Compound Summary
Compound Information
138982-67-9
Compound Name: | 138982-67-9 |
Compound CID: | 60853 |
Synonyms: | 138982-67-9 Ziprasidone hydrochloride monohydrate Geodon 5-(2-(4-(Benzodisothiazol-3-yl)piperazin-1-yl)ethyl)-6-chloroindolin-2-one hydrochloride hydrate Ziprasidone HCl hydrate More... |
Iupac Name: | 5-[2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]-6-chloro-1,3-dihydroindol-2-one;hydrate;hydrochloride |
InChI: | InChI=1S/C21H21ClN4OS.ClH.H2O/c22-17-13-18-15(12-20(27)23-18)11-14(17)5-6-25-7-9-26(10-8-25)21-16-3-1-2-4-19(16)28-24-21;;/h1-4,11,13H,5-10,12H2,(H,23,27);1H;1H2 |
InChIKey: | ZCBZSCBNOOIHFP-UHFFFAOYSA-N |
Canonical Smiles: | C1CN(CCN1CCC2=C(C=C3C(=C2)CC(=O)N3)Cl)C4=NSC5=CC=CC=C54.O.Cl |
Isomeric Smiles: | C1CN(CCN1CCC2=C(C=C3C(=C2)CC(=O)N3)Cl)C4=NSC5=CC=CC=C54.O.Cl |
Molecular Weight: | 467.4 |
Molecular Formula: | C21H24Cl2N4O2S |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
138982-67-9
Molecular Weight: | 467.4 |
Molecular Formula: | C21H24Cl2N4O2S |
Hydrogen Bond Donor Count: | 3 |
Hydrogen Bond Acceptor Count: | 6 |
Rotatable Bond Count: | 4 |
Heavy Atom Count: | 30 |
Complexity: | 573 |
Synonyms
138982-67-9
| 138982-67-9 | 138982-67-9 |
|---|---|
138982-67-9 |
Ziprasidone hydrochloride monohydrate |
Geodon |
5-(2-(4-(Benzodisothiazol-3-yl)piperazin-1-yl)ethyl)-6-chloroindolin-2-one hydrochloride hydrate |
Ziprasidone HCl hydrate |
UNII-216X081ORU |
ZIPRASIDONE HYDROCHLORIDE HYDRATE |
MFCD00921885 |
Ziprasidone HCl monohydrate |
Ziprasidone (hydrochloride monohydrate) |
216X081ORU |
Zeldox |
CP-88,059-1 |
Geodon (TN) |
CHEBI:32314 |
5-2-4-(1,2-benzothiazol-3-yl)piperazin-1-ylethyl-6-chloro-1,3-dihydroindol-2-one;hydrate;hydrochloride |
NCGC00186050-01 |
5-2-4-(1,2-Benzisothiazol-3-yl)-1-piperazinylethyl-6-chloro-1,3-dihydro-2H-indol-2-one hydrochloride monohydrate |
5-2-4-(1,2-Benzisothiazol-3yl)-1-piperazinylethyl-6-chloro-1,3-dihydro-2H-indol-2-one hydrochloride |
CP 88059 |
CP-880591 |
Ziprasidone hydrochloride USAN:USP |
CP-88059-1 |
CP 88,059-1 |
zlchem 4 |
5-(2-(4-(1,2-Benzisothiazol-3-yl)-1-piperazinyl)ethyl)-6-chloro-2-indolinone monohydrochloride, monohydrate |
SCHEMBL122875 |
CHEMBL1375743 |
Ziprasidone hydrochloride (USP) |
C21H21ClN4OS.HClH2O |
DTXSID00160855 |
SYN3019 |
ZLA0004 |
BCP29919 |
Tox21_501025 |
CZ0015 |
AKOS015961662 |
CCG-222329 |
CS-1198 |
LP01025 |
ME-2112 |
Ziprasidone hydrochloride hydrate (JAN) |
NCGC00261710-01 |
2H-Indol-2-one, 5-(2-(4-(1,2-benzisothiazol-3-yl)-1-piperazinyl)ethyl)-6-chloro-1,3-dihydro-, monohydrochloride, monohydrate |
AS-16359 |
BZ164577 |
HY-17407 |
FT-0600387 |
Ziprasidone hydrochloride monohydrate- Bio-X |
CP-88059-01 |
D01939 |
T71751 |
982Z679 |
J-007206 |
Q27114865 |
Ziprasidone hydrochloride monohydrate, >=98% (HPLC), solid |
Ziprasidone for system suitability 1, European Pharmacopoeia (EP) Reference Standard |
Ziprasidone for system suitability 2, European Pharmacopoeia (EP) Reference Standard |
Ziprasidone Hydrochloride Monohydrate 1.0 mg/ml in Methanol (as anhydrous free base) |
Ziprasidone hydrochloride monohydrate, European Pharmacopoeia (EP) Reference Standard |
Ziprasidone hydrochloride, United States Pharmacopeia (USP) Reference Standard |
2H-Indol-2-one, 5-2-4-(1,2-benzisothiazol-3-yl)-1-piperazinylethyl-6-chloro-1,3-dihydro-, hydrochloride, hydrate (1:1:1) |
Ziprasidone Hydrochloride Monohydrate;CP88059; CP-88059; CP 88059; CP-88,059; CP-88,059-01 |
Experimental Data
138982-67-9
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 10 | umol/L | 16.58 | 13.15 | -20.7 | NS | N2 | 33008901 | Inactive | ||||
| Caenorhabditis elegans | 100 | umol/L | 15.16 | 13.95 | -7.966 | NS | N2 | 33008901 | Inactive |
Experimental Data Visualization
138982-67-9
Statistics Data
138982-67-9
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | -7.966 | 1 | 2 |
Statistics Data Visualization
138982-67-9
