(3,4-Dimethoxyphenyl)-5-2-(3,4-dimethoxyphenyl)-ethyl(methyl)amino-2-isopropylpentanenitrile hydrochloride |
2-(3,4-dimethoxyphenyl)-5-2-(3,4-dimethoxyphenyl)ethyl-methyl-amino-2-propan-2-yl-pentanenitrile hydrochloride |
2-(3,4-dimethoxyphenyl)-5-{2-(3,4-dimethoxyphenyl)ethyl(methyl)amino}-2-isopropylpentanenitrile hydrochloride |
5-(3,4-Dimethoxyphenethyl)methylamino-2-(3,4-dimethoxyphenyl)-2-isopropylvaleronitrile Hydrochloride |
alpha-3-2-(3,4-Dimethoxyphenyl)ethylmethylaminopropyl-3,4-dimethoxy-alpha-(1-methylethyl) benzeneacetonitrile hydrochloride |
Benzeneacetonitrile,4-dimethoxyphenyl)ethylmethylaminopropyl-3,4-dimethoxy-.alpha.-(1-methylethyl)-, monohydrochloride |
Verapamil hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material |
Experimental Data
Verapamil hydrochloride
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33 | umol/L | 12 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
Verapamil hydrochloride
Statistics Data
Verapamil hydrochloride
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 12 | 1 | 1 |
Statistics Data Visualization
Verapamil hydrochloride
