Compound Summary
Compound Information
pinacidil
Compound Name: | pinacidil |
Compound CID: | 4826 |
Synonyms: | pinacidil 60560-33-0 Pinacidil anhydrous P 1134 1-cyano-2-(3,3-dimethylbutan-2-yl)-3-pyridin-4-ylguanidine More... |
Iupac Name: | 1-cyano-2-(3,3-dimethylbutan-2-yl)-3-pyridin-4-ylguanidine |
InChI: | InChI=1S/C13H19N5/c1-10(13(2,3)4)17-12(16-9-14)18-11-5-7-15-8-6-11/h5-8,10H,1-4H3,(H2,15,16,17,18) |
InChIKey: | IVVNZDGDKPTYHK-UHFFFAOYSA-N |
Canonical Smiles: | CC(C(C)(C)C)N=C(NC#N)NC1=CC=NC=C1 |
Isomeric Smiles: | CC(C(C)(C)C)N=C(NC#N)NC1=CC=NC=C1 |
Molecular Weight: | 245.32 |
Molecular Formula: | C13H19N5 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
pinacidil
Molecular Weight: | 245.32 |
Molecular Formula: | C13H19N5 |
Hydrogen Bond Donor Count: | 2 |
Hydrogen Bond Acceptor Count: | 3 |
Rotatable Bond Count: | 5 |
Heavy Atom Count: | 18 |
Complexity: | 327 |
Synonyms
pinacidil
| pinacidil | pinacidil |
|---|---|
pinacidil |
60560-33-0 |
Pinacidil anhydrous |
P 1134 |
1-cyano-2-(3,3-dimethylbutan-2-yl)-3-pyridin-4-ylguanidine |
N-Cyano-N-4-pyridinyl-N-(1,2,2-trimethylpropyl)guanidine |
CHEMBL1159 |
MLS000069377 |
(R,S)-Pinacidil |
S-1230 |
Guanidine, N-cyano-N-4-pyridinyl-N-(1,2,2-trimethylpropyl)- |
(+-)-Pinacidil |
Pinacidilum |
SMR000058360 |
(Z)-2-cyano-1-(3,3-dimethylbutan-2-yl)-3-(pyridin-4-yl)guanidine |
P-1134;S-1230 |
Pinacidilum INN-Latin |
P-154 |
Pinacidil INN |
(+/-)-Pinacidil |
SR-01000075340 |
SR-05000001757 |
NCGC00025188-04 |
EINECS 262-294-9 |
S 1230 |
2-Cyano-3-(4-pyridinyl)-1-(1,2,2-trimethylpropyl)guanidine |
Prestwick_396 |
ACMC-20mijl |
Spectrum_000387 |
SpecPlus_000759 |
Opera_ID_1844 |
Prestwick0_000246 |
Prestwick1_000246 |
Prestwick2_000246 |
Prestwick3_000246 |
Spectrum2_001739 |
Spectrum5_001372 |
CBiol_001878 |
Lopac0_001037 |
SCHEMBL65787 |
BSPBio_000032 |
BSPBio_001461 |
BSPBio_002360 |
KBioGR_000181 |
KBioSS_000181 |
KBioSS_000867 |
MLS002154248 |
DivK1c_006855 |
SPECTRUM2300270 |
SPBio_001818 |
SPBio_002251 |
BPBio1_000036 |
GTPL2412 |
SCHEMBL9260276 |
DTXSID7048249 |
Guanidine, N-cyano-N-4-pyridinyl-N-(1R)-1,2,2-trimethylpropyl- |
BCBcMAP01_000050 |
BDBM86245 |
CHEBI:91706 |
KBio1_001799 |
KBio2_000181 |
KBio2_000867 |
KBio2_002749 |
KBio2_003435 |
KBio2_005317 |
KBio2_006003 |
KBio3_000361 |
KBio3_000362 |
Bio1_000164 |
Bio1_000653 |
Bio1_001142 |
Bio2_000181 |
Bio2_000661 |
HMS1361J03 |
HMS1568B14 |
HMS1791J03 |
HMS1922L10 |
HMS1989J03 |
HMS2089C19 |
HMS2094G21 |
HMS2095B14 |
HMS2234F10 |
HMS3263O15 |
HMS3267P10 |
HMS3371H14 |
HMS3402J03 |
HMS3712B14 |
Pharmakon1600-02300270 |
NSC_4826 |
Tox21_501037 |
2657AH |
BDBM50103517 |
BDBM50240750 |
CCG-39493 |
NSC759588 |
AKOS001637331 |
AKOS025394868 |
CCG-205115 |
CCG-222341 |
DB06762 |
LP01037 |
MCULE-2402591602 |
NSC-759588 |
SDCCGSBI-0051008.P005 |
IDI1_033931 |
NCGC00015787-02 |
NCGC00015787-03 |
NCGC00015787-04 |
NCGC00015787-05 |
NCGC00015787-06 |
NCGC00015787-09 |
NCGC00025188-02 |
NCGC00025188-03 |
NCGC00025188-05 |
NCGC00025188-06 |
NCGC00025188-07 |
NCGC00025188-08 |
NCGC00025188-10 |
NCGC00095199-01 |
NCGC00095199-02 |
NCGC00095199-03 |
NCGC00095199-04 |
NCGC00188958-01 |
NCGC00247667-01 |
NCGC00261722-01 |
SBI-0051008.P004 |
CAS_85371-64-8 |
EU-0101037 |
FT-0630932 |
SW197742-2 |
AB00052442-04 |
AB00052442_05 |
AB00052442_06 |
371P648 |
560P330 |
Q821869 |
SR-01000075340-1 |
SR-01000075340-3 |
SR-05000001757-1 |
SR-05000001757-2 |
BRD-A43882281-001-06-4 |
BRD-A43882281-001-11-4 |
BRD-A58207013-001-01-2 |
3-cyano-2-(3,3-dimethylbutan-2-yl)-1-pyridin-4-ylguanidine |
N-cyano-N-(4-pyridyl)-N-(1,2,2-trimethylpropyl)guanidine" |
N-cyano-N-pyridin-4-yl-N-(1,2,2-trimethylpropyl)guanidine" |
()-N-Cyano-N-4-pyridinyl-N-(1,2,2-trimethylpropyl)guanidine |
4N-cyanoimino(1,2,2-trimethylpropylamino)methyl-4-pyridinamine(Pinacidil) |
4N-cyanoimino1,2,2-trimethyl-(1R)-propylaminomethyl-4-pyridinamine |
4N-cyanoimino1,2,2-trimethyl-(1S)-propylaminomethyl-4-pyridinamine |
N-cyano-N-pyridin-4-yl-N-(1R)-1,2,2-trimethylpropylguanidine" |
N-cyano-N-pyridin-4-yl-N-(1S)-1,2,2-trimethylpropylguanidine" |
N-Pyridin-4-yl-N-(1,2,2-trimethyl-propyl)-cyanoguanidine (pinacidil)" |
( inverted question mark)-N-Cyano-N-4-pyridinyl-N-(1,2,2-trimethylpropyl)-guanidine" |
N-cyano-N-pyridin-4-yl-N-(1,2,2-trimethylpropyl)guanidine ((+)-pinacidil)" |
N-cyano-N-pyridin-4-yl-N-(1,2,2-trimethylpropyl)guanidine (Pinacidil)" |
Experimental Data
pinacidil
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33 | umol/L | -9 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
pinacidil
Statistics Data
pinacidil
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | -9 | 1 | 1 |
Statistics Data Visualization
pinacidil
