Compound Summary
Compound Information
tranilast
Compound Name: | tranilast |
Compound CID: | 5282230 |
Synonyms: | tranilast 53902-12-8 trans-Tranilast Rizaben 70806-55-2 More... |
Iupac Name: | 2-[[(E)-3-(3,4-dimethoxyphenyl)prop-2-enoyl]amino]benzoic acid |
InChI: | InChI=1S/C18H17NO5/c1-23-15-9-7-12(11-16(15)24-2)8-10-17(20)19-14-6-4-3-5-13(14)18(21)22/h3-11H,1-2H3,(H,19,20)(H,21,22)/b10-8+ |
InChIKey: | NZHGWWWHIYHZNX-CSKARUKUSA-N |
Canonical Smiles: | COC1=C(C=C(C=C1)C=CC(=O)NC2=CC=CC=C2C(=O)O)OC |
Isomeric Smiles: | COC1=C(C=C(C=C1)/C=C/C(=O)NC2=CC=CC=C2C(=O)O)OC |
Molecular Weight: | 327.3 |
Molecular Formula: | C18H17NO5 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
tranilast
Molecular Weight: | 327.3 |
Molecular Formula: | C18H17NO5 |
Hydrogen Bond Donor Count: | 2 |
Hydrogen Bond Acceptor Count: | 5 |
Rotatable Bond Count: | 6 |
Heavy Atom Count: | 24 |
Complexity: | 464 |
Synonyms
tranilast
| tranilast | tranilast |
|---|---|
tranilast |
53902-12-8 |
trans-Tranilast |
Rizaben |
70806-55-2 |
Tranilastum |
MK 341 |
Tranilast trans- |
N-(3,4-Dimethoxycinnamoyl)anthranilic acid |
UNII-HVF50SMY6E |
SB-252218 |
MK-341 |
(E)-2-(3-(3,4-dimethoxyphenyl)acrylamido)benzoic acid |
Tranilast (SB 252218) |
3,4-DAA |
HVF50SMY6E |
2-(E)-3-(3,4-dimethoxyphenyl)prop-2-enoylaminobenzoic acid |
MLS000028468 |
CHEBI:77572 |
2-((3-(3,4-Dimethoxyphenyl)-1-oxo-2-propenyl)amino)benzoic acid |
MFCD00864787 |
NCGC00018185-05 |
SMR000058373 |
2-3-(3,4-Dimethoxyphenyl)-1-oxo-2-propenylaminobenzoic Acid |
2-{(2e)-3-(3,4-Dimethoxyphenyl)prop-2-Enoylamino}benzoic Acid |
(E)-2-3-(3,4-Dimethoxyphenyl)-1-oxo-2-propenylaminobenzoic acid |
Tranilastum INN-Latin |
2-(3-(3,4-dimethoxyphenyl)acrylamido)benzoic acid |
Tranilast USAN:INN:JAN |
2-(2E)-3-(3,4-dimethoxyphenyl)prop-2-enamidobenzoic acid |
Tranpro |
2-3-(3,4-dimethoxyphenyl)-1-oxoprop-2-enylaminobenzoic acid |
2-({(2E)-3-3,4-bis(methyloxy)phenylprop-2-enoyl}amino)benzoic acid |
Rizaben (TN) |
SR-01000003092 |
n-(3,4-dimethoxycinnamoyl) anthranilic acid |
BENZOIC ACID, 2-((3-(3,4-DIMETHOXYPHENYL)-1-OXO-2-PROPENYL)AMINO)- |
Anthranilic acid, N-(3,4-dimethoxycinnamoyl)- |
Tranilast- Bio-X |
NU-3450 |
SB 252218 |
Opera_ID_1657 |
DSSTox_CID_3693 |
T 0318 |
DSSTox_RID_77152 |
DSSTox_GSID_23693 |
Lopac0_001193 |
SCHEMBL29875 |
BSPBio_003561 |
ZINC797 |
53902-17-3 |
MLS000759509 |
MLS001065902 |
MLS001077269 |
MLS001424045 |
MLS002207030 |
MLS006010043 |
SPECTRUM1505333 |
CHEMBL415324 |
GTPL6326 |
Tranilast (JP17/USAN/INN) |
Benzoic acid, 2-3-(3,4-dimethoxyphenyl)-1-oxo-2-propenylamino- |
DTXSID7023693 |
BDBM21613 |
CHEBI:92320 |
AOB5086 |
N-(3′,4′-Dimethoxycinnamoyl)anthranilic Acid |
HMS2051F05 |
HMS2089L07 |
HMS2094I21 |
HMS2230F18 |
HMS3263P07 |
HMS3412G17 |
HMS3648A16 |
HMS3676G17 |
HMS3713J04 |
Pharmakon1600-01505333 |
(2-Phenylthiazol-5-yl)methylamine |
AMY14167 |
BCP06359 |
BCP15888 |
HY-B0195 |
Tox21_110836 |
Tox21_501193 |
2-3-(3,4-Dimethoxyphenyl)-1-oxo-2-propenylamino benzoic acid |
AC-940 |
CCG-39992 |
HSCI1_000076 |
NSC758970 |
s5871 |
SBB052710 |
AKOS002841076 |
Tranilast, >=98% (HPLC), powder |
DB07615 |
KS-1193 |
LP01193 |
NC00171 |
NSC 758970 |
NSC-758970 |
SDCCGSBI-0051160.P004 |
NCGC00018185-04 |
NCGC00018185-06 |
NCGC00018185-08 |
NCGC00018185-09 |
NCGC00018185-10 |
NCGC00018185-20 |
NCGC00018185-23 |
NCGC00018185-26 |
NCGC00021458-04 |
NCGC00021458-05 |
NCGC00021458-07 |
NCGC00261878-01 |
BD164491 |
I586 |
SB252218 |
SBI-0051160.P003 |
AB0013774 |
CAS-53902-12-8 |
EU-0101193 |
S1439 |
SW197551-3 |
N-(3 ,4 -dimethoxycinnamoyl)anthranilic acid |
D02027 |
AB00382987-18 |
AB00382987-19 |
AB00382987_21 |
902T173 |
A829819 |
A923780 |
2-(3,4-Dimethoxy-trans-cinnamoylamino)benzoic acid |
Q-201849 |
Q2325594 |
SR-01000003092-2 |
SR-01000003092-4 |
SR-01000003092-9 |
BRD-K17849083-001-02-2 |
BRD-K17849083-001-03-0 |
BRD-K19533706-001-01-9 |
Q27164069 |
SR-01000003092-16 |
2-3-(3,4-Dimethoxyphenyl)-acryloylamino-benzoic acid |
2-3-(3,4-dimethoxyphenyl)prop-2-enoylaminobenzoic acid |
2-(2E)-3-(3,4-dimethoxyphenyl)prop-2-enoylaminobenzoic acid |
2-3-(3,4-Dimethoxyphenyl)-1-oxo-2-propen-1-ylaminobenzoic Acid |
D27 |
Experimental Data
tranilast
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33 | umol/L | -6 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
tranilast
Statistics Data
tranilast
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | -6 | 1 | 1 |
Statistics Data Visualization
tranilast
