Compound Summary
Compound Information
praziquantel
Compound Name: | praziquantel |
Compound CID: | 4891 |
Synonyms: | praziquantel 55268-74-1 Biltricide Droncit Pyquiton More... |
Iupac Name: | 2-(cyclohexanecarbonyl)-3,6,7,11b-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4-one |
InChI: | InChI=1S/C19H24N2O2/c22-18-13-20(19(23)15-7-2-1-3-8-15)12-17-16-9-5-4-6-14(16)10-11-21(17)18/h4-6,9,15,17H,1-3,7-8,10-13H2 |
InChIKey: | FSVJFNAIGNNGKK-UHFFFAOYSA-N |
Canonical Smiles: | C1CCC(CC1)C(=O)N2CC3C4=CC=CC=C4CCN3C(=O)C2 |
Isomeric Smiles: | C1CCC(CC1)C(=O)N2CC3C4=CC=CC=C4CCN3C(=O)C2 |
Molecular Weight: | 312.4 |
Molecular Formula: | C19H24N2O2 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
praziquantel
Molecular Weight: | 312.4 |
Molecular Formula: | C19H24N2O2 |
Hydrogen Bond Donor Count: | 0 |
Hydrogen Bond Acceptor Count: | 2 |
Rotatable Bond Count: | 1 |
Heavy Atom Count: | 23 |
Complexity: | 472 |
Synonyms
praziquantel
| praziquantel | praziquantel |
|---|---|
praziquantel |
55268-74-1 |
Biltricide |
Droncit |
Pyquiton |
Cesol |
Embay 8440 |
Azinox |
2-(cyclohexanecarbonyl)-3,6,7,11b-tetrahydro-1H-pyrazino2,1-aisoquinolin-4-one |
2-(cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro-4H-pyrazino2,1-aisoquinolin-4-one |
MLS000038419 |
Praziquantel (Biltricide) |
MFCD00058531 |
SMR000037139 |
2-(cyclohexanecarbonyl)-1,2,3,6,7,11b-hexahydro-4H-pyrazino2,1-aisoquinolin-4-one |
2-(cyclohexanecarbonyl)-2,3,6,7-tetrahydro-1H-pyrazino2,1-aisoquinolin-4(11bH)-one |
135526-78-2 |
Cutter Tape Tabs |
2-(Cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro-4H-pyrazino(2,1-a)isoquinolin-4-one |
2-cyclohexanecarbonyl-1H,2H,3H,4H,6H,7H,11bH-piperazino2,1-aisoquinolin-4-one |
4H-Pyrazino(2,1-a)isoquinolin-4-one, 2-(cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro- |
4H-Pyrazino2,1-aisoquinolin-4-one, 2-(cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro- |
Praziquantelum |
Distocide |
Prazinon |
DSSTox_CID_1182 |
DSSTox_RID_75995 |
DSSTox_GSID_21182 |
Praziquantelum INN-Latin |
Cutter |
Biltricide (TN) |
CCRIS 4114 |
SR-01000003100 |
EINECS 259-559-6 |
BRN 0761557 |
Bay-8440 |
Praziquantel (JAN/USP/INN) |
EMBAY-8440 |
Praziquantel,(S) |
NCGC00016877-01 |
Prestwick_402 |
CAS-55268-74-1 |
(+-)-Praziquantel |
ACMC-20emeg |
Praziquantel USAN:USP:INN:BAN:JAN |
Spectrum_001119 |
Opera_ID_378 |
Prestwick0_000260 |
Prestwick1_000260 |
Prestwick2_000260 |
Prestwick3_000260 |
Spectrum2_001288 |
Spectrum3_000550 |
Spectrum4_000482 |
Spectrum5_001064 |
CHEMBL976 |
P 4668 |
cid_4891 |
Lopac0_000909 |
Oprea1_163497 |
SCHEMBL44153 |
BSPBio_000080 |
BSPBio_002199 |
KBioGR_000963 |
KBioSS_001599 |
5-24-03-00361 (Beilstein Handbook Reference) |
MLS000028528 |
MLS001201812 |
MLS001304085 |
MLS002548849 |
MLS006011880 |
DivK1c_000130 |
SPECTRUM1500494 |
SPBio_001295 |
SPBio_002299 |
Praziquantel-(cyclohexyl-d11) |
BPBio1_000088 |
DTXSID9021182 |
SCHEMBL16019896 |
BDBM74574 |
CHEBI:91583 |
HMS500G12 |
KBio1_000130 |
KBio2_001599 |
KBio2_004167 |
KBio2_006735 |
KBio3_001699 |
(S)-2-(Cyclohexanecarbonyl)-2,3,6,7-tetrahydro-1H-pyrazino2,1-aisoquinolin-4(11bH)-one |
NINDS_000130 |
HMS1568D22 |
HMS1920J06 |
HMS2090J19 |
HMS2092A09 |
HMS2095D22 |
HMS3259K07 |
HMS3262F20 |
HMS3655O19 |
HMS3712D22 |
Pharmakon1600-01500494 |
AMY16524 |
BCP17829 |
BCP28525 |
BCP30228 |
HY-B0244 |
WZB34336 |
Tox21_110660 |
Tox21_201950 |
Tox21_302927 |
Tox21_500909 |
CCG-39773 |
CP0098 |
NSC757285 |
Praziquantel, anthelminic, neurogenic |
s1691 |
STK030186 |
AKOS000541869 |
AKOS016398525 |
Tox21_110660_1 |
AC-8426 |
DB01058 |
LP00909 |
MCULE-1638759858 |
NC00468 |
NSC 757285 |
NSC-757285 |
SB49202 |
SDCCGSBI-0050884.P005 |
2-(Cyclohexylcarbonyl)-1,2,3,6,7-11b-hexahydro-4H-pyrazinoe(2,1a)isoquinolin-4-one |
IDI1_000130 |
NCGC00015818-04 |
NCGC00015818-05 |
NCGC00015818-06 |
NCGC00015818-07 |
NCGC00015818-08 |
NCGC00015818-11 |
NCGC00015818-12 |
NCGC00015818-14 |
NCGC00015818-15 |
NCGC00015818-26 |
NCGC00089733-02 |
NCGC00089733-03 |
NCGC00089733-04 |
NCGC00089733-05 |
NCGC00256422-01 |
NCGC00259499-01 |
NCGC00261594-01 |
AS-12459 |
BP166192 |
SY052322 |
SBI-0050884.P004 |
AB0011974 |
DB-052707 |
(S)-Praziquantel; Praziquantel, (S)-Isomer |
AB00052075 |
EU-0100909 |
FT-0630676 |
P2125 |
ST50904686 |
SW196645-3 |
1H-pyrazino2,1-aisoquinolin-4(11bH)-one |
2-(cyclohexanecarbonyl)-2,3,6,7-tetrahydro- |
C07367 |
D00471 |
J10194 |
AB00052075-13 |
AB00052075-15 |
AB00052075_16 |
AB00052075_17 |
Praziquantel, VETRANAL(TM), analytical standard |
268P741 |
A830562 |
Q424145 |
Praziquantel, Antibiotic for Culture Media Use Only |
Q-201612 |
SR-01000003100-3 |
SR-01000003100-5 |
SR-01000003100-7 |
BRD-A21858158-001-05-2 |
BRD-A21858158-001-16-9 |
SR-01000003100-16 |
F0037-0136 |
Z1563145961 |
Praziquantel, European Pharmacopoeia (EP) Reference Standard |
Praziquantel, United States Pharmacopeia (USP) Reference Standard |
10-(cyclohexylcarbonyl)-5,6,7,11a-tetrahydropiperazino2,1-aisoquinolin-8-one |
2-(Cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro- 4H-pyrazino2,1-a-isoquinolin-4-one |
2-(Cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro-4H-pyrazino-2,1- aisoquinolin-4-one |
2-(Cyclohexylcarbonyl)-1,2,3,6,7-11b-hexahydro-4H-pyrazino2,1-aisoquinolin-4-one |
2-cyclohexyl(oxo)methyl-3,6,7,11b-tetrahydro-1H-pyrazino2,1-aisoquinolin-4-one |
2-Cyclohexylcarbonyl-1,2,3,6,7,11b-hexahydro-4H-pyrazino(2,1-a)isoquinolin-4-one |
Praziquantel for system suitability, European Pharmacopoeia (EP) Reference Standard |
Praziquantel, Pharmaceutical Secondary Standard; Certified Reference Material |
Experimental Data
praziquantel
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33 | umol/L | -5 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
praziquantel
Statistics Data
praziquantel
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | -5 | 1 | 1 |
Statistics Data Visualization
praziquantel
