Compound Summary
Compound Information
oxolinic acid
Compound Name: | oxolinic acid |
Compound CID: | 4628 |
Synonyms: | oxolinic acid 14698-29-4 Nidantin Dioxacin Emyrenil More... |
Iupac Name: | 5-ethyl-8-oxo-[1,3]dioxolo[4,5-g]quinoline-7-carboxylic acid |
InChI: | InChI=1S/C13H11NO5/c1-2-14-5-8(13(16)17)12(15)7-3-10-11(4-9(7)14)19-6-18-10/h3-5H,2,6H2,1H3,(H,16,17) |
InChIKey: | KYGZCKSPAKDVKC-UHFFFAOYSA-N |
Canonical Smiles: | CCN1C=C(C(=O)C2=CC3=C(C=C21)OCO3)C(=O)O |
Isomeric Smiles: | CCN1C=C(C(=O)C2=CC3=C(C=C21)OCO3)C(=O)O |
Molecular Weight: | 261.23 |
Molecular Formula: | C13H11NO5 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
oxolinic acid
Molecular Weight: | 261.23 |
Molecular Formula: | C13H11NO5 |
Hydrogen Bond Donor Count: | 1 |
Hydrogen Bond Acceptor Count: | 6 |
Rotatable Bond Count: | 2 |
Heavy Atom Count: | 19 |
Complexity: | 446 |
Synonyms
oxolinic acid
| oxolinic acid | oxolinic acid |
|---|---|
oxolinic acid |
14698-29-4 |
Nidantin |
Dioxacin |
Emyrenil |
Prodoxal |
Prodoxol |
Utibid |
Gramurin |
Oksaren |
Oxolinic |
Ossian |
Uroxol |
Acide oxolinique |
Uritrate |
Urotrate |
Oxoboi |
Pietil |
Starner |
Ultibid |
Acido oxolinico |
Uro-alvar |
Acidum oxolinicum |
Urinox |
5-Ethyl-8-oxo-5,8-dihydro-1,3dioxolo4,5-gquinoline-7-carboxylic acid |
NSC-110364 |
5-Ethyl-8-oxo-5,8-dihydro1,3dioxolo4,5-gquinoline-7-carboxylic acid |
5-ethyl-8-oxo-1,3dioxolo4,5-gquinoline-7-carboxylic acid |
NSC 110364 |
W 4565 |
1-Ethyl-6,7-methylenedioxy-4-quinolone-3-carboxylic acid |
UNII-L0A22B22FT |
MFCD00056775 |
1-Ethyl-1,4-dihydro-6,7-methylenedioxy-4-oxo-3-quinolinecarboxylic acid |
5-Ethyl-5,8-dihydro-8-oxo-1,3-dioxolo(4,5-g)quinoline-7-carboxylic acid |
1,3-Dioxolo4,5-gquinoline-7-carboxylic acid, 5-ethyl-5,8-dihydro-8-oxo- |
L0A22B22FT |
CHEBI:138856 |
1,3-Dioxolo(4,5-g)quinoline-7-carboxylic acid, 5-ethyl-5,8-dihydro-8-oxo- |
NSC110364 |
NCGC00015762-06 |
Cistopax |
Orthurine |
Tiurasin |
Acido ossolico |
CAS-14698-29-4 |
DSSTox_CID_1089 |
DSSTox_RID_75935 |
DSSTox_GSID_21089 |
Acido ossolico DCIT |
5-Ethyl-5,8-dihydro-8-oxo-1,3-dioxolo4,5-gquinoline-7-carboxylic acid |
5-ethyl-8-oxo-5-hydro-2H-1,3-dioxoleno4,5-gquinoline-7-carboxylic acid |
Acide oxolinique INN-French |
Acido oxolinico INN-Spanish |
Acidum oxolinicum INN-Latin |
CCRIS 6301 |
HSDB 3243 |
SR-01000076042 |
EINECS 238-750-8 |
BRN 0620635 |
Inoxyl |
oxolinic-acid |
Oxolinic acid USAN:INN:BAN |
S-0208 |
Aqualinic (TN) |
quinolone antibiotic |
Prestwick_629 |
Spectrum_001397 |
Oxolinic acid impurity B |
Prestwick0_000193 |
Prestwick1_000193 |
Prestwick2_000193 |
Prestwick3_000193 |
Spectrum2_000933 |
Spectrum3_001490 |
Spectrum4_000073 |
Spectrum5_001176 |
Lopac-O-0877 |
Oxolinic acid (USAN/INN) |
Lopac0_000952 |
Oprea1_169598 |
SCHEMBL24445 |
BSPBio_000145 |
BSPBio_003079 |
KBioGR_000625 |
KBioSS_001877 |
MLS000028501 |
DivK1c_000659 |
SPECTRUM1502030 |
SPBio_000866 |
SPBio_002066 |
BPBio1_000161 |
CHEMBL416755 |
ZINC1875 |
DTXSID1021089 |
HMS502A21 |
KBio1_000659 |
KBio2_001877 |
KBio2_004445 |
KBio2_007013 |
KBio3_002579 |
AOB5349 |
NINDS_000659 |
HMS1568H07 |
HMS1921F12 |
HMS2092P09 |
HMS2095H07 |
HMS3262P06 |
HMS3712H07 |
Oxolinic acid, analytical standard |
Pharmakon1600-01502030 |
Oxolinic acid, quinolone antibiotic |
ACT03284 |
HY-B1002 |
Tox21_110216 |
Tox21_202787 |
Tox21_500952 |
AC8065 |
BBL009934 |
CCG-39666 |
NSC758177 |
s4537 |
SBB012469 |
STK801351 |
5,8-Dihydro-5-ethyl-8-oxo-1,3-dioxolo4,5-gquinoline-7-carboxylic acid |
AKOS000282622 |
Tox21_110216_1 |
CS-4499 |
DB13627 |
LP00952 |
MCULE-2131347036 |
NSC-758177 |
SDCCGSBI-0050926.P004 |
IDI1_000659 |
NCGC00015762-01 |
NCGC00015762-02 |
NCGC00015762-03 |
NCGC00015762-04 |
NCGC00015762-05 |
NCGC00015762-07 |
NCGC00015762-08 |
NCGC00015762-09 |
NCGC00015762-10 |
NCGC00015762-11 |
NCGC00015762-13 |
NCGC00015762-17 |
NCGC00093361-02 |
NCGC00093361-03 |
NCGC00093361-04 |
NCGC00093361-05 |
NCGC00260333-01 |
NCGC00261637-01 |
AS-12087 |
SMR000058314 |
ST067125 |
SY066716 |
SBI-0050926.P003 |
DB-042865 |
EU-0100952 |
FT-0637128 |
VU0243182-3 |
D02301 |
O 0877 |
WLN: T C566 DO FO JN MV EHJ J2 LVQ |
698O294 |
A808577 |
Q287840 |
SR-01000076042-1 |
SR-01000076042-4 |
SR-01000076042-6 |
W-108119 |
BRD-K73394555-001-08-6 |
5-Ethyl-5,3-dioxolo4,5-gquinoline-7-carboxylic acid |
F3351-0487 |
1-Ethyl-1,7-methylenedioxy-4-oxo-3-quinolinecarboxylic acid |
Oxolinic acid, European Pharmacopoeia (EP) Reference Standard |
1,5-gquinoline-7-carboxylic acid, 5-ethyl-5,8-dihydro-8-oxo- |
1.4-Dihydro-1-ethyl-6,7-methylenedioxy-4-oxoquinoline-3-carboxylic acid |
5-Ethy1-5,8-dihydro-8-oxo-1,3-dioxolo4,5quinoline-7-carboxylic acid |
5-ETHYL-8-OXO-2H,5H,8H-1,3DIOXOLO4,5-GQUINOLINE-7-CARBOXYLIC ACID |
5-Ethyl-8-oxo-5,8-dihydro1,3dioxolo4,5-gquinoline-7-carboxylic acid # |
W-4565; 5,8-Dihydro-5-ethyl-8-oxo-1,3-dioxolo4,5-gquinoline-7-carboxylic acid |
Experimental Data
oxolinic acid
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33 | umol/L | 8 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
oxolinic acid
Statistics Data
oxolinic acid
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 8 | 1 | 1 |
Statistics Data Visualization
oxolinic acid
