Compound Summary
Compound Information
tetracycline
Compound Name: | tetracycline |
Compound CID: | 54675776 |
Synonyms: | tetracycline 60-54-8 Deschlorobiomycin Tetracyclinum Achromycin More... |
Iupac Name: | (4S,4aS,5aS,6S,12aR)-4-(dimethylamino)-1,6,10,11,12a-pentahydroxy-6-methyl-3,12-dioxo-4,4a,5,5a-tetrahydrotetracene-2-carboxamide |
InChI: | InChI=1S/C22H24N2O8/c1-21(31)8-5-4-6-11(25)12(8)16(26)13-9(21)7-10-15(24(2)3)17(27)14(20(23)30)19(29)22(10,32)18(13)28/h4-6,9-10,15,25-26,29,31-32H,7H2,1-3H3,(H2,23,30)/t9-,10-,15-,21+,22-/m0/s1 |
InChIKey: | NWXMGUDVXFXRIG-WESIUVDSSA-N |
Canonical Smiles: | CC1(C2CC3C(C(=O)C(=C(C3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)N(C)C)O |
Isomeric Smiles: | C[C@@]1([C@H]2C[C@H]3[C@@H](C(=O)C(=C([C@]3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)N(C)C)O |
Molecular Weight: | 444.4 |
Molecular Formula: | C22H24N2O8 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
tetracycline
Molecular Weight: | 444.4 |
Molecular Formula: | C22H24N2O8 |
Hydrogen Bond Donor Count: | 6 |
Hydrogen Bond Acceptor Count: | 9 |
Rotatable Bond Count: | 2 |
Heavy Atom Count: | 32 |
Complexity: | 971 |
Synonyms
tetracycline
| tetracycline | tetracycline |
|---|---|
tetracycline |
60-54-8 |
Deschlorobiomycin |
Tetracyclinum |
Achromycin |
Tetracyclin |
Sumycin |
Abramycin |
Tsiklomitsin |
Achromycin V |
Liquamycin |
Panmycin |
Tetracyn |
Tetrazyklin |
Ambramycin |
Hostacyclin |
Omegamycin |
Tetradecin |
Tetraverine |
Tsiklomistsin |
Vetacyclinum |
Tetrafil |
Tetracycline base |
Cefracycline |
Criseociclina |
Abricycline |
Agromicina |
Ambramicina |
Biocycline |
Ciclibion |
Copharlan |
Democracin |
Lexacycline |
Limecycline |
Mericycline |
Micycline |
Orlycycline |
Polycycline |
Polyotic |
Purocyclina |
Roviciclina |
Solvocin |
Tetrabon |
Tetracycl |
Amycin |
Veracin |
SK-Tetracycline |
Tetracycline II |
Tetra-Co |
Tetracyclinehydrate |
UNII-F8VB5M810T |
Cyclomycin |
Sustamycin |
Sumycin syrup |
Tetracycline I |
Bio-tetra |
(4S,4aS,5aS,6S,12aS)-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide |
CHEBI:27902 |
Piracaps (base) |
Centet (base) |
Polycycline (VAN) |
2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, (4S,4aS,5aS,6S,12aS)- |
Cefracycline suspension |
Liquamycin (Veterinary) |
Polycycline (antibiotic) |
F8VB5M810T |
(4S,4aS,5aS,12aS)-4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide |
Tetraciclina |
Tetracycline (internal use) |
Supramycin |
Vetquamycin-324 (free base) |
MFCD00151232 |
60-54-8 (FREE BASE) |
NSC-108579 |
E701 |
Achromycin (naphthacene derivative) |
NSC 108579 |
T-125 |
HSDB 3188 |
6-Methyl-1,11-dioxy-2-naphthacenecarboxamide |
Tetracyclinum INN-Latin |
Tetraciclina INN-Spanish |
(4S,4aS,5aS,6S,12aR)-4-(dimethylamino)-1,6,10,11,12a-pentahydroxy-6-methyl-3,12-dioxo-4,4a,5,5a-tetrahydrotetracene-2-carboxamide |
Sumycin (TN) |
2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, (4S-(4alpha,4aalpha,5aalpha,6beta,12aalpha))- |
6416-04-2 (3H2O) |
Economycin |
Vetquamycin |
Brodspec |
Tetracycline (JAN/USP/INN) |
CCRIS 9483 |
SR-01000000212 |
NSC108579 |
Tetrabid Organon |
Ala-Tet |
Tetracycline USP:INN:BAN:JAN |
2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo- |
EINECS 200-481-9 |
Spectrum_001034 |
Tetracycline, EP grade |
Prestwick0_000140 |
Prestwick1_000140 |
Prestwick2_000140 |
Prestwick3_000140 |
Spectrum2_001329 |
Spectrum3_000565 |
Spectrum4_000352 |
Spectrum5_001112 |
DSSTox_CID_3645 |
EC 200-481-9 |
SCHEMBL3098 |
DSSTox_RID_77127 |
DSSTox_GSID_23645 |
BSPBio_000220 |
BSPBio_001950 |
KBioGR_000783 |
KBioSS_001514 |
BIDD:GT0653 |
DivK1c_000827 |
SCHEMBL537050 |
SPBio_001457 |
SPBio_002159 |
BPBio1_000242 |
SCHEMBL2116649 |
SCHEMBL2116661 |
DTXSID7023645 |
SCHEMBL21271987 |
GTPL10927 |
KBio1_000827 |
KBio2_001514 |
KBio2_004082 |
KBio2_006650 |
KBio3_001450 |
NINDS_000827 |
HMS2090B04 |
Tetracycline, >=98.0% (NT) |
HY-A0107 |
RKL10088 |
Tetracycline, >=88.0% (HPLC) |
Tox21_300150 |
BDBM50237605 |
s4490 |
ZINC84441937 |
AKOS024277860 |
AKOS026749977 |
ZINC100303069 |
ZINC102229720 |
CS-8188 |
DB00759 |
MCULE-3752961261 |
CAS-60-54-8 |
IDI1_000827 |
NCGC00017323-03 |
NCGC00017323-04 |
NCGC00017323-05 |
NCGC00017323-07 |
NCGC00017323-15 |
NCGC00142507-02 |
NCGC00254063-01 |
4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,1 0,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide |
BT166207 |
ST019403 |
SBI-0051530.P003 |
1369-EP2269978A2 |
1369-EP2269985A2 |
1369-EP2269991A2 |
1369-EP2270008A1 |
1369-EP2275420A1 |
1369-EP2284150A2 |
1369-EP2284151A2 |
1369-EP2284152A2 |
1369-EP2284153A2 |
1369-EP2284155A2 |
1369-EP2284156A2 |
1369-EP2284164A2 |
1369-EP2287140A2 |
1369-EP2287148A2 |
1369-EP2287150A2 |
1369-EP2289871A1 |
1369-EP2289891A2 |
1369-EP2292088A1 |
1369-EP2292590A2 |
1369-EP2292612A2 |
1369-EP2292617A1 |
1369-EP2295402A2 |
1369-EP2295419A2 |
1369-EP2298732A1 |
1369-EP2301534A1 |
1369-EP2301912A2 |
1369-EP2301913A1 |
1369-EP2301914A1 |
1369-EP2301916A2 |
1369-EP2305637A2 |
1369-EP2305640A2 |
1369-EP2305662A1 |
1369-EP2307027A1 |
1369-EP2308832A1 |
1369-EP2308863A1 |
1369-EP2308883A1 |
1369-EP2311451A1 |
1369-EP2311796A1 |
1369-EP2311797A1 |
1369-EP2311798A1 |
1369-EP2311799A1 |
1369-EP2311822A1 |
1369-EP2314583A1 |
1369-EP2316450A1 |
1369-EP2371797A1 |
1369-EP2371798A1 |
1369-EP2371800A1 |
1369-EP2371804A1 |
C06570 |
D00201 |
AB00053550-04 |
AB00053550_05 |
AB00053550_06 |
Q193045 |
SR-01000000212-3 |
Z2144222809 |
(4S,4aS,5aS,6S,12aS)-2-Amino(hydroxy)methylene-4beta-(dimethylamino)-1,2,3,4,4a,5,5a,6,11,12a-decahydro-6alpha,10,12,12abeta-tetrahydroxy-6-methylnaphthacene-1,3,11-trione |
(4S,4aS,5aS,6S,12aS)-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-4,4a,5,5a-tetrahydrotetracene-2-carboxamide |
(4S,6S,12aS,4aS,5aS)-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,1 1-dioxo-4,5,6,12a,4a,5a-hexahydronaphthacene-2-carboxamide |
Experimental Data
tetracycline
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 0.1 | mM | Unclear | N2 | 33683565 |
Experimental Data Visualization
tetracycline
Statistics Data
tetracycline
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 1 | 1 |
Statistics Data Visualization
tetracycline
