Compound Summary
Compound Information
Trazodone hydrochloride
Compound Name: | Trazodone hydrochloride |
Compound CID: | 62935 |
Synonyms: | Trazodone hydrochloride 25332-39-2 Trazodone Hcl Desyrel Molipaxin More... |
Iupac Name: | 2-[3-[4-(3-chlorophenyl)piperazin-1-yl]propyl]-[1,2,4]triazolo[4,3-a]pyridin-3-one;hydrochloride |
InChI: | InChI=1S/C19H22ClN5O.ClH/c20-16-5-3-6-17(15-16)23-13-11-22(12-14-23)8-4-10-25-19(26)24-9-2-1-7-18(24)21-25;/h1-3,5-7,9,15H,4,8,10-14H2;1H |
InChIKey: | OHHDIOKRWWOXMT-UHFFFAOYSA-N |
Canonical Smiles: | C1CN(CCN1CCCN2C(=O)N3C=CC=CC3=N2)C4=CC(=CC=C4)Cl.Cl |
Isomeric Smiles: | C1CN(CCN1CCCN2C(=O)N3C=CC=CC3=N2)C4=CC(=CC=C4)Cl.Cl |
Molecular Weight: | 408.3 |
Molecular Formula: | C19H23Cl2N5O |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
Trazodone hydrochloride
Molecular Weight: | 408.3 |
Molecular Formula: | C19H23Cl2N5O |
Hydrogen Bond Donor Count: | 1 |
Hydrogen Bond Acceptor Count: | 4 |
Rotatable Bond Count: | 5 |
Heavy Atom Count: | 27 |
Complexity: | 611 |
Synonyms
Trazodone hydrochloride
| Trazodone hydrochloride | Trazodone hydrochloride |
|---|---|
Trazodone hydrochloride |
25332-39-2 |
Trazodone Hcl |
Desyrel |
Molipaxin |
Bimaran |
Thombran |
Trazodone (hydrochloride) |
AF-1161 |
Trialodine |
UNII-6E8ZO8LRNM |
KB-831 |
Oleptro |
19666-36-5 |
6E8ZO8LRNM |
2-(3-(4-(3-chlorophenyl)piperazin-1-yl)propyl)-1,2,4triazolo4,3-apyridin-3(2H)-one hydrochloride |
AF-1161 (free base) |
C19H23Cl2N5O |
2-3-4-(3-chlorophenyl)piperazin-1-ylpropyl-1,2,4triazolo4,3-apyridin-3-one hydrochloride |
2-3-4-(3-chlorophenyl)piperazin-1-ylpropyl-1,2,4triazolo4,3-apyridin-3-one;hydrochloride |
MLS000069698 |
CHEBI:9655 |
1,2,4-Triazolo4,3-apyridin-3(2H)-one,2-3-4-(3-chlorophenyl)-1-piperazinylpropyl-,hydrochloride (1:1) |
Trittico |
Trazodone hydrochloride (Desyrel) |
Apo-Trazodone |
NSC-292811 |
2-(3-(4-(m-Chlorophenyl)-1-piperazinyl)propyl)-s-triazolo(4,3-a)pyridin-3(2H)-one monohydrochloride |
Devidon |
Pragmazone |
SMR000058520 |
Tombran |
Tritico |
Triticum |
Azona |
25332-39-2 (HCl) |
DSSTox_CID_24626 |
DSSTox_RID_80361 |
DSSTox_GSID_44626 |
2-3-4-(3-Chlorophenyl)-1-piperazinylpropyl-1,2,4-triazolo4,3-apyridin-3(2H)-one hydrochloride |
2-3-4-(3-chlorophenyl)piperazin-1-ylpropyl-1,2,4-triazolo4,3-apyridin-3(2H)-one hydrochloride |
Desyrel Dividose |
2-(3-(4-(3-Chlorophenyl)piperazin-1-yl)propyl)-1,2,4-triazolo(4,3-a)pyridin-3(2H)-one hydrochloride |
2-{3-4-(3-chlorophenyl)piperazin-1-ylpropyl}-2H,3H-1,2,4triazolo4,3-apyridin-3-one hydrochloride |
AF 1161 |
SR-01000000190 |
NCGC00016035-02 |
EINECS 246-855-5 |
CAS-25332-39-2 |
NSC 292811 |
Trazodone, HCl |
2-3-4-(m-Chlorophenyl)-1-piperazinylpropyl-s-triazolo4,3-apyridin-3(2H)-one monohydrochloride |
Prestwick_478 |
Desyrel (TN) |
EINECS 243-216-2 |
Trazodone hydrochloride USAN:USP:JAN |
Opera_ID_850 |
SCHEMBL61754 |
1,2,4-Triazolo(4,3-a)pyridin-3(2H)-one, 2-(3-(4-(3-chlorophenyl)-1-piperazinyl)propyl)-, monohydrochloride |
MLS000758230 |
MLS001148260 |
MLS001424009 |
SPECTRUM1503121 |
CHEMBL1200798 |
DTXSID8044626 |
HMS1568L06 |
HMS1922G09 |
Pharmakon1600-01503121 |
Trazodone hydrochloride (JAN/USP) |
BCP04922 |
HY-B0478 |
Tox21_110286 |
Tox21_302685 |
Tox21_501159 |
CCG-40299 |
CT0209 |
MFCD00079603 |
NSC292811 |
NSC758393 |
AKOS015897762 |
Tox21_110286_1 |
AC-6779 |
KS-5100 |
LP01159 |
MCULE-3098459714 |
NC00046 |
NSC-758393 |
VA11904 |
NCGC00016035-13 |
NCGC00094420-01 |
NCGC00094420-02 |
NCGC00094420-03 |
NCGC00094420-04 |
NCGC00256807-01 |
NCGC00261844-01 |
2-(3-(4-(3-Chlorophenyl)piperazin-1-y)propyl)-1,2,4-triazolo(4,3-a)pyridine-3(2H)-one hydrochloride |
s-Triazolo(4,3-a)pyridin-3(2H)-one, 2-(3-(4-(m-chlorophenyl)-1-piperazinyl)propyl)-, monohydrochloride |
EU-0101159 |
FT-0659024 |
FT-0675364 |
S2582 |
ST51015149 |
D00820 |
D97808 |
J10153 |
T 6154 |
Trazodone hydrochloride, >=99% (HPLC), powder |
332T392 |
A813950 |
A817789 |
A924854 |
2-3-4-(3-Chlorophenyl)-1-piperazinylpropyl- |
J-015941 |
SR-01000000190-2 |
SR-01000000190-8 |
WLN: T56 ANVNNJ C3- AT6N DNTJ DR CG &GH |
Q27108459 |
1,2,4-triazolo4,3-apyridin-3(2H)-one hydrochloride |
Z1550675462 |
Trazodone Hydrochloride 1.0 mg/ml in Methanol (as free base) |
Trazodone hydrochloride, United States Pharmacopeia (USP) Reference Standard |
S-Triazolo4, 2-3-4-(m-chlorophenyl)-1-piperazinylpropyl-, monohydrochloride |
S-Trizolo4, 2-3-4-(3-chlorophenyl)-1-piperazinylpropyl-, hydrochloride |
1,4-Triazolo4,3-apyridin-3(2H)-one, 2-3-4-(3-chlorophenyl)-1-piperazinylpropyl-, monohydrochloride |
2-3-4-(3-chlorophenyl)-1-piperazinylpropyl-1,2,4triazolo4,3-apyridin-3-one hydrochloride |
2-3-4-(3-chlorophenyl)piperazin-1-ylpropyl-1,2,4triazolo4,3-apyridin-3-one;hydron;chloride |
2-{3-4-(3-chlorophenyl)piperazin-1-ylpropyl}1,2,4triazolo4,3-apyridin-3(2H)-one hydrochloride |
2-{3-4-(3-chlorophenyl)piperazinylpropyl}-4-hydro-1,2,4-triazolino4,3-apyr idin-3-one, chloride |
Trazodone hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material |
Experimental Data
Trazodone hydrochloride
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33 | umol/L | -5 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
Trazodone hydrochloride
Statistics Data
Trazodone hydrochloride
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | -5 | 1 | 1 |
Statistics Data Visualization
Trazodone hydrochloride
