Compound Summary
Compound Information
rolipram
Compound Name: | rolipram |
Compound CID: | 5092 |
Synonyms: | rolipram 61413-54-5 ZK 62711 (R,S)-rolipram Rolipramum Latin More... |
Iupac Name: | 4-(3-cyclopentyloxy-4-methoxyphenyl)pyrrolidin-2-one |
InChI: | InChI=1S/C16H21NO3/c1-19-14-7-6-11(12-9-16(18)17-10-12)8-15(14)20-13-4-2-3-5-13/h6-8,12-13H,2-5,9-10H2,1H3,(H,17,18) |
InChIKey: | HJORMJIFDVBMOB-UHFFFAOYSA-N |
Canonical Smiles: | COC1=C(C=C(C=C1)C2CC(=O)NC2)OC3CCCC3 |
Isomeric Smiles: | COC1=C(C=C(C=C1)C2CC(=O)NC2)OC3CCCC3 |
Molecular Weight: | 275.34 |
Molecular Formula: | C16H21NO3 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
rolipram
Molecular Weight: | 275.34 |
Molecular Formula: | C16H21NO3 |
Hydrogen Bond Donor Count: | 1 |
Hydrogen Bond Acceptor Count: | 3 |
Rotatable Bond Count: | 4 |
Heavy Atom Count: | 20 |
Complexity: | 341 |
Synonyms
rolipram
| rolipram | rolipram |
|---|---|
rolipram |
61413-54-5 |
ZK 62711 |
(R,S)-rolipram |
Rolipramum Latin |
4-(3-(cyclopentyloxy)-4-methoxyphenyl)pyrrolidin-2-one |
Rolipramum |
4-3-(Cyclopentyloxy)-4-methoxyphenyl-2-pyrrolidinone |
4-3-(cyclopentyloxy)-4-methoxyphenylpyrrolidin-2-one |
Adeo |
(+/-)-Rolipram |
4-(3-cyclopentyloxy-4-methoxyphenyl)pyrrolidin-2-one |
4-(3-(Cyclopentyloxy)-4-methoxyphenyl)-2-pyrrolidinone |
ZK-62711 |
CHEMBL63 |
4-(3-Cyclopentyloxy-4-methoxyphenyl)-2-pyrrolidone |
SB 95952 |
C16H21NO3 |
MLS000069691 |
2-Pyrrolidinone, 4-3-(cyclopentyloxy)-4-methoxyphenyl- |
CHEBI:104872 |
MFCD00270906 |
SMR000058510 |
(4S)-4-3-(Cyclopentyloxy)-4-methoxyphenyl-pyrrolidin-2-one |
ZK 62 711 |
(R,S)-Rolipram;SB 95952;ZK 62711 |
DSSTox_CID_24124 |
DSSTox_RID_80104 |
DSSTox_GSID_44124 |
4-(3-Cyclopentyloxy-4-methoxy-phenyl)-pyrrolidin-2-one |
2-Pyrrolidinone, 4-(3-(cyclopentyloxy)-4-methoxyphenyl)- |
(4R)-4-3-(Cyclopentyloxy)-4 Methoxyphenyl)pyrrolidin-2-one |
Rolipram USAN:INN |
3Hrolipram |
3H-rolipram |
SR-01000000162 |
EINECS 262-771-1 |
4-(3-(cyclopentyloxy)-4-methoxyphenyl)-2-pyrrolidinon |
BRN 1588548 |
(plusmn)-rolipram |
NCGC00016899-01 |
CAS-61413-54-5 |
ME-3167 |
Opera_ID_1749 |
Prestwick0_000924 |
Prestwick1_000924 |
Prestwick2_000924 |
Prestwick3_000924 |
UPCMLD-DP110 |
Lopac0_001072 |
SCHEMBL27930 |
BSPBio_000828 |
BSPBio_001356 |
KBioGR_000076 |
KBioSS_000076 |
Rolipram (JAN/USAN/INN) |
MLS000758273 |
MLS000759531 |
MLS001146912 |
MLS001424084 |
MLS006010272 |
SPBio_003007 |
(+)-Rolipram; (S)-Rolipram |
BPBio1_000912 |
GTPL5260 |
GTPL5313 |
4-3-(cyclopentoxy)-4-methoxy-phenylpyrrolidin-2-one |
DTXSID3044124 |
UPCMLD-DP110:001 |
UPCMLD-DP110:002 |
BDBM14361 |
KBio2_000076 |
KBio2_002644 |
KBio2_005212 |
KBio3_000151 |
KBio3_000152 |
AOB5326 |
Bio2_000076 |
Bio2_000556 |
HMS1361D18 |
HMS1570J10 |
HMS1791D18 |
HMS1989D18 |
HMS2051N15 |
HMS2090J16 |
HMS2097J10 |
HMS2232F06 |
HMS3263G06 |
HMS3267A05 |
HMS3369J08 |
HMS3393N15 |
HMS3402D18 |
HMS3411F08 |
HMS3654P06 |
HMS3655J21 |
HMS3675F08 |
HMS3714J10 |
Pharmakon1600-01505683 |
BCP21910 |
BCP23388 |
Tox21_110672 |
Tox21_501072 |
2028AH |
2691AH |
NSC760125 |
Rolipram, solid, >=98% (HPLC) |
s1430 |
Rolipram - CAS 61413-54-5 |
AKOS015959793 |
Tox21_110672_1 |
CCG-100965 |
CCG-205149 |
CS-1754 |
DB01954 |
KS-1400 |
LP01072 |
NC00215 |
NSC 760125 |
NSC-760125 |
SB12922 |
SDCCGSBI-0051042.P003 |
IDI1_033826 |
NCGC00015898-03 |
NCGC00015898-04 |
NCGC00015898-05 |
NCGC00015898-06 |
NCGC00015898-07 |
NCGC00015898-08 |
NCGC00015898-09 |
NCGC00015898-11 |
NCGC00015898-12 |
NCGC00015898-15 |
NCGC00015898-31 |
NCGC00089796-02 |
NCGC00089796-04 |
NCGC00089796-05 |
NCGC00089796-06 |
NCGC00089796-07 |
NCGC00089796-08 |
NCGC00261757-01 |
AC-32927 |
HY-16900 |
SB-95952 |
ZK-62771 |
SBI-0051042.P002 |
AB0109850 |
DB-080675 |
AB00513966 |
EU-0101072 |
FT-0738515 |
R0110 |
ST50405218 |
SW196583-4 |
D01783 |
R 6520 |
AB00384360-17 |
AB00384360_19 |
A847969 |
Q410285 |
4-3-(cyclopentyloxy)-4-methoxyphenylpyrrolidinone |
SR-01000000162-3 |
SR-01000000162-4 |
SR-01000000162-5 |
SR-01000000162-9 |
4-3-Cyclopentyloxy-4-methoxyphenyl-2-pyrrolidinone |
BRD-A34255068-001-04-8 |
BRD-A34255068-001-26-1 |
SR-01000000162-12 |
4-(3-cyclopentyloxy-4-methoxy-phenyl)pyrrolidin-2-one |
4-(3-cyclopentyloxy-4-methoxyphenyl)-pyrrolidin-2-one |
4-4-Methoxy-3-(cyclopentyloxy)phenyl-2-pyrrolidinone |
2-Pyrrolidinone, 4-3-(cyclopentyloxy)-4-methoxyphenyl- (9CI) |
Experimental Data
rolipram
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33 | umol/L | -6 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
rolipram
Statistics Data
rolipram
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | -6 | 1 | 1 |
Statistics Data Visualization
rolipram
