Compound Summary
Compound Information
luteolin
Compound Name: | luteolin |
Compound CID: | 5280445 |
Synonyms: | luteolin 491-70-3 Digitoflavone Luteolol 3,4,5,7-Tetrahydroxyflavone More... |
Iupac Name: | 2-(3,4-dihydroxyphenyl)-5,7-dihydroxychromen-4-one |
InChI: | InChI=1S/C15H10O6/c16-8-4-11(19)15-12(20)6-13(21-14(15)5-8)7-1-2-9(17)10(18)3-7/h1-6,16-19H |
InChIKey: | IQPNAANSBPBGFQ-UHFFFAOYSA-N |
Canonical Smiles: | C1=CC(=C(C=C1C2=CC(=O)C3=C(C=C(C=C3O2)O)O)O)O |
Isomeric Smiles: | C1=CC(=C(C=C1C2=CC(=O)C3=C(C=C(C=C3O2)O)O)O)O |
Molecular Weight: | 286.24 |
Molecular Formula: | C15H10O6 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
luteolin
Molecular Weight: | 286.24 |
Molecular Formula: | C15H10O6 |
Hydrogen Bond Donor Count: | 4 |
Hydrogen Bond Acceptor Count: | 6 |
Rotatable Bond Count: | 1 |
Heavy Atom Count: | 21 |
Complexity: | 447 |
Synonyms
luteolin
| luteolin | luteolin |
|---|---|
luteolin |
491-70-3 |
Digitoflavone |
Luteolol |
3,4,5,7-Tetrahydroxyflavone |
2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one |
Flacitran |
Luteoline |
Salifazide |
Weld Lake |
Cyanidenon 1470 |
5,7,3,4-Tetrahydroxyflavone |
C.I. Natural Yellow 2 |
Daphneflavonol |
Flavopurpol |
2-(3,4-dihydroxyphenyl)-5,7-dihydroxychromen-4-one |
Bismite |
4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy- |
2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-4-benzopyrone |
UNII-KUX1ZNC9J2 |
BRN 0292084 |
MFCD00017309 |
KUX1ZNC9J2 |
CHEMBL151 |
FLAVONE, 3,4,5,7-TETRAHYDROXY- |
CHEBI:15864 |
2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-1-benzopyran-4-one |
2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-4-chromenone |
2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-chromen-4-one |
Yama kariyasu |
1318-21-4 |
SMR000326896 |
7-Tetrahydroxyflavone |
CCRIS 3790 |
SR-01000779333 |
EINECS 207-741-0 |
Argemexitin |
C.I. 75590 |
4dew |
4dgn |
4hkn |
Luteolin,(S) |
LU2 |
Prestwick_122 |
3′,4′,5,7-Tetrahydroxyflavone |
Prestwick0_000870 |
Prestwick1_000870 |
Prestwick2_000870 |
Prestwick3_000870 |
ACMC-209kf3 |
BIDD:PXR0059 |
Lopac0_000660 |
Oprea1_849964 |
SCHEMBL20426 |
BSPBio_000919 |
Luteolin, analytical standard |
MLS000697655 |
MLS000860038 |
MLS002154043 |
MLS006011917 |
BIDD:ER0122 |
SPBio_002840 |
BDBM7459 |
BPBio1_001011 |
GTPL5215 |
MEGxp0_000143 |
DTXSID4074988 |
ACon1_000223 |
cid_5280445 |
AOB5669 |
HMS1570N21 |
HMS2097N21 |
HMS2220C06 |
HMS3356L02 |
HMS3561N09 |
HMS3649N21 |
HMS3656A05 |
HMS3714N21 |
Luteolin, >=99.0% (TLC) |
BCP03511 |
HY-N0162 |
TNP00073 |
Luteolin, >=98% (TLC), powder |
BBL027837 |
CL0029 |
LMPK12110006 |
s2320 |
SBB066117 |
STK801923 |
ZINC18185774 |
AKOS002140588 |
AC-1125 |
BCP9000865 |
CCG-208309 |
CS-4611 |
DB15584 |
KS-5202 |
MCULE-6874646775 |
Luteolin 100 microg/mL in Acetonitrile |
SMP2_000042 |
NCGC00016467-01 |
NCGC00016467-02 |
NCGC00016467-03 |
NCGC00016467-04 |
NCGC00016467-05 |
NCGC00016467-06 |
NCGC00016467-07 |
NCGC00016467-08 |
NCGC00142375-01 |
NCGC00142375-02 |
NCGC00142375-03 |
NCGC00179375-01 |
NCGC00179375-02 |
CAS-491-70-3 |
ST024703 |
SY030155 |
BCP0726000198 |
AB0010480 |
FT-0600053 |
N1831 |
SW196433-3 |
T2682 |
91L703 |
C01514 |
J10229 |
L 9283 |
S00110 |
A827664 |
Luteolin, primary pharmaceutical reference standard |
Q415011 |
Q-100551 |
SR-01000779333-4 |
SR-01000779333-5 |
SR-01000779333-7 |
BRD-K05236810-001-05-9 |
23A002A4-B47B-46CD-848C-65042EACF3FF |
NCGC00142375-01,NCGC00142375-02 |
2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-4H-benzopyrone-4-one |
2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one # |
4H-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy- |
4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy- (9CI) |
Experimental Data
luteolin
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 50 | umol/L | 5.89 | NS | N2 | 30970250 | Inactive | ||||||
| Caenorhabditis elegans | 100 | umol/L | 0 | S | N2 | 32334190 | Active | ||||||
| Caenorhabditis elegans | 5 | umol/L | 32 | 32 | 0 | 50 | 56 | 0.12 | NS | N2 | 29375370 | Inactive | |
| Caenorhabditis elegans | 100 | umol/L | 32 | 34 | 0.06 | 50 | 56 | 0.12 | S | N2 | 29375370 | Active | |
| Caenorhabditis elegans | 10 | umol/L | 32 | 27 | -0.16 | 50 | 52 | 0.04 | NS | N2 | 29375370 | Inactive | |
| Drosophila melanogaster | 0.5 | umol/L | 50 | 40 | -0.2 | 59 | 59 | 0 | NS | w1118 | MALES | 29375370 | Inactive |
| Drosophila melanogaster | 0.5 | umol/L | 58 | 61 | 0.05 | 85 | 81 | -0.05 | S | w1118 | FEMALES | 29375370 | Active |
| Drosophila melanogaster | 0.3 | umol/L | 58 | 61 | 0.05 | 85 | 83 | -0.02 | S | w1118 | FEMALES | 29375370 | Active |
| Caenorhabditis elegans | 0.5 | umol/L | 32 | 27 | -0.16 | 50 | 54 | 0.08 | S | N2 | 29375370 | Inactive | |
| Caenorhabditis elegans | 1 | umol/L | 32 | 28 | -0.12 | 50 | 54 | 0.08 | NS | N2 | 29375370 | Inactive | |
| Drosophila melanogaster | 1 | umol/L | 58 | 61 | 0.05 | 85 | 81 | -0.05 | S | w1118 | FEMALES | 29375370 | Active |
| Drosophila melanogaster | 0.3 | umol/L | 50 | 44 | -0.12 | 59 | 57 | -0.03 | S | w1118 | MALES | 29375370 | Inactive |
| Drosophila melanogaster | 1 | umol/L | 50 | 40 | -0.2 | 59 | 59 | 0 | S | w1118 | MALES | 29375370 | Inactive |
Experimental Data Visualization
luteolin
Statistics Data
luteolin
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 5.89 | 0.12 | 3 | 7 |
| Drosophila melanogaster | 0.05 | 0 | 1 | 6 |
Statistics Data Visualization
luteolin
