Compound Summary
Compound Information
nilutamide
Compound Name: | nilutamide |
Compound CID: | 4493 |
Synonyms: | nilutamide 63612-50-0 Anandron Nilandron 5,5-dimethyl-3-(4-nitro-3-(trifluoromethyl)phenyl)imidazolidine-2,4-dione More... |
Iupac Name: | 5,5-dimethyl-3-[4-nitro-3-(trifluoromethyl)phenyl]imidazolidine-2,4-dione |
InChI: | InChI=1S/C12H10F3N3O4/c1-11(2)9(19)17(10(20)16-11)6-3-4-8(18(21)22)7(5-6)12(13,14)15/h3-5H,1-2H3,(H,16,20) |
InChIKey: | XWXYUMMDTVBTOU-UHFFFAOYSA-N |
Canonical Smiles: | CC1(C(=O)N(C(=O)N1)C2=CC(=C(C=C2)[N+](=O)[O-])C(F)(F)F)C |
Isomeric Smiles: | CC1(C(=O)N(C(=O)N1)C2=CC(=C(C=C2)[N+](=O)[O-])C(F)(F)F)C |
Molecular Weight: | 317.22 |
Molecular Formula: | C12H10F3N3O4 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
nilutamide
Molecular Weight: | 317.22 |
Molecular Formula: | C12H10F3N3O4 |
Hydrogen Bond Donor Count: | 1 |
Hydrogen Bond Acceptor Count: | 7 |
Rotatable Bond Count: | 1 |
Heavy Atom Count: | 22 |
Complexity: | 515 |
Synonyms
nilutamide
| nilutamide | nilutamide |
|---|---|
nilutamide |
63612-50-0 |
Anandron |
Nilandron |
5,5-dimethyl-3-(4-nitro-3-(trifluoromethyl)phenyl)imidazolidine-2,4-dione |
Nilutamida |
Nilutamidum |
5,5-dimethyl-3-4-nitro-3-(trifluoromethyl)phenylimidazolidine-2,4-dione |
RU-23908 |
RU 23908 |
5,5-Dimethyl-3-(alpha,alpha,alpha-trifluoro-4-nitro-m-tolyl)hydantoin |
Nilandrone |
UNII-51G6I8B902 |
Nilandron;RU 23908 |
CHEMBL1274 |
CHEBI:7573 |
Nilutamidum Latin |
Nilutamida Spanish |
2,4-Imidazolidinedione,5,5-dimethyl-3-4-nitro-3-(trifluoromethyl)phenyl- |
5,5-Dimethyl-3-(4-nitro-3-(trifluoromethyl)phenyl)-2,4-imidazolidinedione |
5,5-Dimethyl-3-4-nitro-3-(trifluoromethyl)phenyl-2,4-imidazolidinedione |
MFCD00864670 |
51G6I8B902 |
NCGC00015754-08 |
CAS-63612-50-0 |
DSSTox_CID_14165 |
DSSTox_RID_79118 |
DSSTox_GSID_34165 |
Nilutamide USAN:INN:BAN |
5,5-Dimethyl-3-(4-nitro-3-(trifluoromethyl)-phenyl)imidazolidine-2,4-dione |
5,5-dimethyl-3-4-nitro-3-(trifluoromethyl)phenyl-1,3-diazolidine-2,4-dione |
Nilandron (TN) |
RU 23908-10 |
SR-01000076034 |
Nilutamide (USAN/INN) |
BRN 0841906 |
Nilutamide, solid |
1-(3-Trifluoromethyl-4-nitrophenyl)-4,4-dimethylimidazolidine-2,5-dione |
Spectrum_001625 |
Tocris-1759 |
SpecPlus_000902 |
Prestwick0_000928 |
Prestwick1_000928 |
Prestwick2_000928 |
Prestwick3_000928 |
Spectrum2_001973 |
Spectrum3_001633 |
Spectrum4_000600 |
Spectrum5_001512 |
Lopac-N-8534 |
N 8534 |
2,4-IMIDAZOLIDINEDIONE, 5,5-DIMETHYL-3-(4-NITRO-3-(TRIFLUOROMETHYL)PHENYL)- |
BIDD:PXR0177 |
Lopac0_000879 |
SCHEMBL12670 |
BSPBio_000836 |
BSPBio_003325 |
KBioGR_001100 |
KBioSS_002105 |
MLS002154066 |
BIDD:GT0683 |
DivK1c_006998 |
SPECTRUM1504152 |
SPBio_002125 |
SPBio_003015 |
BPBio1_000920 |
GTPL2864 |
DTXSID3034165 |
KBio1_001942 |
KBio2_002105 |
KBio2_004673 |
KBio2_007241 |
KBio3_002545 |
BCPP000148 |
HMS1570J18 |
HMS1922F03 |
HMS2093A10 |
HMS2097J18 |
HMS2230E03 |
HMS3262P19 |
HMS3268C18 |
HMS3369I02 |
HMS3414N15 |
HMS3678N13 |
HMS3714J18 |
Pharmakon1600-01504152 |
AMY32529 |
BCP26617 |
ZINC3874498 |
Tox21 110213 |
Tox21_110213 |
Tox21_301589 |
Tox21_500879 |
BDBM50135912 |
CCG-39427 |
NSC758683 |
s4836 |
SBB067297 |
STK633161 |
AKOS005565152 |
AKOS025147305 |
Tox21_110213_1 |
AC-5260 |
BCP9000990 |
DB00665 |
LP00879 |
MCULE-3215206804 |
NSC 758683 |
NSC-758683 |
RU23908 |
SB19036 |
SDCCGSBI-0050854.P004 |
NCGC00015754-01 |
NCGC00015754-02 |
NCGC00015754-03 |
NCGC00015754-04 |
NCGC00015754-05 |
NCGC00015754-06 |
NCGC00015754-07 |
NCGC00015754-09 |
NCGC00015754-10 |
NCGC00015754-11 |
NCGC00015754-12 |
NCGC00015754-15 |
NCGC00015754-16 |
NCGC00015754-22 |
NCGC00025280-01 |
NCGC00025280-02 |
NCGC00025280-03 |
NCGC00025280-04 |
NCGC00025280-05 |
NCGC00025280-06 |
NCGC00025280-07 |
NCGC00025280-08 |
NCGC00255271-01 |
NCGC00261564-01 |
AS-14123 |
BN166184 |
HY-13702 |
K002 |
SMR001233381 |
ST075550 |
SBI-0050854.P003 |
AB0013969 |
AB00053180 |
CS-0007719 |
EU-0100879 |
FT-0630740 |
C08164 |
D00965 |
AB00053180_07 |
612N500 |
A834440 |
L000759 |
Q3877030 |
RU-23908;RU 23908;RU23908 |
SR-01000076034-1 |
SR-01000076034-3 |
SR-01000076034-5 |
SR-01000076034-6 |
SR-01000076034-9 |
BRD-K23566484-001-05-2 |
BRD-K23566484-001-09-4 |
Z2417927201 |
Nilutamide, European Pharmacopoeia (EP) Reference Standard |
1-(3-trifluoromethyl-4-nitrophenyl)-4,4-dimethyl-imidazoline-2,5-dione" |
1-(3-trifluoromethyl-4-nitrophenyl)4,4-dimethyl-imidazoline-2,5-dione" |
1-(3-trifluoromethyl-4nitrophenyl)-4,4-dimethyl-imidazoline-2,5-dione" |
1-(3trifluoromethyl-4-nitropheyl)-4,4-dimethyl-imidazoline-2,5-dione" |
1-(3-trifluoromethyl-4-nitrophenyl)-4,4-dimethyl-imidazoline-2,5-dione |
1-(3-trifluoromethyl-4-nitro-phenyl)-4,4-dimethyl imidazolidine-2,5-dione |
1-(3-trifluoromethyl-4-nitro-phenyl)-4,4-dimethyl-imidazolidine-2,5-dione |
1-(3-trifluoromethyl-4-nitro-phenyl)-4,4-dimethyl-imidazoline-2,5-dione |
1-(3-trifluoromethyl-4-nitrophenyl)-4,4-dimethyl-imidazoline-2,5-dione |
3-(3-(trifluoromethyl)-4-nitrophenyl)-5,5-dimethylimidazolidine-2,4-dione |
5,5-Dimethyl-3-(4-nitro-3-trifluoromethyl-phenyl)-imidazolidine-2,4-dione |
diethyl1,4-dihydro-2,6-dimethyl-1,4-diphenyl-3,5-pyridinedicarboxylate |
5,5-dimethyl-3-4-nitro-3-(trifluoromethyl)phenyl-imidazolidine-2,4-dione |
Experimental Data
nilutamide
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33 | umol/L | -7 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
nilutamide
Statistics Data
nilutamide
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | -7 | 1 | 1 |
Statistics Data Visualization
nilutamide
