Compound Summary
Compound Information
enalapril
Compound Name: | enalapril |
Compound CID: | 5388962 |
Synonyms: | enalapril 75847-73-3 Vasotec Enalaprilum Enalaprila More... |
Iupac Name: | (2S)-1-[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]pyrrolidine-2-carboxylic acid |
InChI: | InChI=1S/C20H28N2O5/c1-3-27-20(26)16(12-11-15-8-5-4-6-9-15)21-14(2)18(23)22-13-7-10-17(22)19(24)25/h4-6,8-9,14,16-17,21H,3,7,10-13H2,1-2H3,(H,24,25)/t14-,16-,17-/m0/s1 |
InChIKey: | GBXSMTUPTTWBMN-XIRDDKMYSA-N |
Canonical Smiles: | CCOC(=O)C(CCC1=CC=CC=C1)NC(C)C(=O)N2CCCC2C(=O)O |
Isomeric Smiles: | CCOC(=O)[C@H](CCC1=CC=CC=C1)N[C@@H](C)C(=O)N2CCC[C@H]2C(=O)O |
Molecular Weight: | 376.4 |
Molecular Formula: | C20H28N2O5 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
enalapril
Molecular Weight: | 376.4 |
Molecular Formula: | C20H28N2O5 |
Hydrogen Bond Donor Count: | 2 |
Hydrogen Bond Acceptor Count: | 6 |
Rotatable Bond Count: | 10 |
Heavy Atom Count: | 27 |
Complexity: | 519 |
Synonyms
enalapril
| enalapril | enalapril |
|---|---|
enalapril |
75847-73-3 |
Vasotec |
Enalaprilum |
Enalaprila |
Lexxel |
Enalaprilum INN-Latin |
Enalaprila INN-Spanish |
UNII-69PN84IO1A |
CHEMBL578 |
Bonuten |
69PN84IO1A |
CHEBI:4784 |
(S)-1-(N-(1-(Ethoxycarbonyl)-3-phenylpropyl)-L-alanyl)-L-proline |
C20H28N2O5 |
1-(N-((S)-1-Carboxy-3-phenylpropyl)-L-alanyl)-L-proline 1-ethyl ester |
NCGC00021569-04 |
((S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl)-L-alanyl-L-proline |
Enalapril Richet |
DSSTox_CID_2982 |
MK-421 |
DSSTox_RID_76817 |
DSSTox_GSID_22982 |
(2S)-1-(2S)-2-(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-ylaminopropanoylpyrrolidine-2-carboxylic acid |
(S)-1-{(S)-2-1-((S)-Ethoxycarbonyl)-3-phenyl-propylamino-propionyl}-pyrrolidine-2-carboxylic acid |
Gadopril |
Epaned |
L-Proline, N-(1S)-1-(ethoxycarbonyl)-3-phenylpropyl-L-alanyl- |
HSDB 6529 |
Enalapril (INN) |
Enalapril (TN) |
(2S)-1-(2S)-2-{(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-ylamino}propanoylpyrrolidine-2-carboxylic acid |
CAS-75847-73-3 |
Enalapril INN:BAN |
analapril |
Enaladex |
L-Proline, N-((1S)-1-(ethoxycarbonyl)-3-phenylpropyl)-L-alanyl- |
C09AA02 |
Enalapril, AldrichCPR |
Spectrum_001307 |
SCHEMBL18 |
N-(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl-L-alanyl-L-proline |
Prestwick3_000314 |
Spectrum2_001455 |
Spectrum3_001478 |
Spectrum4_000008 |
Spectrum5_001107 |
Enalapril Maleate Usp Xxi |
BSPBio_000308 |
BSPBio_003035 |
KBioGR_000355 |
KBioSS_001787 |
BIDD:GT0751 |
DivK1c_000408 |
SPBio_001349 |
BPBio1_000340 |
GTPL6322 |
DTXSID5022982 |
KBio1_000408 |
KBio2_001787 |
KBio2_004355 |
KBio2_006923 |
KBio3_002535 |
NINDS_000408 |
HMS2090E08 |
HY-B0331 |
ZINC3791297 |
Tox21_110872 |
BDBM50017129 |
N-{(1S)-1-(ethyloxy)carbonyl-3-phenylpropyl}-L-alanyl-L-proline |
AKOS025310615 |
L-Proline, 1-(N-(1-(ethoxycarbonyl)-3-phenylpropyl)-L-alanyl)-, (S)- |
Tox21_110872_1 |
DB00584 |
IDI1_000408 |
NCGC00016932-01 |
NCGC00021569-05 |
NCGC00021569-06 |
NCGC00021569-09 |
K298 |
SBI-0051691.P002 |
CAS-76095-16-4 |
C06977 |
D07892 |
H10947 |
AB00053615-17 |
AB00053615-18 |
AB00053615_19 |
AB00053615_20 |
847E733 |
A838525 |
A838609 |
Q422185 |
BRD-K57545991-050-16-5 |
N-(1(S)-Ethoxycarbonyl-3-phenylpropyl)-L-alanyl-L-proline |
N-1-(S)-ethoxycarbonyl-3-phenylpropyl-L-alanyl-L-proline |
Nalpha -(S)-1-ethoxycarbonyl-3-phenylpropyl-L-alanyl-L-proline |
(s)-1-(n-(1-(ethoxycarbonyl)-3-phenylpropyl)-l-alanyl)-l-proline;Enalapril maleate salt |
(SSS)1-2-(1-Ethoxycarbonyl-3-phenyl-propylamino)-propionyl-pyrrolidine-2-carboxylic acid |
1-2-(1-Ethoxycarbonyl-3-phenyl-propylamino)-propionyl-pyrrolidine-2-carboxylic acid |
(2S)-1-(2S)-2-(1R)-1-ethoxycarbonyl-3-phenyl-propylaminopropanoylpyrrolidine-2-carboxylic acid; maleic acid |
(S)-1-((S)-2-(((S)-1-Ethoxy-1-oxo-4-phenylbutan-2-yl)amino)propanoyl)pyrrolidine-2-carboxylic acid |
(S)-1-((S)-2-((R)-1-ethoxy-1-oxo-4-phenylbutan-2-ylamino)propanoyl)pyrrolidine-2-carboxylic acid |
(S)-1-(R)-2-((R)-1-Ethoxycarbonyl-3-phenyl-propylamino)-propionyl-pyrrolidine-2-carboxylic acid |
(S,S,S)-1-2-(1-Ethoxycarbonyl-3-phenyl-propylamino)-propionyl-pyrrolidine-2-carboxylic acid |
1-2-(1-Ethoxycarbonyl-3-phenyl-propylamino)-propionyl-pyrrolidine-2-carboxylic acid (Enalapril) |
1-2-(1-Ethoxycarbonyl-3-phenyl-propylamino)-propionyl-pyrrolidine-2-carboxylic acid(enalapril) |
2-2-(1-Carboxy-3-phenyl-propylamino)-propionyl-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid(enalapril) |
Experimental Data
enalapril
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Rattus norvegicus | 10 | mg/kg | 735 | 892 | 0.21 | S | MALES | 17557916 | Active |
Experimental Data Visualization
enalapril
Statistics Data
enalapril
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Rattus norvegicus | 0.21 | 1 | 1 |
Statistics Data Visualization
enalapril
