Compound Summary
Compound Information
genistein
Compound Name: | genistein |
Compound CID: | 5280961 |
Synonyms: | genistein 446-72-0 Prunetol Genisterin 4,5,7-Trihydroxyisoflavone More... |
Iupac Name: | 5,7-dihydroxy-3-(4-hydroxyphenyl)chromen-4-one |
InChI: | InChI=1S/C15H10O5/c16-9-3-1-8(2-4-9)11-7-20-13-6-10(17)5-12(18)14(13)15(11)19/h1-7,16-18H |
InChIKey: | TZBJGXHYKVUXJN-UHFFFAOYSA-N |
Canonical Smiles: | C1=CC(=CC=C1C2=COC3=CC(=CC(=C3C2=O)O)O)O |
Isomeric Smiles: | C1=CC(=CC=C1C2=COC3=CC(=CC(=C3C2=O)O)O)O |
Molecular Weight: | 270.24 |
Molecular Formula: | C15H10O5 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
genistein
Molecular Weight: | 270.24 |
Molecular Formula: | C15H10O5 |
Hydrogen Bond Donor Count: | 3 |
Hydrogen Bond Acceptor Count: | 5 |
Rotatable Bond Count: | 1 |
Heavy Atom Count: | 20 |
Complexity: | 411 |
Synonyms
genistein
| genistein | genistein |
|---|---|
genistein |
446-72-0 |
Prunetol |
Genisterin |
4,5,7-Trihydroxyisoflavone |
Genisteol |
Sophoricol |
5,7-dihydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one |
5,7,4-Trihydroxyisoflavone |
Bonistein |
Differenol A |
NPI 031L |
5,7-dihydroxy-3-(4-hydroxyphenyl)chromen-4-one |
5,7-Dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one |
4H-1-Benzopyran-4-one, 5,7-dihydroxy-3-(4-hydroxyphenyl)- |
C.I. 75610 |
SIPI 807-1 |
MFCD00016952 |
5,7-Dihydroxy-3-(4-hydroxyphenyl)-4-benzopyrone |
UNII-DH2M523P0H |
NSC 36586 |
NSC36586 |
CHEMBL44 |
Bio 300 |
ISOFLAVONE, 4,5,7-TRIHYDROXY- |
MLS000738127 |
DH2M523P0H |
Genestein |
CHEBI:28088 |
Genistein (USAN) |
Genistein USAN |
NSC-36586 |
GEN |
NCGC00015479-09 |
DSSTox_CID_2308 |
DSSTox_RID_76542 |
DSSTox_GSID_22308 |
CAS-446-72-0 |
Lactoferrin-genistein |
CCRIS 7675 |
4,5, 7-Trihydroxyisoflavone |
SR-01000075498 |
EINECS 207-174-9 |
BRN 0263823 |
STO514 |
HSDB 7475 |
PTI G4660 |
PTI-G4660 |
SIPI-9764-I |
3kgt |
3kgu |
Genistein, 8 |
Genistein,(S) |
PTI-G 4660 |
4′,5,7-Trihydroxyisoflavone |
TNP00151 |
Genistein (flavonoid) |
Spectrum_000320 |
Tocris-1110 |
1x7r |
2qa8 |
Genistein 85% HPLC |
SpecPlus_000305 |
Spectrum2_000638 |
Spectrum3_000678 |
Spectrum4_001543 |
Spectrum5_000106 |
Lopac-G-6649 |
4,7-Trihydroxyisoflavone |
MolMap_000022 |
UPCMLD-DP096 |
G 6649 |
4,5,7-Trihydroxyisoflavone |
Isoflavone,5,7-trihydroxy- |
Lopac0_000520 |
Oprea1_224620 |
Oprea1_437815 |
SCHEMBL19166 |
BSPBio_002375 |
KBioGR_002006 |
KBioGR_002564 |
KBioSS_000800 |
KBioSS_002573 |
SPECTRUM210296 |
5-18-04-00594 (Beilstein Handbook Reference) |
BIDD:ER0113 |
DivK1c_006401 |
Genistein, analytical standard |
SPBio_000636 |
4,5,7-trihydroxy-Isoflavone |
GTPL2826 |
MEGxp0_000568 |
NPI-031L |
4,5,7-Trihydroxy Iso-Flavone |
DTXSID5022308 |
UPCMLD-DP096:001 |
ACon1_001065 |
BDBM19459 |
cid_5280961 |
KBio1_001345 |
KBio2_000800 |
KBio2_002564 |
KBio2_003368 |
KBio2_005132 |
KBio2_005936 |
KBio2_007700 |
KBio3_001595 |
KBio3_003042 |
AOB5073 |
BIO-300 |
CHEBI: 28088 |
cMAP_000086 |
Bio1_000445 |
Bio1_000934 |
Bio1_001423 |
HMS2271K09 |
HMS3261H21 |
HMS3267K14 |
HMS3412I13 |
HMS3428M01 |
HMS3649B22 |
HMS3654D17 |
HMS3676I13 |
HMS3742I07 |
SIPI-807-1 |
ACT05962 |
ALBB-015886 |
AMY25676 |
BCP07581 |
Tox21_110161 |
Tox21_201428 |
Tox21_300585 |
Tox21_500520 |
AC-472 |
BBL010484 |
CCG-38551 |
FW-635I-2 |
LMPK12050218 |
s1342 |
SBB066115 |
STK801619 |
WHO 11073 |
ZINC18825330 |
AKOS001590147 |
Tox21_110161_1 |
CS-1534 |
DB01645 |
KS-5128 |
LP00520 |
MCULE-4857649752 |
SB17235 |
SDCCGSBI-0050503.P003 |
SMP1_000133 |
Genistein; 4,5,7-Trihydroxyisoflavone |
NCGC00015479-01 |
NCGC00015479-02 |
NCGC00015479-04 |
NCGC00015479-05 |
NCGC00015479-06 |
NCGC00015479-07 |
NCGC00015479-08 |
NCGC00015479-10 |
NCGC00015479-11 |
NCGC00015479-12 |
NCGC00015479-13 |
NCGC00015479-14 |
NCGC00015479-15 |
NCGC00015479-16 |
NCGC00015479-17 |
NCGC00015479-18 |
NCGC00015479-19 |
NCGC00015479-20 |
NCGC00015479-38 |
NCGC00025005-01 |
NCGC00025005-02 |
NCGC00025005-03 |
NCGC00025005-04 |
NCGC00025005-05 |
NCGC00025005-06 |
NCGC00025005-07 |
NCGC00169711-01 |
NCGC00169711-02 |
NCGC00254275-01 |
NCGC00258979-01 |
NCGC00261205-01 |
690224-00-1 |
HY-14596 |
NCI60_003369 |
SMR000112580 |
ST056352 |
SY050124 |
EU-0100520 |
FT-0603395 |
FT-0668961 |
FT-0668962 |
G0272 |
N1861 |
SW203763-2 |
46G720 |
C06563 |
D11680 |
G-2535 |
Genistein, synthetic, >=98% (HPLC), powder |
J10015 |
K00046 |
US8552057, 2 |
AB00052696_09 |
AB00052696_12 |
A826657 |
Q415957 |
Genistein, primary pharmaceutical reference standard |
Q-100484 |
SR-01000075498-1 |
SR-01000075498-3 |
SR-01000075498-6 |
3-(4-hydroxyphenyl)-5,7-bis(oxidanyl)chromen-4-one |
BRD-K43797669-001-02-3 |
BRD-K43797669-001-03-1 |
BRD-K43797669-001-10-6 |
Genistein, from Glycine max (soybean), ~98% (HPLC) |
SR-01000075498-10 |
5,7-dihydroxy-3-(4-hydroxyphenyl)-1-benzopyran-4-one |
F0001-2388 |
4H-1-Benzopyran-4-one,7-dihydroxy-3-(4-hydroxyphenyl)- |
UNII-71B37NR06D component TZBJGXHYKVUXJN-UHFFFAOYSA-N |
Genistein, United States Pharmacopeia (USP) Reference Standard |
Genistein, Pharmaceutical Secondary Standard; Certified Reference Material |
5,7-DIHYDROXY-3-(4-HYDROXYPHENYL)-4H-1-BENZOPYRAN-4-ONE; 4,5,7-TRIHYDROXYISOFLAVONE; PRUNETOL; GENISTEOL" |
Experimental Data
genistein
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 50 | umol/L | -5.35 | NS | N2 | 30970250 | Inactive | ||||||
| Caenorhabditis elegans | 2.5 | umol/L | 0 | NS | N2 | 32735859 | Inactive | ||||||
| Caenorhabditis elegans | 10 | umol/L | 0 | NS | N2 | 32735859 | Inactive | ||||||
| Caenorhabditis elegans | 5 | umol/L | 0 | S | N2 | 32735859 | Active | ||||||
| Caenorhabditis elegans | 20 | umol/L | 0 | NS | N2 | 32735859 | Inactive | ||||||
| Caenorhabditis elegans | 50 | umol/L | S | N2 | 33683565 | ||||||||
| Drosophila melanogaster | 20 | umol/L | 49.36 | 46.38 | -6.022 | NS | FEMALES | 33008901 | Inactive | ||||
| Caenorhabditis elegans | 50 | umol/L | 10 | S | N2 | 25593647 | Active | ||||||
| Caenorhabditis elegans | 100 | umol/L | 27.9 | 68.4 | S | N2 | 25593647 | Active | |||||
| Caenorhabditis elegans | 100 | umol/L | 28 | S | N2 | 31201898 | Active | ||||||
| Drosophila melanogaster | 200 | umol/L | 45.82 | 41.62 | -9.167 | NS | MALES | 33008901 | Inactive | ||||
| Drosophila melanogaster | 20 | umol/L | 46.24 | 50.41 | 9.029 | S | FEMALES | 33008901 | Active | ||||
| Caenorhabditis elegans | 50 | umol/L | 10 | S | N2 | 31201898 | Active | ||||||
| Caenorhabditis elegans | 33 | umol/L | 6 | NS | N2 | 24134630 | Inactive | ||||||
| Caenorhabditis elegans | 100 | umol/L | 15.86 | 15.74 | -0.7161 | NS | N2 | 33008901 | Inactive | ||||
| Drosophila melanogaster | 200 | umol/L | 46.64 | 46.9 | 0.5541 | NS | MALES | 33008901 | Inactive | ||||
| Caenorhabditis elegans | 100 | umol/L | 27.9 | S | N2 | 33683565 | Active |
Experimental Data Visualization
genistein
Statistics Data
genistein
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 28 | 68.4 | 7 | 13 |
| Drosophila melanogaster | 9.029 | 1 | 4 |
Statistics Data Visualization
genistein
