Compound Summary
Compound Information
Tyrphostin AG 112
Compound Name: | Tyrphostin AG 112 |
Compound CID: | 5328804 |
Synonyms: | Tyrphostin AG 112 Tyrphostin A48 AG 112 144978-82-5 (3Z)-2-amino-3-(4-hydroxyphenyl)methylideneprop-1-ene-1,1,3-tricarbonitrile More... |
Iupac Name: | (3Z)-2-amino-4-(4-hydroxyphenyl)buta-1,3-diene-1,1,3-tricarbonitrile |
InChI: | InChI=1S/C13H8N4O/c14-6-10(13(17)11(7-15)8-16)5-9-1-3-12(18)4-2-9/h1-5,18H,17H2/b10-5+ |
InChIKey: | DXVJRTIPBNBLLB-BJMVGYQFSA-N |
Canonical Smiles: | C1=CC(=CC=C1C=C(C#N)C(=C(C#N)C#N)N)O |
Isomeric Smiles: | C1=CC(=CC=C1/C=C(\C#N)/C(=C(C#N)C#N)N)O |
Molecular Weight: | 236.23 |
Molecular Formula: | C13H8N4O |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
Tyrphostin AG 112
Molecular Weight: | 236.23 |
Molecular Formula: | C13H8N4O |
Hydrogen Bond Donor Count: | 2 |
Hydrogen Bond Acceptor Count: | 5 |
Rotatable Bond Count: | 2 |
Heavy Atom Count: | 18 |
Complexity: | 505 |
Synonyms
Tyrphostin AG 112
| Tyrphostin AG 112 | Tyrphostin AG 112 |
|---|---|
Tyrphostin AG 112 |
Tyrphostin A48 |
AG 112 |
144978-82-5 |
(3Z)-2-amino-3-(4-hydroxyphenyl)methylideneprop-1-ene-1,1,3-tricarbonitrile |
ag112 |
Tyrphostin-48 |
AG-112 |
Tyrphostin Ag-112 |
Lopac-T-6943 |
Lopac0_001140 |
CHEMBL76589 |
GTPL5913 |
SCHEMBL10144540 |
CHEBI:93930 |
HMS3229M17 |
HMS3263D21 |
Tox21_501140 |
2-Amino-4-(4′-hydroxyphenyl)-1,1,3-tricyanobuta-1,3-diene |
HSCI1_000156 |
ZINC15977019 |
(3Z)-2-amino-4-(4-hydroxyphenyl)buta-1,3-diene-1,1,3-tricarbonitrile |
CCG-205214 |
LP01140 |
SDCCGSBI-0051107.P003 |
NCGC00016041-01 |
NCGC00016041-02 |
NCGC00016041-03 |
NCGC00016041-04 |
NCGC00016041-05 |
NCGC00094406-01 |
NCGC00094406-02 |
NCGC00261825-01 |
HY-112474 |
CS-0046102 |
EU-0101140 |
T 6943 |
SR-01000076168 |
J-008034 |
SR-01000076168-1 |
BRD-K01192156-001-01-9 |
Q27074333 |
2-amino-4-(4-hydroxyphenyl)-1,1,3-tricyanobuta-1,3-diene" |
3-Amino-2,4-dicyano-5-(4-hydroxyphenyl)-penta-2,4-dienonitrile |
(3Z)-2-Amino-4-(4-hydroxyphenyl)-1,3-butadiene-1,1,3-tricarbonitrile |
Experimental Data
Tyrphostin AG 112
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33 | umol/L | 3 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
Tyrphostin AG 112
Statistics Data
Tyrphostin AG 112
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 3 | 1 | 1 |
Statistics Data Visualization
Tyrphostin AG 112
