Compound Summary
Compound Information
methylene blue
Compound Name: | methylene blue |
Compound CID: | 6099 |
Synonyms: | methylene blue 61-73-4 Basic blue 9 Methylthioninium chloride Solvent blue 8 More... |
Iupac Name: | [7-(dimethylamino)phenothiazin-3-ylidene]-dimethylazanium;chloride |
InChI: | InChI=1S/C16H18N3S.ClH/c1-18(2)11-5-7-13-15(9-11)20-16-10-12(19(3)4)6-8-14(16)17-13;/h5-10H,1-4H3;1H/q+1;/p-1 |
InChIKey: | CXKWCBBOMKCUKX-UHFFFAOYSA-M |
Canonical Smiles: | CN(C)C1=CC2=C(C=C1)N=C3C=CC(=[N+](C)C)C=C3S2.[Cl-] |
Isomeric Smiles: | CN(C)C1=CC2=C(C=C1)N=C3C=CC(=[N+](C)C)C=C3S2.[Cl-] |
Molecular Weight: | 319.9 |
Molecular Formula: | C16H18ClN3S |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
methylene blue
Molecular Weight: | 319.9 |
Molecular Formula: | C16H18ClN3S |
Hydrogen Bond Donor Count: | 0 |
Hydrogen Bond Acceptor Count: | 4 |
Rotatable Bond Count: | 1 |
Heavy Atom Count: | 21 |
Complexity: | 483 |
Synonyms
methylene blue
| methylene blue | methylene blue |
|---|---|
methylene blue |
61-73-4 |
Basic blue 9 |
Methylthioninium chloride |
Solvent blue 8 |
Swiss Blue |
Chromosmon |
3,7-Bis(dimethylamino)phenothiazin-5-ium chloride |
Methylene Blue N |
Methylene Blue BB |
Methylene Blue anhydrous |
Bleu de methylene |
Methylene Blue chloride |
External Blue 1 |
Methylene Blue A |
Methylene Blue B |
Methylene Blue D |
Methylene Blue G |
C.I. Basic Blue 9 |
Calcozine Blue ZF |
Methylene Blue BD |
Methylene Blue BP |
Methylene Blue BX |
Methylene Blue BZ |
Methylene Blue FZ |
Methylene Blue GZ |
Methylene Blue NZ |
Methylene Blue SG |
Methylene Blue SP |
Methylene Blue ZF |
Methylene Blue ZX |
Tetramethylene Blue |
Methylene Blue 2B |
Methylenium ceruleum |
Methylene Blue BBA |
Methylene Blue BPC |
Methylene Blue HGG |
Methylene Blue IAD |
Methylene Blue JFA |
Sandocryl Blue BRL |
Methylenblau |
Methylene Blue 2BF |
Methylene Blue 2BN |
Methylene Blue 2BP |
M-B Tabs |
Rember |
Mitsui Methylene Blue |
Methylthionium chloride |
Tetramethylthionine chloride |
Leather Pure Blue HB |
Methylthionine chloride |
Modr methylenova |
Schultz No. 1038 |
Aizen Methylene Blue BH |
Aizen Methylene Blue FZ |
Methylene Blue polychrome |
Methylene Blue Zinc Free |
Yamamoto Methylene Blue B |
D And C Blue Number 1 |
Methylene Blue (Medicinal) |
Yamamoto Methylene Blue ZF |
Ext D and C Blue No. 1 |
Methylene Blue I (Medicinal) |
Cloruro de metiltioninio |
Methylene Blue NF (Medicinal) |
Methylthioninii chloridum |
Hidaco Methylene Blue Salt Free |
Methylene Blue BB (Zinc Free) |
Methylene Blue USP (Medicinal) |
Phenothiazin-5-ium, 3,7-bis(dimethylamino)-, chloride |
Chlorure de methylthioninium |
Methylene Blue USP XII (Medicinal) |
UNII-8NAP7826UB |
Methylene Blue Chloride (Biological stain) |
C.I. 52015 |
X 138 |
3,7-Bis(dimethylamino)phenazathionium chloride |
MFCD00012111 |
12262-49-6 |
8NAP7826UB |
CHEBI:6872 |
7-(dimethylamino)phenothiazin-3-ylidene-dimethylazanium;chloride |
Urolene blue |
Methylene Blue (C.I. 52015) |
CI 52015 |
105504-42-5 |
azul de metileno |
CI-52015 |
Phenothiazin-5-ium, 3,7-bis(dimethylamino)-, chloride (1:1) |
DSSTox_CID_3296 |
N-7-(dimethylamino)-3H-phenothiazin-3-ylidene-N-methylmethanaminium chloride |
Ceruleum methylenum |
DSSTox_RID_76963 |
DSSTox_GSID_23296 |
Methylenum coeruleum |
CI Basic Blue 9 |
Caswell No. 567 |
Methylenblau German |
Methylthionini chloridum |
3H-Phenothiazine, 3-methochloride |
Modr Methylenova Czech |
CHEMBL405110 |
Modr zasadita 9 |
Modr Zasadita 9 Czech |
CAS-61-73-4 |
N-(7-(dimethylamino)-3H-phenothiazin-3-ylidene)-N-methylmethanaminium chloride |
NSC3089 |
CCRIS 833 |
Metiltioninio cloruro DCIT |
Metiltioninio cloruro |
Modr Rozpoustedlova 8 Czech |
3H-Phenothiazine, 7-(dimethylamino)-3-(methylimino)-, 3-methochloride |
Modr rozpoustedlova 8 |
NSC215213 |
NSC617593 |
C.I. 52 015 |
HSDB 1405 |
NSC-215213 |
NSC-617593 |
NCGC00167496-01 |
NCGC00167496-03 |
Phenothiazin-5-ium,7-bis(dimethylamino)-, chloride |
EINECS 200-515-2 |
Methylthioninii chloridum INN-Latin |
EPA Pesticide Chemical Code 039505 |
NSC 215213 |
Cloruro de metiltioninio INN-Spanish |
WLN: T C666 BS EY INJ EUK1&1 MN1&1 &G &421 |
Provayblue |
Chlorure de methylthioninium INN-French |
7-(dimethylamino)phenothiazin-3-ylidenedimethylamine, chloride |
Lowacryl blue 9 |
Methylene Azure II |
Prestwick_326 |
Ehrlichs reagent III |
Loefflers Methylene Blue |
Methylene Blue (Inhibitor) |
SCHEMBL1351 |
MLS000719838 |
DOG (COUCH) GRASS Powder |
DTXSID0023296 |
Methylthioninium chloride INN |
C.I. Basic Blue 9 (8CI) |
HMS2598O03 |
Pharmakon1600-01505444 |
CI NO 52015 |
NSC-3089 |
Tox21_112497 |
Tox21_302087 |
NSC759135 |
s4535 |
SBB060907 |
STK018918 |
AKOS000486124 |
AKOS015916406 |
Tox21_112497_1 |
CCG-267696 |
DB09241 |
MCULE-7744087830 |
NSC-759135 |
4-(1-HYDROXY-ETHYL)-BENZOICACID |
NCGC00255351-01 |
AC-15225 |
AS-35256 |
Basic Blue 9;Tetramethylthionine chloride |
HY-14536 |
Methylene Blue, 1% w/v aqueous solution |
SMR000304367 |
ST093058 |
SY076497 |
Methylthioninium Chloride (Methylene Blue) |
Methylene Blue (C.I. 52015) BioChemica |
A0574 |
FT-0622580 |
M0501 |
ST50406802 |
C00220 |
M-3598 |
3,7-Bis(dimethylamino)-5-phenothiazinium Chloride |
Q422134 |
3,7-bis(dimethylamino)-phenothiazin-5-ium chloride salt |
7-(dimethylamino)dibenzob,e1,4-thiazin-3-yldimethylamine, chloride |
3-N,3-N,7-N,7-N-tetramethylphenothiazin-5-ium-3,7-diamine;chloride |
1341-90-8 |
152071-32-4 |
6476-03-5 |
97130-83-1 |
Experimental Data
methylene blue
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Mus musculus | 27 | mg/kg | 704 | 699 | 1 | 1013 | 980 | -0.03 | NS | UT | MALES | 24245565 | Inactive |
| Mus musculus | 27 | mg/kg | 918 | 862 | -6 | 1084 | 1121 | 0.03 | NS | TJL | FEMALES | 24245565 | Inactive |
| Mus musculus | 27 | mg/kg | 925 | 905 | -2 | 1151 | 1157 | 0.01 | NS | UM | MALES | 24245565 | Inactive |
| Mus musculus | 27 | mg/kg | 807 | 701 | -13 | 1061 | 1009 | -0.05 | NS | TJL | MALES | 24245565 | Inactive |
| Mus musculus | 27 | mg/kg | 887 | 993 | 12 | 1089 | 1159 | 0.06 | S | UM | FEMALES | 24245565 | Active |
| Mus musculus | 27 | mg/kg | 864 | 880 | 2 | 1062 | 1075 | 0.01 | NS | UT | FEMALES | 24245565 | Inactive |
Experimental Data Visualization
methylene blue
Statistics Data
methylene blue
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Mus musculus | 12 | 0.06 | 1 | 6 |
Statistics Data Visualization
methylene blue
