Compound Summary
Compound Information
APRACLONIDINE HYDROCHLORIDE
Compound Name: | APRACLONIDINE HYDROCHLORIDE |
Compound CID: | 51763 |
Synonyms: | APRACLONIDINE HYDROCHLORIDE 73218-79-8 Apraclonidine HCl p-Aminoclonidine hydrochloride 2,6-dichloro-N1-(4,5-dihydro-1H-imidazol-2-yl)benzene-1,4-diamine hydrochloride More... |
Iupac Name: | 2,6-dichloro-1-N-(4,5-dihydro-1H-imidazol-2-yl)benzene-1,4-diamine;hydrochloride |
InChI: | InChI=1S/C9H10Cl2N4.ClH/c10-6-3-5(12)4-7(11)8(6)15-9-13-1-2-14-9;/h3-4H,1-2,12H2,(H2,13,14,15);1H |
InChIKey: | OTQYGBJVDRBCHC-UHFFFAOYSA-N |
Canonical Smiles: | C1CN=C(N1)NC2=C(C=C(C=C2Cl)N)Cl.Cl |
Isomeric Smiles: | C1CN=C(N1)NC2=C(C=C(C=C2Cl)N)Cl.Cl |
Molecular Weight: | 281.6 |
Molecular Formula: | C9H11Cl3N4 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
APRACLONIDINE HYDROCHLORIDE
Molecular Weight: | 281.6 |
Molecular Formula: | C9H11Cl3N4 |
Hydrogen Bond Donor Count: | 4 |
Hydrogen Bond Acceptor Count: | 2 |
Rotatable Bond Count: | 2 |
Heavy Atom Count: | 16 |
Complexity: | 247 |
Synonyms
APRACLONIDINE HYDROCHLORIDE
| APRACLONIDINE HYDROCHLORIDE | APRACLONIDINE HYDROCHLORIDE |
|---|---|
APRACLONIDINE HYDROCHLORIDE |
73218-79-8 |
Apraclonidine HCl |
p-Aminoclonidine hydrochloride |
2,6-dichloro-N1-(4,5-dihydro-1H-imidazol-2-yl)benzene-1,4-diamine hydrochloride |
Iopidine |
ALO-2145 |
UNII-D2VW67N38H |
Apraclonidine (hydrochloride) |
Aplonidine hydrochloride |
2-(4-Amino-2,6-dichlorophenylimino)imidazolidine hydrochloride |
3,5-Dichloro-4-(2-imidazolidinylidenimino)aniline hydrochloride |
Apraclonidine hydrochloride |
2-((4-Amino-2,6-dichlorophenyl)imino)imidazolidine monohydrochloride |
AL 02145 |
CHEBI:2789 |
D2VW67N38H |
73218-79-8 (Apraclonidine HCl) |
AL02145 |
NCGC00093552-01 |
Iopidine (TN) |
2,6-dichloro-1-N-(4,5-dihydro-1H-imidazol-2-yl)benzene-1,4-diamine;hydrochloride |
NC 14 hydrochloride |
2,6-Dichloro-N(1)-(2-imidazolidinylidene)-1,4-benzenediamine hydrochloride |
Iopidine ophthalmic solution |
2,6-Dichloro-N(1)-(4,5-dihydro-1H-imidazol-2-yl)-1,4-benzenediamine monohydrochloride |
ALO 2145; Aplonidine hydrochloride; Apraclonidine hydrochloride; Iopidine; p-Aminoclonidine monohydrochloride |
SMR000058965 |
AL-02145 |
Apraclonidine hydrochloride USAN:USP |
2,6-Dichloro-N(sup 1)-(2-imidazolidinylidene)-1,4-benzenediamine hydrochloride |
2,6-Dichloro-N(sup 1)-(4,5-dihydro-1H-imidazol-2-yl)-1,4-benzenediamine monohydrochloride |
DSSTox_CID_25749 |
DSSTox_RID_81093 |
DSSTox_GSID_45749 |
SCHEMBL41138 |
C9H11Cl3N4 |
MLS000028829 |
MLS006010230 |
CHEMBL1200379 |
DTXSID6045749 |
Tox21_111207 |
Tox21_500033 |
HY-12720A |
MFCD00135922 |
p-Aminoclonidine hydrochloride, solid |
s6583 |
AKOS022175501 |
AKOS025401362 |
Apraclonidine hydrochloride (JAN/USP) |
CCG-221337 |
DS-7631 |
LP00033 |
1,4-Benzenediamine, 2,6-dichloro-N(sup 1)-2-imidazolidinylidene-, monohydrochloride |
2-yl)benzene-1,4-diamine hydrochloride |
NCGC00260718-01 |
1,4-Benzenediamine, 2,6-dichloro-N(sup 1)-(4,5-dihydro-1H-imidazol-2-yl)-, monohydrochloride |
AC-12705 |
BA164186 |
S311 |
CAS-73218-79-8 |
DB-055734 |
CS-0031120 |
EU-0100033 |
FT-0602878 |
2,6-dichloro-N1-(4,5-dihydro-1H-imidazol- |
A 0779 |
C76333 |
D01008 |
218A798 |
A837749 |
A937077 |
SR-01000075247 |
SR-01000075247-1 |
Q27105817 |
2-(4-Amino-2,6-dichlorophenylimino)imidazolidinehydrochloride |
2-(2,6-dichloro-4-aminophenyl)iminoimidazolidine hydrochloride |
Apraclonidine hydrochloride 100 microg/mL in Acetonitrile:Methanol |
2,6-bis(chloranyl)-N1-(4,5-dihydro-1H-imidazol-2-yl)benzene-1,4-diamine hydrochloride |
Experimental Data
APRACLONIDINE HYDROCHLORIDE
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33 | umol/L | -6 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
APRACLONIDINE HYDROCHLORIDE
Statistics Data
APRACLONIDINE HYDROCHLORIDE
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | -6 | 1 | 1 |
Statistics Data Visualization
APRACLONIDINE HYDROCHLORIDE
