Compound Summary
Compound Information
mitotane
Compound Name: | mitotane |
Compound CID: | 4211 |
Synonyms: | mitotane 53-19-0 Mitotan Lysodren o,p-DDD More... |
Iupac Name: | 1-chloro-2-[2,2-dichloro-1-(4-chlorophenyl)ethyl]benzene |
InChI: | InChI=1S/C14H10Cl4/c15-10-7-5-9(6-8-10)13(14(17)18)11-3-1-2-4-12(11)16/h1-8,13-14H |
InChIKey: | JWBOIMRXGHLCPP-UHFFFAOYSA-N |
Canonical Smiles: | C1=CC=C(C(=C1)C(C2=CC=C(C=C2)Cl)C(Cl)Cl)Cl |
Isomeric Smiles: | C1=CC=C(C(=C1)C(C2=CC=C(C=C2)Cl)C(Cl)Cl)Cl |
Molecular Weight: | 320 |
Molecular Formula: | C14H10Cl4 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
mitotane
Molecular Weight: | 320 |
Molecular Formula: | C14H10Cl4 |
Hydrogen Bond Donor Count: | 0 |
Hydrogen Bond Acceptor Count: | 0 |
Rotatable Bond Count: | 3 |
Heavy Atom Count: | 18 |
Complexity: | 248 |
Synonyms
mitotane
| mitotane | mitotane |
|---|---|
mitotane |
53-19-0 |
Mitotan |
Lysodren |
o,p-DDD |
Chlodithane |
Chloditan |
Khlodithan |
Chlodithan |
1-(2-Chlorophenyl)-1-(4-chlorophenyl)-2,2-dichloroethane |
2,4-Ddd |
Mitotano |
1-Chloro-2-2,2-dichloro-1-(4-chlorophenyl)ethylbenzene |
NCI-C04933 |
o,p-TDE" |
2,4-Dichlorodiphenyldichloroethane |
Benzene, 1-chloro-2-2,2-dichloro-1-(4-chlorophenyl)ethyl- |
1-Chloro-2-(2,2-dichloro-1-(4-chlorophenyl)ethyl)benzene |
o,p-Dichlorodiphenyldichloroethane" |
2,4-Dichlorophenyldichlorethane |
CB 313 |
NSC 38721 |
1,1-Dichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane |
2-(2-Chlorophenyl)-2-(4-chlorophenyl)-1,1-dichloroethane |
2-(o-Chlorophenyl)-2-(p-chlorophenyl)-1,1-dichloroethane |
1,1-Dichloro-2,2-bis(2,4-dichlorophenyl)ethane |
NSC38721 |
1,1-Dichloro-2-(p-chlorophenyl)-2-(o-chlorophenyl)ethane |
2,2-Bis(2-chlorophenyl-4-chlorophenyl)-1,1-dichloroethane |
CB-313 |
NSC-38721 |
2,4-DDD;o,p-DDD |
Ethane, 1,1-dichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)- |
Ethane, 2-(o-chlorophenyl)-2-(p-chlorophenyl)-1,1-dichloro- |
Benzene, 1-chloro-2-(2,2-dichloro-1-(4-chlorophenyl)ethyl)- |
2,4 inverted exclamation marka-DDD |
MFCD00000850 |
Mitotanum INN-Latin |
o,p-Tde |
NCGC00015226-07 |
1-chloro-4-2,2-dichloro-1-(2-chlorophenyl)ethylbenzene |
Mitotanum |
DSSTox_CID_372 |
Mitotano INN-Spanish |
DSSTox_RID_75548 |
DSSTox_GSID_20372 |
2,4-(2,2-dichloroethane-1,1-diyl)bis(chlorobenzene) |
Opeprim |
Mitotane (Lsodren) |
CB313 |
DDD, o,p- |
CAS-53-19-0 |
Lysodren (TN) |
SMR000326696 |
CCRIS 4397 |
HSDB 3240 |
SR-01000075751 |
EINECS 200-166-6 |
(o,p)-DDD |
Mitotane (JAN/USP/INN) |
BRN 2056007 |
AI3-07575 |
Prestwick_75 |
Ethane,1-dichloro- |
Mitotane (Lysodren) |
Mitotane USAN:USP:INN:BAN:JAN |
(2,4-Dichlorodiphenyl)dichloroethane |
Spectrum_001959 |
DDD-o,p |
(+-)-1,1-Dichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane |
Spectrum2_000916 |
Spectrum3_000869 |
Spectrum4_000709 |
Spectrum5_002060 |
C 3010 |
(o,p)-DDD |
SCHEMBL4040 |
CHEMBL1670 |
Lopac0_000251 |
WLN: GYGYR BG&R DG |
BSPBio_002517 |
KBioGR_001237 |
KBioSS_002513 |
SPECTRUM330082 |
MLS001335899 |
MLS001335900 |
MLS002152914 |
MLS002153233 |
DivK1c_000703 |
SPBio_000792 |
CHEBI:6954 |
GTPL6957 |
Mitotane, >=98% (HPLC) |
DTXSID9020372 |
2,4-DDD, analytical standard |
HMS502D05 |
KBio1_000703 |
KBio2_002505 |
KBio2_005073 |
KBio2_007641 |
KBio3_002017 |
NINDS_000703 |
HMS1923K19 |
HMS2091E07 |
HMS2232C16 |
HMS3260D04 |
HMS3369H10 |
HMS3655G06 |
HMS3715H07 |
HMS3869F13 |
Pharmakon1600-00330082 |
BCP11663 |
Tox21_110103 |
Tox21_302804 |
Tox21_500251 |
CCG-40014 |
NSC755849 |
s1732 |
1,2-bis(2,4-dichlorophenyl)ethane |
AKOS006028802 |
Benzene, 1-chloro-2-(2,2-dichloro-1-(4-chlorophenyl)ethyl)-, (+-)- |
Tox21_110103_1 |
CS-1500 |
DB00648 |
LP00251 |
MCULE-2068358149 |
NSC-755849 |
SDCCGSBI-0050239.P006 |
IDI1_000703 |
NCGC00015226-02 |
NCGC00015226-03 |
NCGC00015226-04 |
NCGC00015226-05 |
NCGC00015226-06 |
NCGC00015226-08 |
NCGC00015226-09 |
NCGC00015226-10 |
NCGC00015226-11 |
NCGC00015226-12 |
NCGC00091374-01 |
NCGC00091374-02 |
NCGC00091374-03 |
NCGC00091374-04 |
NCGC00091374-05 |
NCGC00091374-06 |
NCGC00256452-01 |
NCGC00260936-01 |
2,4-DDD 10 microg/mL in Cyclohexane |
AS-11690 |
HY-13690 |
NCI60_003688 |
2,4-DDD 100 microg/mL in Cyclohexane |
SBI-0050239.P004 |
AB0010565 |
EU-0100251 |
FT-0605518 |
ST51016017 |
SW199619-3 |
EN300-37268 |
2,4 inverted exclamation marka-DDD;o,p-DDD" |
2,4-DDD, PESTANAL(R), analytical standard |
C75491 |
D00420 |
AB00052337-09 |
AB00052337_10 |
000M850 |
Q417465 |
SR-01000075751-1 |
SR-01000075751-3 |
SR-01000075751-6 |
Z425389592 |
1-(o-Chlorophenyl)-1-(p-chlorophenyl)-2,2-dichloroethane |
1-2,2-dichloro-1-(4-chlorophenyl)ethyl-2-chlorobenzene |
Ethane,1-dichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)- |
1-Chloro-2-2,2-dichloro-1-(4-chlorophenyl)ethylbenzene # |
Mitotane, United States Pharmacopeia (USP) Reference Standard |
Ethane, 1,1-dichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)- (8CI) |
1-(2-Chlorophenyl)-1-(4-chlorophenyl)-2,2-dichloroethane, analytical standard |
o,p-DDD|||1-(2-Chlorophenyl)-1-(4-chlorophenyl)-2,2-dichloroethane|||Mitotane |
1-(2-Chlorophenyl)-1-(4-chlorophenyl)-2,2-dichloroethane for diagnostic uses (cancer investigation), >=98% (HPLC) |
1-(2-Chlorophenyl)-1-(4-chlorophenyl)-2,2-dichloroethane, for diagnostic uses (cancer investigation), >=98% (HPLC) |
Experimental Data
mitotane
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33 | umol/L | 8 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
mitotane
Statistics Data
mitotane
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 8 | 1 | 1 |
Statistics Data Visualization
mitotane
