Compound Summary
Compound Information
kn-93
Compound Name: | kn-93 |
Compound CID: | 5312122 |
Synonyms: | kn-93 139298-40-1 KN 93 Methoxybenzene-sulfonamide KN93 More... |
Iupac Name: | N-[2-[[[(E)-3-(4-chlorophenyl)prop-2-enyl]-methylamino]methyl]phenyl]-N-(2-hydroxyethyl)-4-methoxybenzenesulfonamide |
InChI: | InChI=1S/C26H29ClN2O4S/c1-28(17-5-6-21-9-11-23(27)12-10-21)20-22-7-3-4-8-26(22)29(18-19-30)34(31,32)25-15-13-24(33-2)14-16-25/h3-16,30H,17-20H2,1-2H3/b6-5+ |
InChIKey: | LLLQTDSSHZREGW-AATRIKPKSA-N |
Canonical Smiles: | CN(CC=CC1=CC=C(C=C1)Cl)CC2=CC=CC=C2N(CCO)S(=O)(=O)C3=CC=C(C=C3)OC |
Isomeric Smiles: | CN(C/C=C/C1=CC=C(C=C1)Cl)CC2=CC=CC=C2N(CCO)S(=O)(=O)C3=CC=C(C=C3)OC |
Molecular Weight: | 501 |
Molecular Formula: | C26H29ClN2O4S |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
kn-93
Molecular Weight: | 501 |
Molecular Formula: | C26H29ClN2O4S |
Hydrogen Bond Donor Count: | 1 |
Hydrogen Bond Acceptor Count: | 6 |
Rotatable Bond Count: | 11 |
Heavy Atom Count: | 34 |
Complexity: | 713 |
Synonyms
kn-93
| kn-93 | kn-93 |
|---|---|
kn-93 |
139298-40-1 |
KN 93 |
Methoxybenzene-sulfonamide |
KN93 |
(E)-N-(2-(((3-(4-Chlorophenyl)allyl)(methyl)amino)methyl)phenyl)-N-(2-hydroxyethyl)-4-methoxybenzenesulfonamide |
UNII-2TW744QBU1 |
2TW744QBU1 |
CHEMBL155333 |
N-2-(E)-3-(4-chlorophenyl)prop-2-enyl-methylaminomethylphenyl-N-(2-hydroxyethyl)-4-methoxybenzenesulfonamide |
1188890-40-5 |
N-(2-(((3-(4-Chlorophenyl)-2-propenyl)methylamino)methyl)phenyl)-N-(2-hydroxyethyl)-4-methoxybenzenesulfonamide |
C26H29ClN2O4S |
N-2-3-(4-chlorophenyl)-2-propenylmethylaminomethylphenyl-N-(2-hydroxyethyl)-4-methoxybenzenesulfonamide |
InSolution™ KN-93 |
2-(N-(2-Hydroxyethyl)-N-(4-methoxybenzenesulfonyl))amino-N-(4-chlorocinnamyl)-N-methylbenzylamine |
KN-93(free base) |
BiomolKI_000041 |
n-2-3-(4-chlorophenyl)-2-propenylmethylaminomethylphenyl-n-(2-hydroxyethyl)-4-methoxybenzenesulfonamide phosphate salt |
BiomolKI2_000049 |
BMK1-E5 |
Benzenesulfonamide, N-(2-(((3-(4-chlorophenyl)-2-propenyl)methylamino)methyl)phenyl)-N-(2-hydroxyethyl)-4-methoxy- |
GTPL6002 |
SCHEMBL1983199 |
CHEBI:91460 |
KN-93-H3PO4 |
AOB4249 |
BCPP000193 |
HMS3229K12 |
HMS3648M10 |
EX-A2884 |
3764AH |
BDBM50108799 |
FD5004 |
HSCI1_000371 |
MFCD00236424 |
MFCD03788201 |
s6787 |
ZINC53246208 |
AKOS015994570 |
ACN-048492 |
BCP9000817 |
CCG-100645 |
CS-1095 |
ES-0019 |
NCGC00162399-02 |
NCGC00162399-04 |
2-N-(2-hydroxyethyl)-N-(4-methoxybenzenesulfonyl)amino-N-(4-chlorocinnamyl)-N-methylbenzylamine) |
HY-15465 |
N-2-3-(4-Chlorophenyl)-2-propenylmethylaminomethylphenyl-N-(2-hydroxyethyl)-4-methoxybenzenesulphonamide |
InSolution KN-93 - CAS 139298-40-1 |
A886059 |
SR-01000946389 |
J-007263 |
KN-93 - CAS 139298-40-1 |
SR-01000946389-1 |
BRD-K93480852-001-03-0 |
(2-N -(2-hydroxyethyl)-N -(4-methoxybenzenesulfonyl)amino-N -(4-chlorocinnamyl)-N -methylbenzylamine) |
Benzenesulfonamide, N-2-3-(4-chlorophenyl)-2-propen-1-ylmethylaminomethylphenyl-N-(2-hydroxyethyl)-4-methoxy- |
N-(2-(((4-chlorocinnamyl)(methyl)amino)methyl)phenyl)-N-(2-hydroxyethyl)-4-methoxybenzenesulfonamide |
N-2-({(2E)-3-(4-chlorophenyl)prop-2-en-1-yl(methyl)amino}methyl)phenyl-2-hydroxy-S-(4-methoxyphenyl)ethane-1-sulfonamido |
N-2-({(2E)-3-(4-chlorophenyl)prop-2-en-1-yl(methyl)amino}methyl)phenyl-N-(2-hydroxyethyl)-4-methoxybenzene-1-sulfonamide |
N-2-({(2E)-3-(4-chlorophenyl)prop-2-en-1-yl(methyl)amino}methyl)phenyl-N-(2-hydroxyethyl)-4-methoxybenzenesulfonamide |
N-2-({3-(4-Chloro-phenyl)-allyl-methyl-amino}-methyl)-phenyl-N-(2-hydroxy-ethyl)-4-methoxy-benzenesulfonamide |
N-2-3-(4-Chlorophenyl)-2-propenylmethylaminomethylphenyl-N-(2-hydroxyethyl)-4-methoxybenzenesulphonamide;KN-93 |
N-2-3-(4-chlorophenyl)prop-2-enyl-methylaminomethylphenyl-N-(2-hydroxyethyl)-4-methoxybenzenesulfonamide |
N-2-N-(4-Chlorocinnamyl)-N-methylaminomethylphenyl-N-(2-hydroxyethyl)-4-methoxybenzenesulfonamide phosphate salt |
Experimental Data
kn-93
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Drosophila melanogaster | 20 | S | Oregon-R | 22363408 | Active |
Experimental Data Visualization
kn-93
Statistics Data
kn-93
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Drosophila melanogaster | 20 | 1 | 1 |
Statistics Data Visualization
kn-93
