Compound Summary

  Compound Information
 piroxicam

Compound Name:

piroxicam

Compound CID:

54676228

Synonyms:

piroxicam

36322-90-4

Feldene

Piroxicamum

Pyroxycam

More...

Iupac Name:

4-hydroxy-2-methyl-1,1-dioxo-N-pyridin-2-yl-1lambda6,2-benzothiazine-3-carboxamide

InChI:

InChI=1S/C15H13N3O4S/c1-18-13(15(20)17-12-8-4-5-9-16-12)14(19)10-6-2-3-7-11(10)23(18,21)22/h2-9,19H,1H3,(H,16,17,20)

InChIKey:

QYSPLQLAKJAUJT-UHFFFAOYSA-N

Canonical Smiles:

CN1C(=C(C2=CC=CC=C2S1(=O)=O)O)C(=O)NC3=CC=CC=N3

Isomeric Smiles:

CN1C(=C(C2=CC=CC=C2S1(=O)=O)O)C(=O)NC3=CC=CC=N3

Molecular Weight:

331.3

Molecular Formula:

C15H13N3O4S

  Compound Structure
 2D Structure:
 3D Structure:
  Computed Properties
 piroxicam

Molecular Weight:

331.3

Molecular Formula:

C15H13N3O4S

Hydrogen Bond Donor Count:

2

Hydrogen Bond Acceptor Count:

6

Rotatable Bond Count:

2

Heavy Atom Count:

23

Complexity:

611

  Synonyms
 piroxicam

piroxicam piroxicam

piroxicam

36322-90-4

Feldene

Piroxicamum

Pyroxycam

Roxicam

Piroftal

BAXO

CP-16171

4-Hydroxy-2-methyl-N-(pyridin-2-yl)-2H-benzoe1,2thiazine-3-carboxamide 1,1-dioxide

CP 16171

CHF 1251

2H-1,2-Benzothiazine-3-carboxamide, 4-hydroxy-2-methyl-N-2-pyridinyl-, 1,1-dioxide

UNII-13T4O6VMAM

NSC 666076

Piroxicam (Feldene)

4-Hydroxy-2-methyl-N-(2-pyridyl)-2H-1,2-benzothiazine-3-carboxamide-1,1-dioxide

13T4O6VMAM

4-Hydroxy-2-methyl-3-(pyrid-2-yl-carbamoyl)-2H-1,2-benzothiazine 1,1-dioxide

4-Hydroxy-2-methyl-N-(2-pyridyl)-2H-1,2-benzothiazin-3-caboxyamid-1,1-dioxid

4-Hydroxy-2-methyl-N-2-pyridyl-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide

MLS000069644

CHEBI:8249

MFCD00057317

NSC666076

4-hydroxy-2-methyl-N-pyridin-2-yl-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide

NSC-666076

NCGC00015823-02

Artroxicam

Bruxicam

Caliment

Flogobene

Geldene

Improntal

Larapam

Piroflex

Reudene

Roxiden

Sasulen

SMR000035997

Solocalm

Erazon

Pirkam

piroxicam usp

Riacen

Zunden

Roxam

CP-16,171

CAS-36322-90-4

DSSTox_CID_1170

4-hydroxy-2-methyl-1,1-dioxo-N-pyridin-2-yl-1lambda6,2-benzothiazine-3-carboxamide

DSSTox_RID_75990

DSSTox_GSID_21170

Piroxicamum INN-Latin

Rosiden

Felden

Feldene Fast

Feldene Gel

(4-hydroxy-2-methyl-1,1-dioxobenzoe1,2-thiazin-3-yl)-N-(2-pyridyl)carboxamid e

4-Hydroxy-2-methyl-N-(2-pyridyl)-2H-1,2-benzothiazine-3-carboxamide 1,1-Dioxide

4-hydroxy-2-methyl-N-(pyridin-2-yl)-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide

4-hydroxy-2-methyl-N-2-pyridinyl-2H-1,2-benzothiazine-3-carboxamide-1,1-dioxide

(Z)-3-(hydroxy(pyridin-2-ylamino)methylene)-2-methyl-2H-benzoe1,2thiazin-4(3H)-one 1,1-dioxide

Feldene (TN)

CCRIS 3719

SR-01000000199

EINECS 252-974-3

AK1015

BRN 0627692

4-hydroxy-2-methyl-1,1-dioxo-N-pyridin-2-yl-1?^{6},2-benzothiazine-3-carboxamide

Piroxicam,(S)

Prestwick_573

4-Hydroxy-2-methyl-N-(2-pyridyl)-2H-1,2-benzothiazin-3-caboxyamid-1,1-dioxid German

Piroxicam USAN:USP:INN:BAN:JAN

piroxicam:malonic acid

Spectrum_001115

Tocris-0960

Piroxicam-(methyl-d3)

Opera_ID_442

Piroxicam: Form Alpha1

Piroxicam: Form Alpha2

Prestwick0_000211

Prestwick1_000211

Prestwick2_000211

Prestwick3_000211

Spectrum2_001287

Spectrum3_000780

Spectrum4_000968

Spectrum5_001445

Lopac-P-5654

CHEMBL527

P 5654

BIDD:PXR0154

Lopac0_000900

Oprea1_714707

SCHEMBL13462

SCHEMBL21350

BSPBio_000221

BSPBio_001030

BSPBio_002460

KBioGR_000370

KBioGR_001315

KBioSS_000370

KBioSS_001595

MLS000038002

MLS001148207

MLS001304054

MLS004774122

DivK1c_000369

SPECTRUM1500491

SPBio_001293

SPBio_002142

Piroxicam (JP17/USP/INN)

BPBio1_000245

GTPL7273

Piroxicam, >=98% (TLC)

SCHEMBL3703617

Piroxicam for system suitability

CHEMBL1518938

DTXSID5021170

BCBcMAP01_000176

BDBM85245

HMS501C11

KBio1_000369

KBio2_000370

KBio2_001595

KBio2_002938

KBio2_004163

KBio2_005506

KBio2_006731

KBio3_000719

KBio3_000720

KBio3_001680

NINDS_000369

Piroxicam 1.0 mg/ml in Methanol

Bio1_000363

Bio1_000852

Bio1_001341

Bio2_000355

Bio2_000835

HMS1362D11

HMS1568L03

HMS1792D11

HMS1920H22

HMS1990D11

HMS2089B06

HMS2092A05

HMS2095L03

HMS2231G03

HMS3262D22

HMS3267I03

HMS3369B07

HMS3403D11

HMS3414H17

HMS3429L03

HMS3655C04

HMS3678H15

HMS3712L03

HMS3884C08

Pharmakon1600-01500491

BCP02919

HY-B0253

NSC_4856

Tox21_110231

Tox21_200151

Tox21_500900

BBL016493

CCG-36403

NSC757284

s1713

STK177288

ZINC12466469

ZINC51133897

ZINC87724780

AKOS000714958

AKOS025312555

AKOS026749939

Tox21_110231_1

AM84917

DB00554

KS-5322

LP00900

MCULE-1939282084

NSC-757284

SDCCGSBI-0050875.P005

(4-Hydroxy-2-methyl-1,1-dioxobenzoe1,2-thiazin-3-yl)-N-(2-pyridyl)carboxamide

2H-1,2-Benzothiazine-3-carboxamide,4-hydroxy-2-methyl-N-2-pyridinyl-, 1,1-dioxide

3,4-Dihydro-2-methyl-4-oxo-N-2-pyridyl-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide

4-Hydroxy-2-methyl-N-2-pyridinyl-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide

IDI1_000369

IDI1_002110

NCGC00015823-01

NCGC00015823-03

NCGC00015823-04

NCGC00015823-05

NCGC00015823-06

NCGC00015823-07

NCGC00015823-08

NCGC00015823-09

NCGC00015823-10

NCGC00015823-11

NCGC00015823-12

NCGC00015823-13

NCGC00015823-14

NCGC00015823-15

NCGC00015823-17

NCGC00015823-18

NCGC00015823-20

NCGC00015823-29

NCGC00021244-03

NCGC00021244-05

NCGC00021244-06

NCGC00021244-07

NCGC00021244-08

NCGC00021244-09

NCGC00188982-01

NCGC00257705-01

NCGC00261585-01

AC-24190

NCI60_022912

ST069379

BCP0726000299

SBI-0050875.P004

AB0011706

CAS_36322-90-4

Piroxicam, meets USP testing specifications

EU-0100900

FT-0630590

FT-0673949

P1905

SW219862-1

EN300-70724

A19556

C01608

D00127

D70554

J10253

AB00052074-21

AB00052074-22

AB00052074_23

AB00052074_24

322P904

Q408676

SR-01000000199-3

SR-01000000199-5

SR-01000000199-9

W-106626

SR-01000000199-12

F0001-2399

Piroxicam, British Pharmacopoeia (BP) Reference Standard

Z1259192069

Piroxicam, European Pharmacopoeia (EP) Reference Standard

Piroxicam, United States Pharmacopeia (USP) Reference Standard

Piroxicam, Pharmaceutical Secondary Standard; Certified Reference Material

4-hydroxy-2-methyl-1,1-dioxo-N-(2-pyridyl)-1$l^{6},2-benzothiazine-3-carboxamide

4-hydroxy-2-methyl-1,1-dioxo-N-(pyridin-2-yl)-2H-1$l^{6},2-benzothiazine-3-carboxamide

4-Hydroxy-2-methyl-3-(2-pyridylcarbamoyl)-2H-1,2-benzothiazine 1,1-Dioxide

4-Hydroxy-2-methyl-N-(2-pyridyl)-2H-1,2-benzo-thiazine-3-carboxamide1,1-dioxide

4-Hydroxy-2-methyl-N-2-pyridinyl-2H-1,2-benzothiazine-3-carboxamide1,1-dioxide

N-(2-pyridyl)-4-hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide

1044566-76-8

1488516-58-0

3-{hydroxy(pyridin-2-yl)aminomethylidene}-2-methyl-3,4-dihydro-2H-1$l^{6},2-benzothiazine-1,1,4-trione

3-{hydroxy(pyridin-2-yl)aminomethylidene}-2-methyl-3,4-dihydro-2H-1lambda6,2-benzothiazine-1,1,4-trione

4-hydroxy-2-methyl-1,1-dioxo-N-(2-pyridyl)-1,2-dihydro-1lambda,2-benzothiazine-3-carboxamide

4-Hydroxy-2-methyl-N-(2-pyridyl)-2H-1,2-benzothiazine -3-carboxamide-1,1-dioxide malonic acid
  Experimental Data
 piroxicam

Species Dosage Unit CG Lifespan(AVG/MED days) TG Lifespan(AVG/MED days) Lifespan Change(AVG/MED%) CG Lifespan(MAX days) TG Lifespan(MAX days) Lifespan Change(MAX%) Significant Strain Gender PubMed Active Label
Caenorhabditis elegans 100 umol/L 15.99 16.35 2.194 NS N2 33008901 Inactive
Drosophila melanogaster 200 umol/L 42.22 43.94 4.08 NS MALES 33008901 Inactive
Drosophila melanogaster 20 umol/L 47.99 52.68 9.77 NS FEMALES 33008901 Inactive
Caenorhabditis elegans 10 umol/L 16.18 15.73 -2.757 NS N2 33008901 Inactive
Caenorhabditis elegans 33 umol/L -2 NS N2 24134630 Inactive
  Experimental Data Visualization
 piroxicam

  Statistics Data
 piroxicam

Species Lifespan Change(AVG/MED%) Lifespan Change(MAX%) Count Reference Count Data point
Caenorhabditis elegans 2.194 2 3
Drosophila melanogaster 9.77 1 2
  Statistics Data Visualization
 piroxicam

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