Compound Summary
Compound Information
kanamycin
Compound Name: | kanamycin |
Compound CID: | 6032 |
Synonyms: | kanamycin KANAMYCIN A 59-01-8 Kanamycin Base Kanamycin sulfate More... |
Iupac Name: | (2R,3S,4S,5R,6R)-2-(aminomethyl)-6-[(1R,2R,3S,4R,6S)-4,6-diamino-3-[(2S,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2-hydroxycyclohexyl]oxyoxane-3,4,5-triol |
InChI: | InChI=1S/C18H36N4O11/c19-2-6-10(25)12(27)13(28)18(30-6)33-16-5(21)1-4(20)15(14(16)29)32-17-11(26)8(22)9(24)7(3-23)31-17/h4-18,23-29H,1-3,19-22H2/t4-,5+,6-,7-,8+,9-,10-,11-,12+,13-,14-,15+,16-,17-,18-/m1/s1 |
InChIKey: | SBUJHOSQTJFQJX-NOAMYHISSA-N |
Canonical Smiles: | C1C(C(C(C(C1N)OC2C(C(C(C(O2)CN)O)O)O)O)OC3C(C(C(C(O3)CO)O)N)O)N |
Isomeric Smiles: | C1[C@H]([C@@H]([C@H]([C@@H]([C@H]1N)O[C@@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CN)O)O)O)O)O[C@@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)N)O)N |
Molecular Weight: | 484.5 |
Molecular Formula: | C18H36N4O11 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
kanamycin
Molecular Weight: | 484.5 |
Molecular Formula: | C18H36N4O11 |
Hydrogen Bond Donor Count: | 11 |
Hydrogen Bond Acceptor Count: | 15 |
Rotatable Bond Count: | 6 |
Heavy Atom Count: | 33 |
Complexity: | 638 |
Synonyms
kanamycin
| kanamycin | kanamycin |
|---|---|
kanamycin |
KANAMYCIN A |
59-01-8 |
Kanamycin Base |
Kanamycin sulfate |
Kanamycine |
KanamycinA |
UNII-EQK9Q303C5 |
CHEBI:17630 |
8063-07-8 |
4,6-Diamino-2-hydroxy-1,3-cyclohexane 3,6diamino-3,6-dideoxydi-alpha-D-glucoside |
EQK9Q303C5 |
KAN |
(2R,3S,4S,5R,6R)-2-(aminomethyl)-6-(1R,2R,3S,4R,6S)-4,6-diamino-3-(2S,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yloxy-2-hydroxycyclohexyloxyoxane-3,4,5-triol |
Kanamycinum |
Kanamicina |
C18H36N4O11 |
2-(aminomethyl)-6-4,6-diamino-3-4-amino-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yloxy-2-hydroxycyclohexyloxyoxane-3,4,5-triol |
Kanamicina Italian |
KM (the Antibiotic) |
Kanamycin INN:BAN |
Kanamycine INN-French |
Kanamycinum INN-Latin |
4,6-diamino-2-hydroxy-1,3-cyclohexylene 3,6-diamino-3,6-dideoxydi-D-glucopyranoside |
(1S,2R,3R,4S,6R)-4,6-diamino-3-(6-amino-6-deoxy-alpha-D-glucopyranosyl)oxy-2-hydroxycyclohexyl 3-amino-3-deoxy-alpha-D-glucopyranoside |
HSDB 3107 |
EINECS 200-411-7 |
BRN 0061647 |
Kanamycin,(S) |
Liposomal Kanamycin |
(2R,3S,4S,5R,6R)-2-(aminomethyl)-6-(1R,2R,3S,4R,6S)-4,6-diamino-3-(2S,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yloxy-2-hydroxy-cyclohexoxytetrahydropyran-3,4,5-triol |
Amikacin EP Impurity D |
Prestwick3_000394 |
Kantrex (1:1 sulfate) |
Klebcil (1:1 sulfate) |
SCHEMBL2735 |
CHEMBL1384 |
Glucopyranoside, 4,6-diamino-2-hydroxy-1,3-cyclohexylene 3,6-diamino-3,6-dideoxydi-, D- |
BSPBio_000607 |
D-Streptamine, O-3-amino-3-deoxy-alpha-D-glucopyranosyl-(1-6)-O-(6-amino-6-deoxy-alpha-D-glucopyranosyl-(1,4))-2-deoxy- |
D-Streptamine, O-3-amino-3-deoxy-alpha-D-glucopyranosyl-(1-6)-O-(6-amino-6-deoxy-alpha-D-glucopyranosyl-(1-4))-2-deoxy- |
DivK1c_000024 |
BPBio1_000669 |
DTXSID3023184 |
KBio1_000024 |
NINDS_000024 |
ZINC8214590 |
BDBM50031282 |
AKOS025293505 |
DB01172 |
IDI1_000024 |
SMP2_000007 |
NCGC00179506-01 |
NCGC00179506-05 |
AS-14003 |
K434 |
AB00513827 |
C01822 |
K-0250 |
BRD-K08327065-065-01-9 |
Q27094615 |
Kanamycin sulfate, Antibiotic for Culture Media Use Only |
UNII-RUC37XUP2P component SBUJHOSQTJFQJX-NOAMYHISSA-N |
(1S,2R,3R,4S,6R)-4,6-diamino-3-(6-amino-6-deoxy-alpha-D-glucopyranosyloxy)-2-hydroxycyclohexyl 3-amino-3-deoxy-alpha-D-glucopyranoside |
(2R,3S,4S,5R,6R)-2-(aminomethyl)-6-((1R,2R,3S,4R,6S)-4,6-diamino-3-((2S,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)-2-hydroxycyclohexyloxy)tetrahydro-2H-pyran-3,4,5-triol |
(2R,3S,4S,5R,6R)-2-(aminomethyl)-6-{(1R,2R,3S,4R,6S)-4,6-diamino-3-{(2S,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yloxy}-2-hydroxycyclohexyloxy}oxane-3,4,5-triol |
D-Streptamine, O-3-amino-3-deoxy-alpha-D-glucopyranosyl-(1->6)-O-(6-amino-6-deoxy-alpha-D-glucopyranosyl-(1->4))-2-deoxy- |
D-Streptamine, O-3-amino-3-deoxy-alpha-D-glucopyranosyl-(1.fwdarw.6)-O-(6-amino-6-deoxy-alpha-D-glucopyranosyl-(1.fwdarw.4))-2-deoxy- |
Kanamycin solution from Streptomyces kanamyceticus, 10 mg/mL in 0.9% NaCl, sterile-filtered, BioReagent, suitable for cell culture |
Kanamycin solution from Streptomyces kanamyceticus, 50 mg/mL in 0.9% NaCl, BioReagent, liquid, sterile-filtered, suitable for cell culture |
O-3-Amino-3-deoxy-.alpha.-D-glucopyranosyl-(1->6)-O-6-amino-6-deoxy-.alpha.-D-glucopyranosyl-(1->4)-2-deoxy-D-streptamine |
O-3-amino-3-deoxy-alpha-D-glucopyranosyl-(1->6)-O-(6-amino-6-deoxy-alpha-D-glucopyranosyl-(1->4))-2-deoxy-D-streptamine |
Experimental Data
kanamycin
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Drosophila melanogaster | 200 | umol/L | 46.39 | 42.86 | -7.59 | NS | MALES | 33008901 | Inactive | ||||
| Drosophila melanogaster | 20 | umol/L | 54.37 | 52.69 | -3.09 | NS | FEMALES | 33008901 | Inactive |
Experimental Data Visualization
kanamycin
Statistics Data
kanamycin
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Drosophila melanogaster | -3.09 | 1 | 2 |
Statistics Data Visualization
kanamycin
