Compound Summary
Compound Information
Karakoline
Compound Name: | Karakoline |
Compound CID: | 441742 |
Synonyms: | Karakoline Carmichaeline Karacoline Carmicheline 39089-30-0 More... |
Iupac Name: | (1S,2R,3R,4S,5S,6S,8S,9S,13R,16S,17R)-11-ethyl-6-methoxy-13-methyl-11-azahexacyclo[7.7.2.12,5.01,10.03,8.013,17]nonadecane-4,8,16-triol |
InChI: | InChI=1S/C22H35NO4/c1-4-23-10-20(2)6-5-16(24)22-12-7-11-14(27-3)9-21(26,17(12)18(11)25)13(19(22)23)8-15(20)22/h11-19,24-26H,4-10H2,1-3H3/t11-,12-,13+,14+,15-,16+,17-,18+,19?,20+,21+,22-/m1/s1 |
InChIKey: | HKQZUYOVMYOFIT-VHNBHZRZSA-N |
Canonical Smiles: | CCN1CC2(CCC(C34C2CC(C31)C5(CC(C6CC4C5C6O)OC)O)O)C |
Isomeric Smiles: | CCN1C[C@@]2(CC[C@@H]([C@@]34[C@@H]2C[C@@H](C31)[C@]5(C[C@@H]([C@H]6C[C@@H]4[C@@H]5[C@H]6O)OC)O)O)C |
Molecular Weight: | 377.5 |
Molecular Formula: | C22H35NO4 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
Karakoline
Molecular Weight: | 377.5 |
Molecular Formula: | C22H35NO4 |
Hydrogen Bond Donor Count: | 3 |
Hydrogen Bond Acceptor Count: | 5 |
Rotatable Bond Count: | 2 |
Heavy Atom Count: | 27 |
Complexity: | 673 |
Synonyms
Karakoline
| Karakoline | Karakoline |
|---|---|
Karakoline |
Carmichaeline |
Karacoline |
Carmicheline |
39089-30-0 |
Aconitane-1,8,14-triol, 20-ethyl-16-methoxy-4-methyl-, (1-alpha,14-alpha,16-beta)- |
20-ethyl-16beta-methoxy-4-methylaconitane-1alpha,8,14alpha-triol |
CHEBI:6113 |
DTXSID20959905 |
C08693 |
Q27107081 |
Experimental Data
Karakoline
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33 | umol/L | 0 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
Karakoline
Statistics Data
Karakoline
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 0 | 1 | 1 |
Statistics Data Visualization
Karakoline
