Compound Summary
Compound Information
mianserin
Compound Name: | mianserin |
Compound CID: | 4184 |
Synonyms: | mianserin Mianserine 24219-97-4 Mianseryna Polish Mianserina More... |
Iupac Name: | 5-methyl-2,5-diazatetracyclo[13.4.0.02,7.08,13]nonadeca-1(19),8,10,12,15,17-hexaene |
InChI: | InChI=1S/C18H20N2/c1-19-10-11-20-17-9-5-3-7-15(17)12-14-6-2-4-8-16(14)18(20)13-19/h2-9,18H,10-13H2,1H3 |
InChIKey: | UEQUQVLFIPOEMF-UHFFFAOYSA-N |
Canonical Smiles: | CN1CCN2C(C1)C3=CC=CC=C3CC4=CC=CC=C42 |
Isomeric Smiles: | CN1CCN2C(C1)C3=CC=CC=C3CC4=CC=CC=C42 |
Molecular Weight: | 264.4 |
Molecular Formula: | C18H20N2 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
mianserin
Molecular Weight: | 264.4 |
Molecular Formula: | C18H20N2 |
Hydrogen Bond Donor Count: | 0 |
Hydrogen Bond Acceptor Count: | 2 |
Rotatable Bond Count: | 0 |
Heavy Atom Count: | 20 |
Complexity: | 342 |
Synonyms
mianserin
| mianserin | mianserin |
|---|---|
mianserin |
Mianserine |
24219-97-4 |
Mianseryna Polish |
Mianserina |
Mianserinum |
Mianseryna |
Norval |
Mianserine INN-French |
Mianserinum INN-Latin |
Mianserina INN-Spanish |
2-Methyl-1,2,3,4,10,14b-hexahydrodibenzoc,fpyrazino1,2-aazepine |
1,2,3,4,10,14b-Hexahydro-2-methyldibenzo(c,f)pyrazino(1,2-a)azepine |
Lerivon |
CHEBI:51137 |
CHEMBL6437 |
NCGC00015656-06 |
DSSTox_CID_3317 |
Mianserin INN:BAN |
Dibenzoc,fpyrazino1,2-aazepine, 1,2,3,4,10,14b-hexahydro-2-methyl- |
DSSTox_RID_76974 |
DSSTox_GSID_23317 |
Mianserin-d3 Dihydrochloride |
1,2,3,4,10,14b-hexahydro-2-methyldibenzoc,fpyrazino1,2-aazepine |
Dibenzo(c,f)pyrazino(1,2-a)azepine, 1,2,3,4,10,14b-hexahydro-2-methyl- |
Mianserin (INN) |
CAS-24219-97-4 |
Tolvon (TN) |
HSDB 7182 |
EINECS 246-088-6 |
BRN 0755346 |
Lantanon |
Depnon |
mianserin a |
(+-)-Athymil |
Spectrum_001810 |
Prestwick0_000099 |
Prestwick1_000099 |
Prestwick2_000099 |
Prestwick3_000099 |
Spectrum2_001203 |
Spectrum3_001836 |
Spectrum4_001260 |
Spectrum5_001772 |
Biomol-NT_000135 |
Lopac0_000744 |
Oprea1_703627 |
SCHEMBL18020 |
BSPBio_000058 |
BSPBio_003511 |
GTPL135 |
KBioGR_001820 |
KBioSS_002303 |
DivK1c_000844 |
SPBio_000986 |
SPBio_001997 |
BPBio1_000064 |
BPBio1_000331 |
DTXSID6023317 |
KBio1_000844 |
KBio2_002301 |
KBio2_004869 |
KBio2_007437 |
KBio3_003016 |
NINDS_000844 |
HMS2089A04 |
HY-B0188 |
Tox21_110191 |
AC-631 |
BDBM50222218 |
PDSP1_001532 |
PDSP2_001516 |
AKOS005216268 |
Tox21_110191_1 |
CCG-204829 |
CS-2078 |
DB06148 |
SDCCGSBI-0050722.P004 |
IDI1_000844 |
NCGC00015656-04 |
NCGC00015656-05 |
NCGC00015656-08 |
NCGC00015656-09 |
NCGC00015656-10 |
NCGC00015656-12 |
NCGC00015656-23 |
NCGC00024926-03 |
NCGC00024926-04 |
5-methyl-2,5-diazatetracyclo13.4.0.0^{2,7}.0^{8,13}nonadeca-1(15),8(13),9,11,16,18-hexaene |
J16.389I |
SBI-0050722.P003 |
AM20041174 |
FT-0697022 |
X5019 |
D08216 |
L000736 |
Q416701 |
BRD-A19661776-001-01-5 |
BRD-A19661776-003-05-2 |
BRD-A19661776-003-16-9 |
2-Methyl-1,2,3,4,10,14b-hexahydrodibenzoc,fpyrazino1,2-aazepine # |
5-methyl-2,5-diazatetracyclo13.4.0.02,7.08,13nonadeca-1(19),8,10,12,15,17-hexaene |
5-methyl-2,5-diazatetracyclo13.4.0.0^{2,7}.0^{8,13}nonadeca-1(19),8,10,12,15,17-hexaene |
Experimental Data
mianserin
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Drosophila melanogaster | 200 | umol/L | 47.16 | 46.4 | -1.61 | NS | MALES | 33008901 | Inactive | ||||
| Caenorhabditis elegans | 50 | umol/L | 38 | Unclear | ok345 | 18033297 | |||||||
| Caenorhabditis elegans | 50 | umol/L | 3 | Unclear | ad1774 | 18033297 | |||||||
| Caenorhabditis elegans | 50 | umol/L | 19 | Unclear | pk1357 | 18033297 | |||||||
| Caenorhabditis elegans | 50 | umol/L | 0 | Unclear | mg280 | 18033297 | |||||||
| Caenorhabditis elegans | 50 | umol/L | 60 | Unclear | tm1325 | 18033297 | |||||||
| Caenorhabditis elegans | 50 | umol/L | -2 | Unclear | ok2007 | 18033297 | Inactive | ||||||
| Caenorhabditis elegans | 50 | umol/L | 7 | Unclear | ok512 | 18033297 | |||||||
| Caenorhabditis elegans | 50 | umol/L | 3 | Unclear | e2519 | 18033297 | |||||||
| Drosophila melanogaster | 20 | umol/L | 52.83 | 56 | 6 | S | FEMALES | 33008901 | Active | ||||
| Caenorhabditis elegans | 50 | umol/L | 4 | Unclear | N2 | 18033297 | |||||||
| Caenorhabditis elegans | 50 | umol/L | 19.6 | 28.3 | 46 | S | N2 | 26255886 | Active | ||||
| Caenorhabditis elegans | 50 | umol/L | 2 | Unclear | n3314 | 18033297 | |||||||
| Caenorhabditis elegans | 50 | umol/L | 2 | Unclear | ad1116 | 18033297 | |||||||
| Caenorhabditis elegans | 50 | umol/L | 10 | Unclear | N2 | 18033297 | |||||||
| Caenorhabditis elegans | 50 | umol/L | 11 | Unclear | e1370 | 18033297 | |||||||
| Caenorhabditis elegans | 50 | umol/L | 31 | S | N2 | 18033297 | Active | ||||||
| Caenorhabditis elegans | 50 | umol/L | 25 | Unclear | ok103 | 18033297 | |||||||
| Caenorhabditis elegans | 50 | umol/L | 1 | Unclear | N2 | 18033297 | |||||||
| Caenorhabditis elegans | 50 | umol/L | 14 | Unclear | mu86 | 18033297 |
Experimental Data Visualization
mianserin
Statistics Data
mianserin
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 60 | 2 | 18 | |
| Drosophila melanogaster | 6 | 1 | 2 |
Statistics Data Visualization
mianserin
