Compound Summary
Compound Information
172889-27-9
Compound Name: | 172889-27-9 |
Compound CID: | 4878 |
Synonyms: | 172889-27-9 pp2 PP 2 1-(tert-butyl)-3-(4-chlorophenyl)-1H-pyrazolo3,4-dpyrimidin-4-amine AG 1879 More... |
Iupac Name: | 1-tert-butyl-3-(4-chlorophenyl)pyrazolo[3,4-d]pyrimidin-4-amine |
InChI: | InChI=1S/C15H16ClN5/c1-15(2,3)21-14-11(13(17)18-8-19-14)12(20-21)9-4-6-10(16)7-5-9/h4-8H,1-3H3,(H2,17,18,19) |
InChIKey: | PBBRWFOVCUAONR-UHFFFAOYSA-N |
Canonical Smiles: | CC(C)(C)N1C2=NC=NC(=C2C(=N1)C3=CC=C(C=C3)Cl)N |
Isomeric Smiles: | CC(C)(C)N1C2=NC=NC(=C2C(=N1)C3=CC=C(C=C3)Cl)N |
Molecular Weight: | 301.77 |
Molecular Formula: | C15H16ClN5 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
172889-27-9
Molecular Weight: | 301.77 |
Molecular Formula: | C15H16ClN5 |
Hydrogen Bond Donor Count: | 1 |
Hydrogen Bond Acceptor Count: | 4 |
Rotatable Bond Count: | 2 |
Heavy Atom Count: | 21 |
Complexity: | 364 |
Synonyms
172889-27-9
| 172889-27-9 | 172889-27-9 |
|---|---|
172889-27-9 |
pp2 |
PP 2 |
1-(tert-butyl)-3-(4-chlorophenyl)-1H-pyrazolo3,4-dpyrimidin-4-amine |
AG 1879 |
1-tert-butyl-3-(4-chlorophenyl)-1H-pyrazolo3,4-dpyrimidin-4-amine |
1-tert-butyl-3-(4-chlorophenyl)pyrazolo3,4-dpyrimidin-4-amine |
AGL 1879 |
4-Amino-5-(4-chlorophenyl)-7-(t-butyl)pyrazolo3,4-dpyrimidine |
AG-1879 |
PP 2 (AG 1879) |
C15H16ClN5 |
CHEMBL406845 |
PP-2 |
CHEBI:78331 |
1qpe |
3-(4-chlorophenyl) 1-(1,1-dimethylethyl)-1H-pyrazolo3,4-dpyrimidin-4-amine |
InSolution™ PP2 |
4few |
AG1879 |
Kinome_2000 |
2zv9 |
BiomolKI_000052 |
PP 2 (enzyme inhibitor) |
BiomolKI2_000058 |
cid_4878 |
Oprea1_738267 |
BMK1-F4 |
BSPBio_001118 |
KBioGR_000458 |
KBioSS_000458 |
ksc-8-108 |
MLS000326622 |
SCHEMBL375322 |
GTPL9404 |
KBio2_000458 |
KBio2_003026 |
KBio2_005594 |
KBio3_000855 |
KBio3_000856 |
AOB6706 |
DTXSID60274447 |
Bio2_000399 |
Bio2_000879 |
HMS1362H19 |
HMS1792H19 |
HMS1990H19 |
HMS2182N11 |
HMS3267H08 |
HMS3403H19 |
HMS3412O04 |
HMS3652L14 |
HMS3676O04 |
HMS3747M11 |
KUC104577N |
PP2-AG1879 |
PP2(AGL 1879) |
AMY14185 |
BCP07605 |
EX-A2140 |
XGA88927 |
ZINC1383151 |
8913AA |
BDBM50142887 |
s7008 |
AKOS005078101 |
PP2, >=98% (HPLC) |
AG 1879,AGL 1879 |
CCG-100656 |
CS-1663 |
MB01880 |
1H-pyrazolo3,4-dpyrimidin-4-amine, 3-(4-chlorophenyl)-1-(1,1-dimethylethyl)- |
1H-Pyrazolo3,4-dpyrimidin-4-amine,3-(4-chlorophenyl)-1-(1,1-dimethylethyl)- |
IDI1_002154 |
QTL1_000068 |
NCGC00163385-01 |
NCGC00163385-02 |
NCGC00163385-03 |
NCGC00163385-04 |
NCGC00163385-14 |
11L-313S |
AC-32818 |
HY-13805 |
SMR000179218 |
AB0179191 |
DB-064881 |
FT-0711433 |
SW220209-1 |
EC-000.2432 |
VU0205247-1 |
C73316 |
K00048 |
PP2 - CAS 172889-27-9 |
J-010858 |
Q7120082 |
BRD-K95785537-001-03-3 |
BRD-K95785537-001-04-1 |
BRD-K95785537-001-10-8 |
1-tert-butyl-3-(4-chlorophenyl)pyrazolo4,5-epyrimidin-4-amine |
1-(tert-butyl)-3-(4-chlorophenyl)-4-aminopyrazolo3,4-dpyrimidine |
3-(4-chlorophenyl)1-tert-butyl-1h-pyrazolo3,4-dpyrimidin-4-amine |
4-amino-5-(4-chlorophenyl)-7-(tert-butyl)pyrazolo3,4-dpyrimidine |
1H-Pyrazolo3,4-dpyrimidin-4-amine, 3-(4-chlorophenyl)-1-(1,1-dimethylethyl)- (9CI) |
3-(4-chlorophenyl)1-(1,1-dimethylethyl)-1h-pyrazolo3,4-dpyrimidin-4-amine |
4-AMINO-3-(4-CHLOROPHENYL)-1-(T-BUTYL)-1H-PYRAZOLO3,4-DPYRIMIDINE |
9-(4-chlorophenyl)-7-tert-butyl-3,5,8-triaza-7-azoniabicyclo4.3.0nona-2,4,6,9-tetraen-2-amine |
Experimental Data
172889-27-9
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Drosophila melanogaster | 300 | umol/L | 22.8 | S | Oregon-R | 22363408 | Active |
Experimental Data Visualization
172889-27-9
Statistics Data
172889-27-9
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Drosophila melanogaster | 22.8 | 1 | 1 |
Statistics Data Visualization
172889-27-9
