Compound Summary
Compound Information
Tyrphostin AG 808
Compound Name: | Tyrphostin AG 808 |
Compound CID: | 5329275 |
Synonyms: | Tyrphostin AG 808 NSC650934 AG-808 Tyrphostin AG-808 Lopac-T-5318 More... |
Iupac Name: | (E)-2-(3,4-dihydroxybenzoyl)-3-(1H-indol-3-yl)prop-2-enenitrile |
InChI: | InChI=1S/C18H12N2O3/c19-9-12(18(23)11-5-6-16(21)17(22)8-11)7-13-10-20-15-4-2-1-3-14(13)15/h1-8,10,20-22H/b12-7+ |
InChIKey: | TTZDOBVWBQXGDC-KPKJPENVSA-N |
Canonical Smiles: | C1=CC=C2C(=C1)C(=CN2)C=C(C#N)C(=O)C3=CC(=C(C=C3)O)O |
Isomeric Smiles: | C1=CC=C2C(=C1)C(=CN2)/C=C(\C#N)/C(=O)C3=CC(=C(C=C3)O)O |
Molecular Weight: | 304.3 |
Molecular Formula: | C18H12N2O3 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
Tyrphostin AG 808
Molecular Weight: | 304.3 |
Molecular Formula: | C18H12N2O3 |
Hydrogen Bond Donor Count: | 3 |
Hydrogen Bond Acceptor Count: | 4 |
Rotatable Bond Count: | 3 |
Heavy Atom Count: | 23 |
Complexity: | 536 |
Synonyms
Tyrphostin AG 808
| Tyrphostin AG 808 | Tyrphostin AG 808 |
|---|---|
Tyrphostin AG 808 |
NSC650934 |
AG-808 |
Tyrphostin AG-808 |
Lopac-T-5318 |
Lopac0_001178 |
CHEMBL68534 |
Indole-Containing Inhibitor 5 |
BDBM5171 |
Tyrphostin AG 808, >=98% |
DTXSID401017668 |
ZINC3927328 |
(E)-2-(3,4-dihydroxybenzoyl)-3-(1H-indol-3-yl)prop-2-enenitrile |
CCG-205252 |
NSC-650934 |
2-Propenenitrile,4-dihydroxy- benzoyl)- |
NCGC00016030-01 |
NCGC00016030-02 |
NCGC00016030-03 |
NCGC00016030-04 |
NCGC00094433-01 |
NCGC00094433-02 |
EU-0101178 |
T 5318 |
SR-01000076162 |
SR-01000076162-1 |
2-(3,4-Dihydroxybenzoyl)-3-(1H-indol-3-yl)acrylonitrile |
2-Propenenitrile, 3-(1H-indol-3-yl)-2-(3,4-dihydroxy- benzoyl)- |
2-Cyano-3-(3\,4\-dihydroxyphenyl)-1-(3"-indolyl)-3-oxo-1-propene |
(2E)-2-(3,4-dihydroxyphenyl)carbonyl-3-(1H-indol-3-yl)prop-2-enenitrile |
(alphaE)-3,4-Dihydroxy-alpha-(1H-indol-3-ylmethylene)-beta-oxobenzenepropanenitrile |
160953-95-7 |
Experimental Data
Tyrphostin AG 808
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33 | umol/L | -2 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
Tyrphostin AG 808
Statistics Data
Tyrphostin AG 808
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | -2 | 1 | 1 |
Statistics Data Visualization
Tyrphostin AG 808
