Compound Summary
Compound Information
Phenoxybenzamine hydrochloride
Compound Name: | Phenoxybenzamine hydrochloride |
Compound CID: | 5284441 |
Synonyms: | Phenoxybenzamine hydrochloride 63-92-3 Phenoxybenzamine Hcl Dibenzyline N-benzyl-N-(2-chloroethyl)-1-phenoxypropan-2-amine hydrochloride More... |
Iupac Name: | N-benzyl-N-(2-chloroethyl)-1-phenoxypropan-2-amine;hydrochloride |
InChI: | InChI=1S/C18H22ClNO.ClH/c1-16(15-21-18-10-6-3-7-11-18)20(13-12-19)14-17-8-4-2-5-9-17;/h2-11,16H,12-15H2,1H3;1H |
InChIKey: | VBCPVIWPDJVHAN-UHFFFAOYSA-N |
Canonical Smiles: | CC(COC1=CC=CC=C1)N(CCCl)CC2=CC=CC=C2.Cl |
Isomeric Smiles: | CC(COC1=CC=CC=C1)N(CCCl)CC2=CC=CC=C2.Cl |
Molecular Weight: | 340.3 |
Molecular Formula: | C18H23Cl2NO |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
Phenoxybenzamine hydrochloride
Molecular Weight: | 340.3 |
Molecular Formula: | C18H23Cl2NO |
Hydrogen Bond Donor Count: | 1 |
Hydrogen Bond Acceptor Count: | 2 |
Rotatable Bond Count: | 8 |
Heavy Atom Count: | 22 |
Complexity: | 262 |
Synonyms
Phenoxybenzamine hydrochloride
| Phenoxybenzamine hydrochloride | Phenoxybenzamine hydrochloride |
|---|---|
Phenoxybenzamine hydrochloride |
63-92-3 |
Phenoxybenzamine Hcl |
Dibenzyline |
N-benzyl-N-(2-chloroethyl)-1-phenoxypropan-2-amine hydrochloride |
Dibenzyline hydrochloride |
Phenoxybenzamine (hydrochloride) |
Bensylyt NEN |
Dibenzyran |
NCI-C01661 |
Phenoxybenzamine chloride |
MLS000069374 |
CHEBI:8078 |
NSC 37448 |
MFCD00055152 |
63-92-3 (HCl) |
2-(N-Benzyl-2-chloroethylamino)-1-phenoxypropane hydrochloride |
SMR000058422 |
N-(2-Chloroethyl)-N-(1-methyl-2-phenoxyethyl)benzylamine hydrochloride |
N-benzyl-N-(2-chloroethyl)-1-phenoxypropan-2-amine;hydrochloride |
DSSTox_CID_1127 |
N-(2-Chloroethyl)-N-(1-methyl-2-phenoxyethyl)benzenemethanamine hydrochloride |
Benzenemethanamine, N-(2-chloroethyl)-N-(1-methyl-2-phenoxyethyl)-,hydrochloride |
DSSTox_RID_75958 |
DSSTox_GSID_21127 |
N-2-Phenoxyisopropyl-N-benzyl-chloroethylamine hydrochloride |
Phenoxybenzamine.HCl |
Benzyl(2-chloroethyl)(1-methyl-2-phenoxyethyl)amine hydrochloride |
Phenoxybenzamine hydrochloride (USP) |
SR-01000000017 |
C18H23Cl2NO |
Dibenzylene |
Dibenzyline (TN) |
POB HCl |
CPD000058422 |
Opera_ID_300 |
CAS-63-92-3 |
SCHEMBL50729 |
BENSYLYTE HYDROCHLORIDE |
MLS002222313 |
Phenyoxybenzamine hydrochloride |
SPECTRUM2300176 |
CHEMBL1200787 |
DTXSID0021127 |
HY-B0431A |
AOB5790 |
HMS1570N10 |
Pharmakon1600-02300176 |
Phenoxybenzamine Hydrochloride,(S) |
BCP28467 |
NSC37448 |
Tox21_201588 |
Tox21_302978 |
WLN: G2N1R&Y1&1OR &GH |
CCG-39614 |
NSC-37448 |
NSC759572 |
AKOS015966790 |
N-(2-Chloroethyl)-N-(1-methyl-2-phenoxyethyl)-benzylamine Hydrochloride |
AC-8077 |
LP00235 |
MCULE-2455465785 |
NC00598 |
NSC-759572 |
NCGC00089748-02 |
NCGC00089748-06 |
NCGC00093699-01 |
NCGC00093699-02 |
NCGC00093699-03 |
NCGC00093699-04 |
NCGC00256370-01 |
NCGC00259137-01 |
AS-16927 |
H533 |
AB0013102 |
DB-054579 |
B-019 |
D0158 |
EU-0100235 |
FT-0603264 |
FT-0673569 |
FT-0673570 |
N-benzyl-N-(2-chloroethyl)-1-phenoxypropan |
S2499 |
SW197327-3 |
EN300-52514 |
C07436 |
D00507 |
Phenoxybenzamine hydrochloride, >=97%, powder |
055P152 |
J-009731 |
SR-01000000017-2 |
SR-01000000017-6 |
Q27107723 |
N-Phenoxyisopropyl-N-benzyl-2-chloroethylamine Hydrochloride |
N-benzyl-N-(2-chloroethyl)-1-phenoxypropan-2-amine;hydron;chloride |
N-(2-Chloroethyl)-N-(1-methyl-2-phenoxyethyl)benzylamine, hydrochloride |
BENZENEMETHANAMINE, N-(2-CHLOROETHYL)-N-(1-METHYL-2-PHENOXYETHYL)-,HCL |
Phenoxybenzamine hydrochloride, United States Pharmacopeia (USP) Reference Standard |
Phenoxybenzamine HCl pound>>NCI-C01661 pound>> NCI C01661 pound>> NCIC01661 pound>>NSC 37448 pound>>NSC37448 pound>>NSC-37448 |
Phenoxybenzamine Hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material |
Experimental Data
Phenoxybenzamine hydrochloride
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Drosophila melanogaster | 200 | umol/L | 43.17 | 45.43 | 5.23 | NS | MALES | 33008901 | Inactive | ||||
| Drosophila melanogaster | 20 | umol/L | 44.63 | 45.32 | 1.55 | NS | FEMALES | 33008901 | Inactive | ||||
| Caenorhabditis elegans | 33 | umol/L | -4 | NS | N2 | 24134630 | Inactive | ||||||
| Caenorhabditis elegans | 100 | umol/L | 16 | 16.64 | 4.003 | NS | N2 | 33008901 | Inactive | ||||
| Caenorhabditis elegans | 10 | umol/L | 17.37 | 16.53 | -4.847 | NS | N2 | 33008901 | Inactive |
Experimental Data Visualization
Phenoxybenzamine hydrochloride
Statistics Data
Phenoxybenzamine hydrochloride
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 4.003 | 2 | 3 | |
| Drosophila melanogaster | 5.23 | 1 | 2 |
Statistics Data Visualization
Phenoxybenzamine hydrochloride
