Compound Summary
Compound Information
pravastatin
Compound Name: | pravastatin |
Compound CID: | 54687 |
Synonyms: | pravastatin 81093-37-0 Pravastatina Pravastatine Pravastatinum More... |
Iupac Name: | (3R,5R)-7-[(1S,2S,6S,8S,8aR)-6-hydroxy-2-methyl-8-[(2S)-2-methylbutanoyl]oxy-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]-3,5-dihydroxyheptanoic acid |
InChI: | InChI=1S/C23H36O7/c1-4-13(2)23(29)30-20-11-17(25)9-15-6-5-14(3)19(22(15)20)8-7-16(24)10-18(26)12-21(27)28/h5-6,9,13-14,16-20,22,24-26H,4,7-8,10-12H2,1-3H3,(H,27,28)/t13-,14-,16+,17+,18+,19-,20-,22-/m0/s1 |
InChIKey: | TUZYXOIXSAXUGO-PZAWKZKUSA-N |
Canonical Smiles: | CCC(C)C(=O)OC1CC(C=C2C1C(C(C=C2)C)CCC(CC(CC(=O)O)O)O)O |
Isomeric Smiles: | CC[C@H](C)C(=O)O[C@H]1C[C@@H](C=C2[C@H]1[C@H]([C@H](C=C2)C)CC[C@H](C[C@H](CC(=O)O)O)O)O |
Molecular Weight: | 424.5 |
Molecular Formula: | C23H36O7 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
pravastatin
Molecular Weight: | 424.5 |
Molecular Formula: | C23H36O7 |
Hydrogen Bond Donor Count: | 4 |
Hydrogen Bond Acceptor Count: | 7 |
Rotatable Bond Count: | 11 |
Heavy Atom Count: | 30 |
Complexity: | 656 |
Synonyms
pravastatin
| pravastatin | pravastatin |
|---|---|
pravastatin |
81093-37-0 |
Pravastatina |
Pravastatine |
Pravastatinum |
Pravachol |
Pravastatin acid |
PRAVASTATIN SODIUM |
UNII-KXO2KT9N0G |
(3R,5R)-7-(1S,2S,6S,8S,8aR)-6-hydroxy-2-methyl-8-(2S)-2-methylbutanoyloxy-1,2,6,7,8,8a-hexahydronaphthalen-1-yl-3,5-dihydroxyheptanoic acid |
KXO2KT9N0G |
CHEMBL1144 |
(3R,5R)-3,5-dihydroxy-7-(1S,2S,6S,8S,8aR)-6-hydroxy-2-methyl-8-{(2S)-2-methylbutanoyloxy}-1,2,6,7,8,8a-hexahydronaphthalen-1-ylheptanoic acid |
Eptastatin |
CHEBI:63618 |
Pravastatine French |
Pravastatinum Latin |
Pravastatina Spanish |
Pravastatin INN:BAN |
(3R,5R)-7-(1S,2S,6S,8S,8aR)-6-hydroxy-2-methyl-8-{(2S)-2-methylbutanoyloxy}-1,2,6,7,8,8a-hexahydronaphthalen-1-yl-3,5-dihydroxyheptanoic acid |
(betaR,deltaR,1S,2S,6S,8S,8aR)-1,2,6,7,8,8a-Hexahydro-beta,delta,6-trihydroxy-2-methyl-8-(2S)-2-methyl-1-oxobutoxy-1-naphthaleneheptanoic acid |
Mevalothin |
Pravator (TN) |
(+)-(3R,5R)-3,5-dihydroxy-7-(1S,2S,6S,8S,8aR)-6-hydroxy-2-methyl-8-{(S)-2-methylbutyryloxy}-1,2,6,7,8,8a-hexahydro-1-naphthylheptanoic acid |
Pravastatin (INN) |
CCRIS 7557 |
C10AA03 |
3beta-Hydroxycompactin |
KS-5015 |
SCHEMBL1117 |
BIDD:GT0773 |
GTPL2953 |
DTXSID6023498 |
BDBM20688 |
HSDB 8368 |
HMS3715P11 |
ACT02637 |
HY-B0165 |
ZINC3798763 |
1,4-Butanedisulfonicaciddisodiumsalt |
LMFA05000695 |
s5713 |
AKOS015895229 |
CCG-221195 |
DB00175 |
NCGC00188962-01 |
NCGC00188962-02 |
1,2,6,7,8,8a-hexahydro-beta,delta,6-trihydroxy-2-methyl-8-(2-methyl-1-oxobutoxy)-, (1S-(1alpha(betaS*,deltaS*),2alpha,6alpha,8beta(R*),8aalpha))-1-Naphthaleneheptanoic acid |
1-Naphthaleneheptanoic acid, 1,2,6,7,8,8a-hexahydro-beta,delta,6-trihydroxy-2-methyl-8-((2S)-2-methyl-1-oxobutoxy)-, (betaR,deltaR,1S,2S,6S,8S,8aR)- |
1-Naphthaleneheptanoic acid, 1,2,6,7,8,8a-hexahydro-beta,delta,6-trihydroxy-2-methyl-8-(2-methyl-1-oxobutoxy)-, (1S-(1alpha(betas*,deltas*),2alpha,6alpha,8beta(R*),8aalpha))- |
C01844 |
D08410 |
H12037 |
093P370 |
A840039 |
SR-01000781259 |
Q1240093 |
SR-01000781259-2 |
BRD-K60511616-236-01-4 |
BRD-K60511616-236-02-2 |
BRD-K60511616-236-08-9 |
(3R,5R)-3,5-dihydroxy-7-((1S,2S,6S,8S,8aR)-6-hydroxy-2-methyl-8-((S)-2-methylbutanoyloxy)-1,2,6,7,8,8a-hexahydronaphthalen-1-yl)heptanoic acid |
(3R,5R)-3,5-dihydroxy-7-(1S,2S,6S,8S)-6-hydroxy-2-methyl-8-(2S)-2-methylbutanoyloxy-1,2,6,7,8,8a-hexahydronaphthalen-1-ylheptanoic acid |
Experimental Data
pravastatin
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Brachionus manjavacas | 0.5 | umol/L | 32 | S | B. manjavacas | 29340835 | Active |
Experimental Data Visualization
pravastatin
Statistics Data
pravastatin
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Brachionus manjavacas | 32 | 1 | 1 |
Statistics Data Visualization
pravastatin
