Compound Summary
Compound Information
AB-MECA
Compound Name: | AB-MECA |
Compound CID: | 5310992 |
Synonyms: | AB-MECA 152918-26-8 (2S,3S,4R,5R)-5-6-(4-aminophenyl)methylaminopurin-9-yl-3,4-dihydroxy-N-methyloxolane-2-carboxamide AB-MECA, solid 3HAB-MECA More... |
Iupac Name: | (2S,3S,4R,5R)-5-[6-[(4-aminophenyl)methylamino]purin-9-yl]-3,4-dihydroxy-N-methyloxolane-2-carboxamide |
InChI: | InChI=1S/C18H21N7O4/c1-20-17(28)14-12(26)13(27)18(29-14)25-8-24-11-15(22-7-23-16(11)25)21-6-9-2-4-10(19)5-3-9/h2-5,7-8,12-14,18,26-27H,6,19H2,1H3,(H,20,28)(H,21,22,23)/t12-,13+,14-,18+/m0/s1 |
InChIKey: | LDYMCRRFCMRFKB-MOROJQBDSA-N |
Canonical Smiles: | CNC(=O)C1C(C(C(O1)N2C=NC3=C(N=CN=C32)NCC4=CC=C(C=C4)N)O)O |
Isomeric Smiles: | CNC(=O)[C@@H]1[C@H]([C@H]([C@@H](O1)N2C=NC3=C(N=CN=C32)NCC4=CC=C(C=C4)N)O)O |
Molecular Weight: | 399.4 |
Molecular Formula: | C18H21N7O4 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
AB-MECA
Molecular Weight: | 399.4 |
Molecular Formula: | C18H21N7O4 |
Hydrogen Bond Donor Count: | 5 |
Hydrogen Bond Acceptor Count: | 9 |
Rotatable Bond Count: | 5 |
Heavy Atom Count: | 29 |
Complexity: | 576 |
Synonyms
AB-MECA
| AB-MECA | AB-MECA |
|---|---|
AB-MECA |
152918-26-8 |
(2S,3S,4R,5R)-5-6-(4-aminophenyl)methylaminopurin-9-yl-3,4-dihydroxy-N-methyloxolane-2-carboxamide |
AB-MECA, solid |
3HAB-MECA |
GTPL416 |
SCHEMBL16585151 |
BDBM21242 |
DTXSID70415501 |
ZINC4475069 |
CS-5220 |
NCGC00162075-01 |
NCGC00162075-02 |
NCGC00162075-03 |
NCGC00162075-06 |
HY-19365 |
J-008959 |
Q27074104 |
5-Methylamino-N-(4-aminobenzyl)-5-oxo-5-deoxyadenosine |
N(6)-(4-amino-3-iodobenzyl)adenosine-5-N-methyluronamide |
5-6-(4-aminophenyl)methylaminopurin-9-yl-3,4-dihydroxy-N-methyloxolane-2-carboxamide |
Adenosine, N(6)-4-aminobenzyl-4-N-methylcarbamoyl-4-dehydroxymethyl- |
(2S,3S,4R,5R)-5-(6-{(4-aminophenyl)methylamino}-9H-purin-9-yl)-3,4-dihydroxy-N-methyloxolane-2-carboxamide |
Experimental Data
AB-MECA
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33 | umol/L | 10 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
AB-MECA
Statistics Data
AB-MECA
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 10 | 1 | 1 |
Statistics Data Visualization
AB-MECA
