Compound Summary
Compound Information
primidone
Compound Name: | primidone |
Compound CID: | 4909 |
Synonyms: | primidone 125-33-7 Primaclone Mysoline 2-Deoxyphenobarbital More... |
Iupac Name: | 5-ethyl-5-phenyl-1,3-diazinane-4,6-dione |
InChI: | InChI=1S/C12H14N2O2/c1-2-12(9-6-4-3-5-7-9)10(15)13-8-14-11(12)16/h3-7H,2,8H2,1H3,(H,13,15)(H,14,16) |
InChIKey: | DQMZLTXERSFNPB-UHFFFAOYSA-N |
Canonical Smiles: | CCC1(C(=O)NCNC1=O)C2=CC=CC=C2 |
Isomeric Smiles: | CCC1(C(=O)NCNC1=O)C2=CC=CC=C2 |
Molecular Weight: | 218.25 |
Molecular Formula: | C12H14N2O2 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
primidone
Molecular Weight: | 218.25 |
Molecular Formula: | C12H14N2O2 |
Hydrogen Bond Donor Count: | 2 |
Hydrogen Bond Acceptor Count: | 2 |
Rotatable Bond Count: | 2 |
Heavy Atom Count: | 16 |
Complexity: | 279 |
Synonyms
primidone
| primidone | primidone |
|---|---|
primidone |
125-33-7 |
Primaclone |
Mysoline |
2-Deoxyphenobarbital |
Lepimidin |
Liskantin |
Mylepsinum |
Lepsiral |
Misodine |
Mizodin |
Mylepsin |
Neurosyn |
Primidon |
Sertan |
2-Desoxyphenobarbital |
Hexadiona |
Majsolin |
Milepsin |
Misolyne |
Prilepsin |
Primakton |
Primoline |
Prysoline |
Midone |
Mizolin |
Mysedon |
Cyral |
Medi-Pets |
Primacone |
Desoxyphenobarbitone |
Pyrimidone Medi-pets |
5-ethyl-5-phenyl-1,3-diazinane-4,6-dione |
Primidona |
Primidonum |
Roe 101 |
5-Phenyl-5-ethyl-hexahydropyrimidine-4,6-dione |
4,6(1H,5H)-Pyrimidinedione, 5-ethyldihydro-5-phenyl- |
5-ethyl-5-phenyldihydropyrimidine-4,6(1H,5H)-dione |
NCI-C56360 |
Primidone (primaclone) |
5-Ethyl-5-phenylhexahydropyrimidine-4,6-dione |
5-Ethyldihydro-5-phenyl-4,6(1H,5H)-pyrimidinedione |
5-Ethylhexahydro-4,6-dioxo-5-phenylpyrimidine |
5-Ethylhexahydro-5-phenylpyrimidine-4,6-dione |
NSC 41701 |
5-Aethyl-5-phenyl-hexahydropyrimidin-4,6-dion |
UNII-13AFD7670Q |
CHEBI:8412 |
Resimatil |
5-Phenyl-5-aethylhexahydropyrimidindion-(4,6) |
MLS000028593 |
Primacione |
13AFD7670Q |
NSC-41701 |
NCGC00015834-11 |
CAS-125-33-7 |
SMR000058501 |
DSSTox_CID_3510 |
Primidonum INN-Latin |
DSSTox_RID_77058 |
DSSTox_GSID_23510 |
Primidona INN-Spanish |
5-ethyldihydro-5-phenyl-4,61H,5H-pyrimidinedione |
Hexamidine (the antispasmodic) |
CCRIS 54 |
Mysoline (TN) |
HSDB 3169 |
SR-01000003162 |
EINECS 204-737-0 |
BRN 0218034 |
5-ethyl-5-phenyl-1,2,3,5-tetrahydropyrimidine-4,6-dione |
Hexamidine(the antispasmodic) |
5-Aethyl-5-phenyl-hexahydropyrimidin-4,6-dion German |
5-Phenyl-5-aethylhexahydropyrimidindion-(4,6) German |
Primidone USP:INN:BAN:JAN |
Primidone solution |
Primidone(Mysoline) |
Sodiumtrimetaphosphate |
Primidone (Mysoline) |
Spectrum_000832 |
Tocris-0830 |
Pyrimidone Medi-pets |
Opera_ID_1083 |
Prestwick0_000933 |
Prestwick1_000933 |
Prestwick2_000933 |
Prestwick3_000933 |
Spectrum2_001293 |
Spectrum3_000553 |
Spectrum4_000485 |
Spectrum5_001144 |
Lopac-P-7295 |
Biomol-NT_000261 |
CHEMBL856 |
P 7295 |
Pyrimidone Medi-pets |
Lopac0_001021 |
SCHEMBL34221 |
BSPBio_000866 |
BSPBio_002225 |
KBioGR_000969 |
KBioSS_001312 |
5-24-08-00102 (Beilstein Handbook Reference) |
MLS001055411 |
MLS001074125 |
BIDD:GT0319 |
DivK1c_000324 |
Primidone, analytical standard |
SPECTRUM1500501 |
SPBio_001325 |
SPBio_003035 |
Primidone (JP17/USP/INN) |
BPBio1_000859 |
BPBio1_000954 |
GTPL5338 |
ZINC1979 |
DTXSID7023510 |
HMS501A06 |
KBio1_000324 |
KBio2_001312 |
KBio2_003880 |
KBio2_006448 |
KBio3_001725 |
WLN: T6MV DVMTJ C2 CR |
NINDS_000324 |
HMS1570L08 |
HMS1920J20 |
HMS2092A21 |
HMS2097L08 |
HMS2236G03 |
HMS3259K04 |
HMS3263M03 |
HMS3266H18 |
HMS3369J12 |
HMS3411N13 |
HMS3655L05 |
HMS3675N13 |
HMS3714L08 |
HMS3884A18 |
Pharmakon1600-01500501 |
HY-B0339 |
NSC41701 |
Tox21_110238 |
Tox21_201948 |
Tox21_303194 |
Tox21_501021 |
BDBM50248152 |
CCG-39231 |
MFCD00038662 |
NSC757291 |
s1965 |
SBB017254 |
AKOS003368409 |
Tox21_110238_1 |
DB00794 |
KS-5217 |
LP01021 |
MCULE-2519004832 |
NC00532 |
NSC-757291 |
SDCCGSBI-0050994.P005 |
IDI1_000324 |
SMP1_000135 |
NCGC00015834-01 |
NCGC00015834-02 |
NCGC00015834-03 |
NCGC00015834-04 |
NCGC00015834-05 |
NCGC00015834-06 |
NCGC00015834-07 |
NCGC00015834-08 |
NCGC00015834-09 |
NCGC00015834-10 |
NCGC00015834-12 |
NCGC00015834-13 |
NCGC00015834-14 |
NCGC00015834-15 |
NCGC00015834-16 |
NCGC00015834-17 |
NCGC00015834-19 |
NCGC00015834-28 |
NCGC00016377-01 |
NCGC00023254-02 |
NCGC00023254-04 |
NCGC00023254-05 |
NCGC00023254-06 |
NCGC00023254-07 |
NCGC00023254-08 |
NCGC00023254-09 |
NCGC00023254-10 |
NCGC00257146-01 |
NCGC00259497-01 |
NCGC00261706-01 |
BP166193 |
H808 |
ST076725 |
SBI-0050994.P004 |
AB0013274 |
AB00052079 |
EU-0101021 |
FT-0603328 |
FT-0674032 |
P1906 |
SW196576-3 |
5-Ethyldihydro-5-phenyl-4,5H)-pyrimidinedione |
C07371 |
C71997 |
D00474 |
AB00052079-14 |
AB00052079_15 |
AB00052079_16 |
125P337 |
4,5H)-Pyrimidinedione, 5-ethyldihydro-5-phenyl- |
A805374 |
Q420383 |
J-005215 |
SR-01000003162-2 |
SR-01000003162-4 |
SR-01000003162-5 |
SR-01000003162-8 |
BRD-K32247306-001-05-4 |
BRD-K32247306-001-17-9 |
5-Ethyl-5-phenyldihydro-4,6(1H,5H)-pyrimidinedione # |
Primidone, European Pharmacopoeia (EP) Reference Standard |
Primidone, United States Pharmacopeia (USP) Reference Standard |
5-Ethyl-5-phenylhexahydropyrimidine-4,6-dione / 2-Deoxyphenobarbital |
Primidone for peak identification, European Pharmacopoeia (EP) Reference Standard |
Primidone solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material |
Experimental Data
primidone
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33 | umol/L | 7 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
primidone
Statistics Data
primidone
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 7 | 1 | 1 |
Statistics Data Visualization
primidone
