Compound Summary
Compound Information
Tyrphostin AG 835
Compound Name: | Tyrphostin AG 835 |
Compound CID: | 5328769 |
Synonyms: | Tyrphostin AG 835 133550-37-5 Tyrphostin B44, (+) enantiomer TYRPHOSTINAG835 Tyrphostin B50 More... |
Iupac Name: | (E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-[(1S)-1-phenylethyl]prop-2-enamide |
InChI: | InChI=1S/C18H16N2O3/c1-12(14-5-3-2-4-6-14)20-18(23)15(11-19)9-13-7-8-16(21)17(22)10-13/h2-10,12,21-22H,1H3,(H,20,23)/b15-9+/t12-/m0/s1 |
InChIKey: | UMGQVUWXNOJOSJ-DGGAMASNSA-N |
Canonical Smiles: | CC(C1=CC=CC=C1)NC(=O)C(=CC2=CC(=C(C=C2)O)O)C#N |
Isomeric Smiles: | C[C@@H](C1=CC=CC=C1)NC(=O)/C(=C/C2=CC(=C(C=C2)O)O)/C#N |
Molecular Weight: | 308.3 |
Molecular Formula: | C18H16N2O3 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
Tyrphostin AG 835
Molecular Weight: | 308.3 |
Molecular Formula: | C18H16N2O3 |
Hydrogen Bond Donor Count: | 3 |
Hydrogen Bond Acceptor Count: | 4 |
Rotatable Bond Count: | 4 |
Heavy Atom Count: | 23 |
Complexity: | 488 |
Synonyms
Tyrphostin AG 835
| Tyrphostin AG 835 | Tyrphostin AG 835 |
|---|---|
Tyrphostin AG 835 |
133550-37-5 |
Tyrphostin B44, (+) enantiomer |
TYRPHOSTINAG835 |
Tyrphostin B50 |
(E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-(1S)-1-phenylethylprop-2-enamide |
MFCD00209855 |
(2E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-(1S)-1-phenylethylprop-2-enamide |
Tyrphostin Ag-835 |
tyrphostin-AG-835 |
Tocris-0579 |
Tyrphostin deriv. 50 |
Lopac-T-4443 |
Lopac-T-5568 |
Lopac0_001198 |
BDBM4305 |
CHEMBL261557 |
SCHEMBL12856415 |
Tyrphostin AG 835, >=92% |
DTXSID101017645 |
HMS3263P17 |
HMS3266M20 |
HMS3414G21 |
HMS3678G21 |
ZINC2557951 |
Tox21_501198 |
HSCI1_000020 |
(2E)-2-Cyano-3-(3,4-Dihydroxyphenyl)-N-(1S)-1-Phenylethyl-2-Propenamide |
AKOS024458569 |
CCG-205272 |
LP01198 |
SDCCGSBI-0051165.P002 |
NCGC00016022-01 |
NCGC00016022-02 |
NCGC00024663-01 |
NCGC00024663-02 |
NCGC00024663-03 |
NCGC00024663-04 |
NCGC00261883-01 |
AS-73062 |
EU-0101198 |
T3540 |
T 5568 |
SR-01000597624 |
SR-01000597624-1 |
BRD-K17415526-001-02-7 |
(S)-2-cyano-3-(3,4-dihydroxyphenyl)-N-(1-phenylethyl)acrylamide |
(S)-N-(alpha-Methylbenzyl)-3,4-dihydroxybenzylidenecyanoacetamide |
(S,E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-(1-phenylethyl)acrylamide |
2-Cyano-3-(3,4-dihydroxyphenyl)-N-(S)-1-phenylethylacrylamide |
(+)-(S)-N-(alpha-Methylbenzyl)-3,4-dihydroxy-benzylidenecyanoacetamide |
(+)-(S)-N-(alpha-Methylbenzyl)-3,4-dihydroxybenzylidenecyanoacetamide |
(S)-(E)-2-Cyano-3-(3,4-dihydroxyphenyl)-N-(1-phenylethyl)-2-propenamide |
2-Propenamide,2-cyano-3-(3,4-dihydroxyphenyl)-N-(1S)-1-phenylethyl-,(2E)- |
(S)-N-(alpha-Methylbenzyl)-3,4-dihydroxybenzylidenecyanoacetamide / (S)-2-Cyano-3-(3,4-dihydroxyphenyl)-N-(1-phenylethyl)acrylamide |
Experimental Data
Tyrphostin AG 835
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33 | umol/L | 1 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
Tyrphostin AG 835
Statistics Data
Tyrphostin AG 835
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 1 | 1 | 1 |
Statistics Data Visualization
Tyrphostin AG 835
