Compound Summary
Compound Information
RALOXIFENE HYDROCHLORIDE
Compound Name: | RALOXIFENE HYDROCHLORIDE |
Compound CID: | 54900 |
Synonyms: | RALOXIFENE HYDROCHLORIDE 82640-04-8 Raloxifene Hcl Keoxifene hydrochloride Evista More... |
Iupac Name: | [6-hydroxy-2-(4-hydroxyphenyl)-1-benzothiophen-3-yl]-[4-(2-piperidin-1-ylethoxy)phenyl]methanone;hydrochloride |
InChI: | InChI=1S/C28H27NO4S.ClH/c30-21-8-4-20(5-9-21)28-26(24-13-10-22(31)18-25(24)34-28)27(32)19-6-11-23(12-7-19)33-17-16-29-14-2-1-3-15-29;/h4-13,18,30-31H,1-3,14-17H2;1H |
InChIKey: | BKXVVCILCIUCLG-UHFFFAOYSA-N |
Canonical Smiles: | C1CCN(CC1)CCOC2=CC=C(C=C2)C(=O)C3=C(SC4=C3C=CC(=C4)O)C5=CC=C(C=C5)O.Cl |
Isomeric Smiles: | C1CCN(CC1)CCOC2=CC=C(C=C2)C(=O)C3=C(SC4=C3C=CC(=C4)O)C5=CC=C(C=C5)O.Cl |
Molecular Weight: | 510 |
Molecular Formula: | C28H28ClNO4S |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
RALOXIFENE HYDROCHLORIDE
Molecular Weight: | 510 |
Molecular Formula: | C28H28ClNO4S |
Hydrogen Bond Donor Count: | 3 |
Hydrogen Bond Acceptor Count: | 6 |
Rotatable Bond Count: | 7 |
Heavy Atom Count: | 35 |
Complexity: | 655 |
Synonyms
RALOXIFENE HYDROCHLORIDE
| RALOXIFENE HYDROCHLORIDE | RALOXIFENE HYDROCHLORIDE |
|---|---|
RALOXIFENE HYDROCHLORIDE |
82640-04-8 |
Raloxifene Hcl |
Keoxifene hydrochloride |
Evista |
Keoxifene |
(6-Hydroxy-2-(4-hydroxyphenyl)benzobthiophen-3-yl)(4-(2-(piperidin-1-yl)ethoxy)phenyl)methanone hydrochloride |
Raloxifene (hydrochloride) |
LY 156758 |
UNII-4F86W47BR6 |
C28H28ClNO4S |
LY156758 |
LY-156758 |
2-(4-hydroxyphenyl)-3-({4-2-(piperidin-1-yl)ethoxyphenyl}carbonyl)-1-benzothiophen-6-ol hydrochloride |
CHEBI:50740 |
Evista (Raloxifene Hydrochloride) |
4F86W47BR6 |
Optruma |
MFCD01938233 |
6-Hydroxy-2-(p-hydroxyphenyl)benzo(b)thien-3-yl-p-(2-piperidinoethoxy)phenyl ketone, hydrochloride |
DSSTox_CID_14181 |
DSSTox_RID_79119 |
DSSTox_GSID_34181 |
6-Hydroxy-2-(4-hydroxyphenyl)benzobthien-3-yl4-2-(1-piperidinyl)ethoxyphenylmethanone hydrochloride |
6-hydroxy-2-(4-hydroxyphenyl)-1-benzothiophen-3-yl-4-(2-piperidin-1-ylethoxy)phenylmethanone;hydrochloride |
SMR000058508 |
NCGC00015889-05 |
CAS-82640-04-8 |
C28H27NO4S.HCl |
Loxifen |
SR-01000076102 |
CDT-Raloxifene |
Raloxifene-d4 HCl |
Evista (TN) |
Prestwick_1035 |
Raloxifene hydrochloride USAN:USP |
Methanone, hydrochloride |
LY139481 hydrochloride |
LY156758 hydrochloride |
CHEMBL1116 |
SCHEMBL19077 |
cc-148 |
MLS000859902 |
MLS001332533 |
MLS001332534 |
MLS002222293 |
Raloxifene hydrochloride, solid |
Evista, Raloxifene hydrochloride |
Raloxifene hydrochloride- Bio-X |
DTXSID1034181 |
LY156758 (Keoxifene) HCl |
LY-139481 HCl |
HMS1570N05 |
Pharmakon1600-01505622 |
AMY23426 |
BCP05713 |
Raloxifene hydrochloride (JAN/USP) |
Tox21_110255 |
Tox21_302369 |
Tox21_501051 |
HY-13738A |
NSC706725 |
NSC759285 |
s1227 |
AKOS008131940 |
Tox21_110255_1 |
AC-8390 |
CCG-213497 |
CS-1775 |
DS-2162 |
KS-1102 |
LP01051 |
MCULE-7336063262 |
NC00665 |
NSC 706725 |
NSC 759285 |
NSC-706725 |
NSC-759285 |
VA11647 |
NCGC00015889-03 |
NCGC00015889-11 |
NCGC00092353-01 |
NCGC00092353-03 |
NCGC00094334-01 |
NCGC00094334-02 |
NCGC00255153-01 |
NCGC00261736-01 |
BR164310 |
Methanone, (6-hydroxy-2-(4-hydroxyphenyl)benzo(b)thien-3-yl)(4-(2-(1-piperidinyl)ethoxy)phenyl)-, hydrochloride |
Methanone, 6-hydroxy-2-(4-hydroxyphenyl)benzobthien-3-yl4-2-(1-piperidinyl)ethoxyphenyl-,hydrochloride (1:1) |
AB0020647 |
EU-0101051 |
FT-0630912 |
R0109 |
SW197106-5 |
V1611 |
EN300-52517 |
D02217 |
J90021 |
R 1402 |
68523-EP2270008A1 |
68523-EP2292617A1 |
68523-EP2298768A1 |
68523-EP2308855A1 |
640R048 |
A840401 |
Q-201656 |
SR-01000076102-2 |
SR-01000076102-9 |
Q27122215 |
(6-OXO-1,6-DIHYDRO-PYRIDAZIN-3-YLOXY)-ACETICACID |
Raloxifene hydrochloride, European Pharmacopoeia (EP) Reference Standard |
Raloxifene Hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material |
Raloxifene hydrochloride, United States Pharmacopeia (USP) Reference Standard |
(6-Hydroxy-2-(4-hydroxyphenyl)benzobthiophen-3-yl)-(4-(2-(piperidin-1-yl)ethoxy)phenyl)methanone hydrochloride |
(6-OH-2-(4-OH-Ph)benzobthiophen-3-yl)(4-(2-(piperidin-1-yl)ethoxy)Ph)methanone hydrochloride |
6-hydroxy-2-(4-hydroxyphenyl)-1-benzothien-3-yl4-(2-piperidin-1-ylethoxy)phenylmethanone hydrochloride |
6-hydroxy-2-(4-hydroxyphenyl)-benzobthien-3-yl4-2-(1-piperidinyl)ethoxyphenyl-methanone hydrochloride |
6-Hydroxy-2-(4-hydroxyphenyl)benzo bthien-3-yl4-2-(1-piperidinyl)ethoxyphenyl-methanone hydrochloride |
6-Hydroxy-2-(4-hydroxyphenyl)benzobthien-3-yl4-2-(1-piperidinyl)ethoxyphenyl-methanone hydrochloride |
6-hydroxy-2-(4-hydroxyphenyl)benzobthien-3-yl4-2-(1-piperidinyl)ethoxyphenyl-methanone, monohydrochloride |
6-Hydroxy-2-(4-hydroxyphenyl)benzobthiophen-3-yl4-2-(1-piperidinyl)ethoxyphenylmethanone Hydrochloride |
6-hydroxy-24-hydroxyphenyl)benzo bthien-3-yl4-2-(1-piperidinyl)ethoxyphenylmethanone hydrochloride |
6-hydroxy-24-hydroxyphenyl)benzo bthien3-yl4-2-(1-piperidinyl)ethoxyphenylmethanone hydrochloride |
6-hydroxy-24-hydroxyphenyl)benzobthien-3-yl4-2-(1-piperidinyl)ethoxyphenylmethanone hydrochloride |
1-2-(4-{6-hydroxy-2-(4-hydroxyphenyl)-1-benzothiophen-3-ylcarbonyl}phenoxy)ethylpiperidinium chloride |
6-hydroxy-2-(4-hydroxyphenyl)-3- 4-(2-piperidinoethoxy)benzoylbenzobthiophene, hydrochloride |
6-hydroxy-2-(4-hydroxyphenyl)-3-4-(2-piperidinoethoxy)benzoyl-benzob-thiophene hydrochloride |
6-hydroxy-2-(4-hydroxyphenyl)-3-4-(2-piperidinoethoxy)benzoyl-benzobthiophene hydrochloride |
6-hydroxy-2-(4-hydroxyphenyl)benzobthien-3-yl 4-2-(1-piperidinyl)ethoxyphenyl methanone hydrochloride |
6-hydroxy-2-(4-hydroxyphenyl)benzobthiophen-3-yl 4-2-(1-piperidinyl)ethoxyphenyl ketone hydrochloride |
Raloxifene hydrochloride for peak identification, European Pharmacopoeia (EP) Reference Standard |
Experimental Data
RALOXIFENE HYDROCHLORIDE
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33 | umol/L | 13 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
RALOXIFENE HYDROCHLORIDE
Statistics Data
RALOXIFENE HYDROCHLORIDE
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 13 | 1 | 1 |
Statistics Data Visualization
RALOXIFENE HYDROCHLORIDE
