Compound Summary
Compound Information
thioridazine
Compound Name: | thioridazine |
Compound CID: | 5452 |
Synonyms: | thioridazine 50-52-2 Mellaril Thioridazin Melleril More... |
Iupac Name: | 10-[2-(1-methylpiperidin-2-yl)ethyl]-2-methylsulfanylphenothiazine |
InChI: | InChI=1S/C21H26N2S2/c1-22-13-6-5-7-16(22)12-14-23-18-8-3-4-9-20(18)25-21-11-10-17(24-2)15-19(21)23/h3-4,8-11,15-16H,5-7,12-14H2,1-2H3 |
InChIKey: | KLBQZWRITKRQQV-UHFFFAOYSA-N |
Canonical Smiles: | CN1CCCCC1CCN2C3=CC=CC=C3SC4=C2C=C(C=C4)SC |
Isomeric Smiles: | CN1CCCCC1CCN2C3=CC=CC=C3SC4=C2C=C(C=C4)SC |
Molecular Weight: | 370.6 |
Molecular Formula: | C21H26N2S2 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
thioridazine
Molecular Weight: | 370.6 |
Molecular Formula: | C21H26N2S2 |
Hydrogen Bond Donor Count: | 0 |
Hydrogen Bond Acceptor Count: | 4 |
Rotatable Bond Count: | 4 |
Heavy Atom Count: | 25 |
Complexity: | 432 |
Synonyms
thioridazine
| thioridazine | thioridazine |
|---|---|
thioridazine |
50-52-2 |
Mellaril |
Thioridazin |
Melleril |
Meleril |
Malloryl |
Sonapax |
Mellaril-S |
Mallorol |
Mellerets |
Mellerette |
Melleretten |
dl-Thioridazine |
Tioridazina |
TP-21 |
Melleril (liquid) |
Thioridazinum |
10-(2-(1-Methylpiperidin-2-yl)ethyl)-2-(methylthio)-10H-phenothiazine |
Orsanil |
2-Methylmercapto-10-(2-(N-methyl-2-piperidyl)ethyl)phenothiazine |
3-Methylmercapto-N-(2-(N-methyl-2-piperidyl)ethyl)phenothiazine |
10-2-(1-methylpiperidin-2-yl)ethyl-2-methylsulfanylphenothiazine |
Melleryl |
CHEMBL479 |
10-(2-(1-Methyl-2-piperidyl)ethyl)-2-(methylthio)phenothiazine |
10-2-(1-methyl-2-piperidyl)ethyl-2-methylsulfanyl-phenothiazine |
10-2-(1-methylpiperidin-2-yl)ethyl-2-(methylsulfanyl)-10H-phenothiazine |
10H-Phenothiazine, 10-(2-(1-methyl-2-piperidinyl)ethyl)-2-(methylthio)- |
CHEBI:9566 |
NCGC00016059-05 |
(+-)-Thioridazine |
Mellarit |
Thiozine |
Malloryl; Meleril; Mellaril S; Mellerets |
Phenothiazine, 10-((1-methyl-2-piperidyl)ethyl)-2-(methylthio)- |
Thioridazine prolongatum |
DSSTox_CID_3656 |
10H-Phenothiazine, 10-2-(1-methyl-2-piperidinyl)ethyl-2-(methylthio)- |
DSSTox_RID_77130 |
DSSTox_GSID_23656 |
Thioridazinum INN-Latin |
Tioridazina INN-Spanish |
Thioxidazine |
Thioridazine, prolongatum |
Phenothiazine, 10-2-(1-methyl-2-piperidyl)ethyl-2-(methylthio)- |
10-2-(1-methylpiperidin-2-yl)ethyl-2-(methylthio)-10H-phenothiazine |
CAS-50-52-2 |
Mellaril-S (TN) |
NSC186060 |
HSDB 3189 |
C21H26N2S2 |
EINECS 200-044-2 |
Thioridazine (USP/INN) |
Mellaril (*Hydrochloride*) |
AI3-51923 |
Thioridazine USAN:USP:INN:BAN |
Mellaril (Salt/Mix) |
Spectrum_001066 |
Prestwick0_000078 |
Prestwick1_000078 |
Prestwick2_000078 |
Prestwick3_000078 |
Spectrum2_001332 |
Spectrum3_000585 |
Spectrum4_000356 |
Spectrum5_001062 |
(.+/-.)-Thioridazine |
Biomol-NT_000017 |
SCHEMBL9566 |
Lopac0_001252 |
BSPBio_000295 |
BSPBio_002030 |
GTPL100 |
KBioGR_000791 |
KBioGR_002308 |
KBioSS_001546 |
KBioSS_002310 |
DivK1c_000066 |
SPBio_001483 |
SPBio_002216 |
BPBio1_000325 |
BPBio1_001175 |
DTXSID6023656 |
SCHEMBL12434241 |
KBio1_000066 |
KBio2_001546 |
KBio2_002308 |
KBio2_004114 |
KBio2_004876 |
KBio2_006682 |
KBio2_007444 |
KBio3_001530 |
KBio3_002788 |
cMAP_000015 |
NINDS_000066 |
HMS2090J04 |
BCP19922 |
Tox21_110294 |
6960AB |
BDBM50002338 |
NS-835 |
10-2-(1-Methyl-2-piperidinyl)ethyl-2-(methylsulfanyl)-10H-phenothiazine |
Tox21_110294_1 |
CCG-205326 |
DB00679 |
MCULE-7796139302 |
SDCCGSBI-0051219.P005 |
IDI1_000066 |
NCGC00016059-03 |
NCGC00016059-04 |
NCGC00016059-07 |
NCGC00016059-08 |
NCGC00016059-09 |
NCGC00016059-10 |
NCGC00016059-11 |
NCGC00016059-13 |
NCGC00016059-14 |
NCGC00016059-24 |
NCGC00089809-02 |
NCGC00089809-03 |
AS-77485 |
SBI-0051219.P004 |
AB00053553 |
1452-EP2272537A2 |
1452-EP2275420A1 |
1452-EP2298776A1 |
D00373 |
D94995 |
Q58375 |
AB00053553-16 |
AB00053553_17 |
AB00053553_18 |
242T875 |
L001321 |
BRD-A84481105-003-17-2 |
10-2-(1-methyl-2-piperidinyl)ethyl-2-(methylthio)-10h-phenothiazine |
10-2-(1-methyl-piperidin-2-yl)-ethyl-2-methylsulfanyl-10h-phenothiazine |
10H-Phenothiazine, 10-2-(1-methyl-2-piperidyl)ethyl-2-methylthio- |
(Thioridazine)10-2-(1-Methyl-piperidin-2-yl)-ethyl-2-methylsulfanyl-10H-phenothiazine |
10-2-(1-Methyl-2-piperidinyl)ethyl-2-(methylsulfanyl)-10H-phenothiazine # |
10-2-(1-Methyl-piperidin-2-yl)-ethyl-2-methylsulfanyl-10H-phenothiazine (thioridazine) |
Thioridazine solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material |
107388-89-6 |
Experimental Data
thioridazine
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Drosophila melanogaster | 200 | umol/L | 44.01 | 51.12 | 16.16 | S | MALES | 33008901 | Active | ||||
| Drosophila melanogaster | 20 | umol/L | 48.86 | 51.34 | 5.078 | NS | FEMALES | 33008901 | Inactive |
Experimental Data Visualization
thioridazine
Statistics Data
thioridazine
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Drosophila melanogaster | 16.16 | 1 | 2 |
Statistics Data Visualization
thioridazine
