Compound Summary
Compound Information
promethazine
Compound Name: | promethazine |
Compound CID: | 4927 |
Synonyms: | promethazine Proazamine 60-87-7 Diphergan Promethazin More... |
Iupac Name: | N,N-dimethyl-1-phenothiazin-10-ylpropan-2-amine |
InChI: | InChI=1S/C17H20N2S/c1-13(18(2)3)12-19-14-8-4-6-10-16(14)20-17-11-7-5-9-15(17)19/h4-11,13H,12H2,1-3H3 |
InChIKey: | PWWVAXIEGOYWEE-UHFFFAOYSA-N |
Canonical Smiles: | CC(CN1C2=CC=CC=C2SC3=CC=CC=C31)N(C)C |
Isomeric Smiles: | CC(CN1C2=CC=CC=C2SC3=CC=CC=C31)N(C)C |
Molecular Weight: | 284.4 |
Molecular Formula: | C17H20N2S |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
promethazine
Molecular Weight: | 284.4 |
Molecular Formula: | C17H20N2S |
Hydrogen Bond Donor Count: | 0 |
Hydrogen Bond Acceptor Count: | 3 |
Rotatable Bond Count: | 3 |
Heavy Atom Count: | 20 |
Complexity: | 298 |
Synonyms
promethazine
| promethazine | promethazine |
|---|---|
promethazine |
Proazamine |
60-87-7 |
Diphergan |
Promethazin |
Phenargan |
Phensedyl |
Promazinamide |
Promezathine |
Protazine |
Isophenergan |
Diprazine |
Diprozin |
Fenetazina |
Histargan |
Prometazin |
Prothazin |
Provigan |
Thiergan |
Vallergine |
Avomine |
Dimapp |
Fargan |
Fenazil |
Hiberna |
Phargan |
Procit |
Prorex |
Tanidil |
Promethacon |
Promethegan |
Pyrethiazine |
Lilly 1516 |
Prometazina |
Atosil |
Promethazinum |
Promethiazine |
Iergigan |
Lercigan |
Pilpophen |
Proazaimine |
Prometasin |
Pyrethia |
Lilly 01516 |
SKF 1498 |
(2-Dimethylamino-2-methyl)ethyl-N-dibenzoparathiazine |
WY 509 |
10-2-(Dimethylamino)propylphenothiazine |
N-(2-Dimethylamino-2-methyl)ethylphenothiazine |
RP 3277 |
Lergigan |
Dimethylamino-isopropyl-phenthiazin |
N,N,alpha-Trimethyl-10H-phenothiazine-10-ethanamine |
N-Dimethylamino-2-methylethyl thiodiphenylamine |
10-(2-Dimethylaminopropyl)phenothiazine |
A-91033 |
NCI-C60673 |
10-(2-(Dimethylamino)-2-methylethyl)phenothiazine |
Zipan-25 |
10H-Phenothiazine-10-ethanamine, N,N,alpha-trimethyl- |
3277 RP |
(+/-)-promethazine |
10-(2-(Dimethylamino)propyl)phenothiazine |
Phenothiazine, 10-(2-dimethylaminopropyl)- |
N,N-dimethyl-1-(10H-phenothiazin-10-yl)propan-2-amine |
CHEMBL643 |
60-87-7 (free base) |
10H-Phenothiazine-10-ethanamine, N,N,.alpha.-trimethyl- |
CHEBI:8461 |
Antiallersin |
Fenetazine |
Phenerzine |
Pipolphene |
Camergan |
Metaryl |
Pelpica |
Pilothia |
Promacot |
Promergan |
Promesan |
Prometh |
PromethazineHcl |
Phenothiazine, 10-2-(dimethylamino)propyl- |
NSC-30321 |
Phenoject-50 |
NCGC00015817-05 |
Prometazine |
Prothazine |
Valergine |
DSSTox_CID_3518 |
DSSTox_RID_77061 |
DSSTox_GSID_23518 |
Pro-50 |
Promethazine INN:BAN |
Prometazina INN-Spanish |
Promethazinum INN-Latin |
dimethyl1-(10H-phenothiazin-10-yl)propan-2-ylamine |
ZIPAN-50 |
UNII-FF28EJQ494 |
CAS-60-87-7 |
CCRIS 7056 |
HSDB 3173 |
Dimethylamino-isopropyl-phenthiazin German |
EINECS 200-489-2 |
Promethazine (JAN/INN) |
NSC 30321 |
BRN 0088554 |
Sominex |
Phenergan base |
SR-01000002993 |
FF28EJQ494 |
N,N-dimethyl-1-phenothiazin-10-ylpropan-2-amine |
Remsed (Salt/Mix) |
3389 R.p. |
Pyrethia (Salt/Mix) |
Pipolphen (Salt/Mix) |
Spectrum_000868 |
Prestwick0_000888 |
Prestwick1_000888 |
Prestwick2_000888 |
Prestwick3_000888 |
Spectrum2_000840 |
Spectrum3_001019 |
Spectrum4_001149 |
Spectrum5_000977 |
(.+/-.)-Promethazine |
10H-Phenothiazine-10-ethanamine, N,N,alpha-trimethyl-, radical ion(1+) |
SCHEMBL4700 |
Lopac0_000899 |
Oprea1_758749 |
BSPBio_000676 |
BSPBio_002777 |
KBioGR_001697 |
KBioSS_001348 |
38878-40-9 |
4-27-00-01253 (Beilstein Handbook Reference) |
DivK1c_000005 |
SPBio_000799 |
SPBio_002895 |
(Dimethylamino-2-propyl-10-phenothiazine hydrochloride |
BPBio1_000744 |
GTPL7282 |
DTXSID7023518 |
KBio1_000005 |
KBio2_001348 |
KBio2_003916 |
KBio2_006484 |
KBio3_001997 |
PWWVAXIEGOYWEE-UHFFFAOYSA- |
EX-A891 |
N,N-Dimethyl-1-(10H-phenothiazin-10-yl)-2-propanamine |
N,N-DIMETHYL-1-PHENOTHIAZIN-10-YL-PROPAN-2-AMINE |
NINDS_000005 |
HMS2089E08 |
N,N-dimethyl-1-phenothiazin-10-ylpropan-2-amine hydrochloride |
NSC30321 |
Tox21_110227 |
BDBM50017696 |
MFCD00066294 |
AKOS015962127 |
Tox21_110227_1 |
4182 R.p. |
CCG-109848 |
DB01069 |
MCULE-8146430046 |
RP-3277 |
SDCCGSBI-0050874.P005 |
IDI1_000005 |
NCGC00015817-03 |
NCGC00015817-04 |
NCGC00015817-06 |
NCGC00015817-08 |
NCGC00015817-09 |
NCGC00015817-10 |
NCGC00015817-11 |
NCGC00015817-12 |
NCGC00015817-14 |
NCGC00015817-17 |
NCGC00015817-24 |
NCGC00089735-02 |
NCGC00089735-03 |
AC-15939 |
NCI60_001878 |
SBI-0050874.P004 |
AB00053535 |
FT-0700342 |
S5196 |
WLN: T C666 BN ISJ B1Y1&N1&1 |
C07404 |
D00494 |
F17386 |
AB00053535-12 |
AB00053535_13 |
10H-Phenothiazine-10-ethanamine,N,N,b-trimethyl- |
L000495 |
Q422970 |
J-690333 |
10H-Phenothiazine-10-ethanamine,N,.alpha.-trimethyl- |
SR-01000002993-10 |
N,N-Dimethyl-1-(10H-phenothiazin-10-yl)-2-propanamine # |
10H-Phenothiazine-10-ethanamine, N,N,alpha-trimethyl- (9CI) |
Experimental Data
promethazine
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Drosophila melanogaster | 20 | umol/L | 48.86 | 48.06 | -1.627 | NS | FEMALES | 33008901 | Inactive | ||||
| Drosophila melanogaster | 200 | umol/L | 44.01 | 48.4 | 9.979 | NS | MALES | 33008901 | Inactive |
Experimental Data Visualization
promethazine
Statistics Data
promethazine
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Drosophila melanogaster | 9.979 | 1 | 2 |
Statistics Data Visualization
promethazine
