Compound Summary
Compound Information
PROMETHAZINE HYDROCHLORIDE
Compound Name: | PROMETHAZINE HYDROCHLORIDE |
Compound CID: | 6014 |
Synonyms: | PROMETHAZINE HYDROCHLORIDE 58-33-3 Promethazine Hcl Phenergan N,N-dimethyl-1-(10H-phenothiazin-10-yl)propan-2-amine hydrochloride More... |
Iupac Name: | N,N-dimethyl-1-phenothiazin-10-ylpropan-2-amine;hydrochloride |
InChI: | InChI=1S/C17H20N2S.ClH/c1-13(18(2)3)12-19-14-8-4-6-10-16(14)20-17-11-7-5-9-15(17)19;/h4-11,13H,12H2,1-3H3;1H |
InChIKey: | XXPDBLUZJRXNNZ-UHFFFAOYSA-N |
Canonical Smiles: | CC(CN1C2=CC=CC=C2SC3=CC=CC=C31)N(C)C.Cl |
Isomeric Smiles: | CC(CN1C2=CC=CC=C2SC3=CC=CC=C31)N(C)C.Cl |
Molecular Weight: | 320.9 |
Molecular Formula: | C17H21ClN2S |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
PROMETHAZINE HYDROCHLORIDE
Molecular Weight: | 320.9 |
Molecular Formula: | C17H21ClN2S |
Hydrogen Bond Donor Count: | 1 |
Hydrogen Bond Acceptor Count: | 3 |
Rotatable Bond Count: | 3 |
Heavy Atom Count: | 21 |
Complexity: | 298 |
Synonyms
PROMETHAZINE HYDROCHLORIDE
| PROMETHAZINE HYDROCHLORIDE | PROMETHAZINE HYDROCHLORIDE |
|---|---|
PROMETHAZINE HYDROCHLORIDE |
58-33-3 |
Promethazine Hcl |
Phenergan |
N,N-dimethyl-1-(10H-phenothiazin-10-yl)propan-2-amine hydrochloride |
Fenergan |
Promethazine (hydrochloride) |
Diprasine |
Diprazin |
Fellozine |
Pipolfen |
Pipolphen |
Romergan |
Ganphen |
Plletia |
Remsed |
Atosil |
Promethazine chloride |
Promethiazin |
V GAN |
Lergigan |
Pyrethia |
Promethazine monohydrochloride |
Zipan-25 |
HL 8700 |
N-(2-Dimethylaminopropyl-1)phenothiazine hydrochloride |
10-2-(Dimethylamino)propylphenothiazine hydrochloride |
ZIPAN-50 |
MFCD00012652 |
N,N-dimethyl-1-phenothiazin-10-ylpropan-2-amine;hydrochloride |
N-(2-Dimethylamino-2-methyl)ethylphenothiazine hydrochloride |
10-(3-Dimethylaminoisopropyl)phenothiazine hydrochloride |
3277 R.P. |
MLS000069398 |
10-(2-Dimethylamino-1-propyl)phenothiazine hydrochloride |
CHEBI:8462 |
Farganesse |
58-33-3 (HCl) |
Allerfen |
Duplamin |
Frinova |
Goodnight |
Hibechin |
Histantil |
Kinetosin |
Phenadoz |
Phencen |
Primine |
Promantine |
Promine |
Proneurin |
SMR000058379 |
Soporil |
Bonnox |
Closin |
Dorme |
Prome |
(+-)-10-(2-(Dimethylamino)propyl)phenothiazine monohydrochloride |
Prometh Fortis |
Prometh Plain |
Eusedon Mono |
Phenergan Fortis |
DSSTox_CID_1192 |
Promethazine.HCl |
PMS Promethazine |
Mymethazine Fortis |
Promethazine Plain |
DSSTox_RID_76002 |
DSSTox_GSID_21192 |
Anergan 25 |
Anergan 50 |
PHENERGAN PLAIN |
Promethiazin German |
CCRIS 5873 |
Phenergan hydrochloride |
EINECS 200-375-2 |
NSC 231688 |
SR-01000002993 |
Phenergan (TN) |
Promethegan (TN) |
10-(2-Dimethylaminopropyl)phenothiazine hydrochloride |
component of Mepergan |
Promethazine hydrochloride USP:JAN |
Promethazine-D3 HCl |
1435933-86-0 |
10-(2-(Dimethylamino)propyl)phenothiazine monohydrochloride |
CPD000058379 |
Phenothiazine, 10-(2-(dimethylamino)-propyl)-, hydrochloride |
Promethazine hydrochlorine |
CAS-58-33-3 |
Opera_ID_1745 |
10H-Phenothiazine-10-ethanamine, N,N,alpha-trimethyl-, monohydrochloride |
SCHEMBL41904 |
MLS001074184 |
MLS002548850 |
SPECTRUM1500510 |
CHEMBL1200750 |
DTXSID3021192 |
Promethazine hydrochloride solution |
HMS1570B18 |
HMS1920L16 |
Pharmakon1600-01500510 |
HY-B0781 |
N,N-dimethyl-1-phenothiazin-10-yl-propan-2-amine hydrochloride |
Phenothiazine, 10-(2-(dimethylamino)propyl)-, monohydrochloride |
Tox21_202264 |
Tox21_302878 |
Tox21_500899 |
NSC231688 |
NSC757301 |
s4293 |
AKOS016339657 |
CCG-207895 |
CS-3543 |
KS-1385 |
LP00899 |
MCULE-6615710182 |
NC00471 |
NSC-231688 |
NSC-757301 |
Promethazine hydrochloride (JP17/USP) |
10H-Phenothiazine-10-ethanamine, N,N,alpha-trimethyl-, monohydrochloride, (+-)- |
NCGC00089735-04 |
NCGC00094215-01 |
NCGC00094215-02 |
NCGC00094215-03 |
NCGC00094215-04 |
NCGC00094215-05 |
NCGC00256588-01 |
NCGC00259813-01 |
NCGC00261584-01 |
AC-12482 |
BP166198 |
H509 |
AB0013086 |
DB-053186 |
EU-0100899 |
P2029 |
ST51015100 |
SW197234-3 |
D00480 |
D92182 |
J10089 |
P 4651 |
WLN: T C666 BN ISJ B1Y1&N1&1 &GH |
A831833 |
SR-01000002993-2 |
SR-01000002993-7 |
W-105399 |
Q27108086 |
F0138-3355 |
Promethazine hydrochloride 100 microg/mL in Acetonitrile |
Z1259273234 |
((c)I)-Promethazine-d4 HCl (phenothiazine-1,3,7,9-d4) |
N,N-dimethyl-1-(10-phenothiazinyl)-2-propanamine hydrochloride |
N-(2-Dimethylamino-2-methylaethyl)-phenothiazin hydrochlorid" |
N-(2-Dimethylamino-2-methylethyl)phenothiazine hydrochloride |
Promethazine hydrochloride, VETRANAL(TM), analytical standard |
N,N-dimethyl-1-phenothiazin-10-ylpropan-2-amine;hydron;chloride |
10H-Phenothiazine-10-ethanamine,N,.alpha.-trimethyl-, monohydrochloride |
DIMETHYL1-(10H-PHENOTHIAZIN-10-YL)PROPAN-2-YLAMINE HYDROCHLORIDE |
N,N-Dimethyl-1-(10H-phenothiazin-10-yl)-2-propanamine hydrochloride |
Promethazine Hydrochloride 1.0 mg/ml in Dimethyl Sulfoxide (as free base) |
Promethazine hydrochloride, European Pharmacopoeia (EP) Reference Standard |
Promethazine hydrochloride, vial of 25 mg, certified reference material |
10H-Phenothiazine-10-ethanamine, N,N,.alpha.-trimethyl-, hydrochloride (1:1) |
10H-Phenothiazine-10-ethanamine, N,N,alpha-trimethyl-, hydrochloride (1:1) |
Promethazine for peak identification, European Pharmacopoeia (EP) Reference Standard |
Promethazine Hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material |
Promethazine hydrochloride, United States Pharmacopeia (USP) Reference Standard |
Experimental Data
PROMETHAZINE HYDROCHLORIDE
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Drosophila melanogaster | 20 | umol/L | 52.83 | 58.6 | 10.91 | S | FEMALES | 33008901 | Active | ||||
| Drosophila melanogaster | 200 | umol/L | 47.16 | 47.64 | 1.02 | NS | MALES | 33008901 | Inactive | ||||
| Caenorhabditis elegans | 176 | umol/L | 32 | S | N2 | 24134630 | Active | ||||||
| Caenorhabditis elegans | 33 | umol/L | 32 | S | N2 | 33683565 | Active |
Experimental Data Visualization
PROMETHAZINE HYDROCHLORIDE
Statistics Data
PROMETHAZINE HYDROCHLORIDE
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 32 | 2 | 2 | |
| Drosophila melanogaster | 10.91 | 1 | 2 |
Statistics Data Visualization
PROMETHAZINE HYDROCHLORIDE
