Compound Summary
Compound Information
L-Carnosine
Compound Name: | L-Carnosine |
Compound CID: | 439224 |
Synonyms: | L-Carnosine Carnosine 305-84-0 beta-Alanyl-L-histidine Karnozin More... |
Iupac Name: | (2S)-2-(3-aminopropanoylamino)-3-(1H-imidazol-5-yl)propanoic acid |
InChI: | InChI=1S/C9H14N4O3/c10-2-1-8(14)13-7(9(15)16)3-6-4-11-5-12-6/h4-5,7H,1-3,10H2,(H,11,12)(H,13,14)(H,15,16)/t7-/m0/s1 |
InChIKey: | CQOVPNPJLQNMDC-ZETCQYMHSA-N |
Canonical Smiles: | C1=C(NC=N1)CC(C(=O)O)NC(=O)CCN |
Isomeric Smiles: | C1=C(NC=N1)C[C@@H](C(=O)O)NC(=O)CCN |
Molecular Weight: | 226.23 |
Molecular Formula: | C9H14N4O3 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
L-Carnosine
Molecular Weight: | 226.23 |
Molecular Formula: | C9H14N4O3 |
Hydrogen Bond Donor Count: | 4 |
Hydrogen Bond Acceptor Count: | 5 |
Rotatable Bond Count: | 6 |
Heavy Atom Count: | 16 |
Complexity: | 259 |
Synonyms
L-Carnosine
| L-Carnosine | L-Carnosine |
|---|---|
L-Carnosine |
Carnosine |
305-84-0 |
beta-Alanyl-L-histidine |
Karnozin |
Ignotine |
Karnozzn |
L-Ignotine |
N-2-M |
UNII-8HO6PVN24W |
L-Histidine, beta-alanyl- |
Polaprezinc |
CHEBI:15727 |
Nalpha-(beta-alanyl)-L-histidine |
NSC 524045 |
(2S)-2-(3-aminopropanamido)-3-(1H-imidazol-4-yl)propanoic acid |
BRN 0087671 |
8HO6PVN24W |
(3-aminopropanoyl)-L-histidine |
L-Histidine, N-.beta.-alanyl- |
L-HISTIDINE, N-beta-ALANYL- |
beta-Alanylhistidine |
MFCD00005207 |
L-Histidine, beta-alanyl-, homopolymer |
Z-103 |
Z 103 |
N-beta-alanyl-L-histidine |
(2S)-2-(3-aminopropanoylamino)-3-imidazol-4-ylpropanoic acid |
(2~{S})-2-(3-azanylpropanoylamino)-3-(1~{H}-imidazol-4-yl)propanoic acid |
1370422-07-3 |
.beta.-Alanyl-L-histidine |
Sevitin |
betaAla-His |
b-Alanylhistidine |
beta-Ala-His-OH |
EINECS 206-169-9 |
3-Chloromandelicacid |
b-Alanyl-L-histidine |
beta-alanyl-l-histidin |
.beta.-Alanylhistidine |
Spectrum_001178 |
N-b-alanyl-L-Histidine |
SpecPlus_000374 |
Spectrum2_000454 |
Spectrum3_001212 |
Spectrum4_001673 |
Spectrum5_000605 |
3-aminopropionyl-histidine |
bmse000246 |
bmse001002 |
C00386 |
N-(b-Alanyl)-L-histidine |
SCHEMBL33769 |
BSPBio_002624 |
KBioGR_002225 |
KBioSS_001658 |
4-25-00-04381 (Beilstein Handbook Reference) |
DivK1c_006470 |
SPECTRUM1500944 |
N-(3-Aminopropanoyl)histidine |
SPBio_000528 |
CHEMBL242948 |
GTPL4559 |
KBio1_001414 |
KBio2_001658 |
KBio2_004226 |
KBio2_006794 |
KBio3_002124 |
DTXSID80879594 |
L-Carnosine, ~99%, crystalline |
TNP00340 |
ZINC2040854 |
N(alpha)-(beta-alanyl)-L-histidine |
(2S)-2-(3-aminopropanoylamino)-3-(1H-imidazol-5-yl)propanoic acid |
BDBM50485554 |
CCG-38696 |
SBB003316 |
STL466172 |
AKOS010421481 |
AKOS015963345 |
CS-W014210 |
DB11695 |
HY-W013494 |
MCULE-5739145561 |
SDCCGMLS-0066726.P001 |
NCGC00017390-01 |
NCGC00017390-02 |
NCGC00142487-01 |
AC-17084 |
AC-19690 |
AC-31940 |
AS-12570 |
ST057076 |
A0222 |
L-Carnosine, Vetec(TM) reagent grade, 98% |
S5226 |
H11980 |
305C840 |
Q413822 |
SR-05000002473 |
SR-05000002473-1 |
(2S)-2-(3-aminopropanamido)-3-(1H-imidazol-5-yl)propanoic acid |
(S)-2-(3-aminopropanamido)-3-(1H-imidazol-4-yl)propanoic acid |
8V0 |
Experimental Data
L-Carnosine
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Drosophila melanogaster | 0.2 | mg/L | 42.4 | 36.9 | -0.13 | NS | D-32 | FEMALES | 12447464 | Inactive | |||
| Caenorhabditis elegans | 0.1 | mM | 14 | S | N2 | 25643626 | Active | ||||||
| Caenorhabditis elegans | 0.01 | mM | 1 | NS | N2 | 25643626 | Inactive | ||||||
| Drosophila melanogaster | 0.02 | mg/L | 42.4 | 34.9 | -0.18 | NS | D-32 | FEMALES | 12447464 | Inactive | |||
| Drosophila melanogaster | 20 | mg/L | 29.2 | 36.3 | 0.24 | S | D-32 | MALES | 12447464 | Active | |||
| Drosophila melanogaster | 0.02 | mg/L | 29.2 | 34.9 | 0.2 | S | D-32 | MALES | 12447464 | Active | |||
| Drosophila melanogaster | 50 | mg/L | 30.21 | 36.37 | 0.2 | 58 | 63 | 0.09 | S | MALES | 20681748 | Active | |
| Drosophila melanogaster | 50 | mg/L | 21.35 | 21.93 | 0.03 | 52 | 48 | -0.08 | NS | FEMALES | 20681748 | Inactive | |
| Drosophila melanogaster | 0.2 | mg/L | 29.2 | 36.9 | 0.26 | S | D-32 | MALES | 12447464 | Active | |||
| Drosophila melanogaster | 20 | mg/L | 42.4 | 36.3 | -0.14 | NS | D-32 | FEMALES | 12447464 | Inactive | |||
| Caenorhabditis elegans | 1 | mM | 11 | S | N2 | 25643626 | Active |
Experimental Data Visualization
L-Carnosine
Statistics Data
L-Carnosine
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 14 | 1 | 3 | |
| Drosophila melanogaster | 0.26 | 0.09 | 2 | 8 |
Statistics Data Visualization
L-Carnosine
