Compound Summary
Compound Information
NICARDIPINE HYDROCHLORIDE
Compound Name: | NICARDIPINE HYDROCHLORIDE |
Compound CID: | 41114 |
Synonyms: | NICARDIPINE HYDROCHLORIDE 54527-84-3 Nicardipine HCl Cardene Perdipine More... |
Iupac Name: | 5-O-[2-[benzyl(methyl)amino]ethyl] 3-O-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate;hydrochloride |
InChI: | InChI=1S/C26H29N3O6.ClH/c1-17-22(25(30)34-4)24(20-11-8-12-21(15-20)29(32)33)23(18(2)27-17)26(31)35-14-13-28(3)16-19-9-6-5-7-10-19;/h5-12,15,24,27H,13-14,16H2,1-4H3;1H |
InChIKey: | AIKVCUNQWYTVTO-UHFFFAOYSA-N |
Canonical Smiles: | CC1=C(C(C(=C(N1)C)C(=O)OCCN(C)CC2=CC=CC=C2)C3=CC(=CC=C3)[N+](=O)[O-])C(=O)OC.Cl |
Isomeric Smiles: | CC1=C(C(C(=C(N1)C)C(=O)OCCN(C)CC2=CC=CC=C2)C3=CC(=CC=C3)[N+](=O)[O-])C(=O)OC.Cl |
Molecular Weight: | 516 |
Molecular Formula: | C26H30ClN3O6 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
NICARDIPINE HYDROCHLORIDE
Molecular Weight: | 516 |
Molecular Formula: | C26H30ClN3O6 |
Hydrogen Bond Donor Count: | 2 |
Hydrogen Bond Acceptor Count: | 8 |
Rotatable Bond Count: | 10 |
Heavy Atom Count: | 36 |
Complexity: | 856 |
Synonyms
NICARDIPINE HYDROCHLORIDE
| NICARDIPINE HYDROCHLORIDE | NICARDIPINE HYDROCHLORIDE |
|---|---|
NICARDIPINE HYDROCHLORIDE |
54527-84-3 |
Nicardipine HCl |
Cardene |
Perdipine |
Nicodel |
Loxen |
YC-93 |
Nicardipine (Hydrochloride) |
Dagan |
YC-93 hydrochloride |
RS-69216 |
RS-69216-XX-07-0 |
MLS000069782 |
2-(Benzylmethylamino)ethyl methyl 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylatemonohydrochloride |
MFCD00057327 |
3-{2-benzyl(methyl)aminoethyl} 5-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate hydrochloride |
Angioglebil |
Bionicard |
Nicardil |
Perdipina |
SMR000058487 |
Lincil |
Dafil |
Cardene (TN) |
Cardene SR |
3-(2-(benzyl(methyl)amino)ethyl) 5-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate hydrochloride |
5-O-2-benzyl(methyl)aminoethyl 3-O-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate;hydrochloride |
YC 93 |
SR-01000075333 |
EINECS 259-198-4 |
Nicardipine hydrochloride USAN:JAN |
Nerdipine |
Perpidine |
nicardipine; |
CCRIS 8508 |
Prestwick_590 |
EINECS 274-007-4 |
69441-18-5 |
Opera_ID_357 |
Cardene In 4.8% Dextrose In Plastic Container |
Cardene In 5.0% Dextrose In Plastic Container |
CAS-54527-84-3 |
DSSTox_CID_26992 |
DSSTox_RID_82040 |
DSSTox_GSID_46992 |
SCHEMBL41845 |
2-(Benzylmethylamino)ethyl methyl 1,4-dihydro-2,6-dimethyl-4-(m-nitrophenyl)-3,5-pyridinedicarboxylate monohydrochloride |
MLS001146898 |
MLS002153279 |
MLS002153794 |
Nicardipine hydrochloride,(S) |
SPECTRUM1501135 |
CHEBI:7551 |
Cardene In 0.83% Sodium Chloride In Plastic Container |
Cardene In 0.86% Sodium Chloride In Plastic Container |
CHEMBL1200326 |
CHEMBL3199626 |
DTXSID9046992 |
HMS1569M07 |
HMS1921H21 |
Pharmakon1600-01501135 |
BCP05610 |
EBD48801 |
Tox21_301832 |
Tox21_500809 |
CCG-39033 |
HY-12515A |
NSC757855 |
s4181 |
TN-901 |
AKOS015994734 |
BCP9000988 |
CS-3684 |
KS-1276 |
LP00809 |
NC00578 |
NSC 757855 |
NSC-757855 |
RS-69216-XX-07-O |
RS-69216XX07-0 |
Nicardipine hydrochloride (JP17/USAN) |
NCGC00094142-01 |
NCGC00094142-02 |
NCGC00094142-03 |
NCGC00094142-04 |
NCGC00094142-05 |
NCGC00256289-01 |
NCGC00261494-01 |
1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)methyl-2-methyl(phenylmethyl)amino-3,5-pyridinedicarboxylic acid ethyl ester hydrochloride |
2-(Benzyl(methyl)amino)ethyl methyl 1,4-dihydro-2,6-dimethyl-4-(m-nitrophenyl)pyridine-3,5-dicarboxylate hydrochloride |
3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, methyl 2-(methyl(phenylmethyl)amino)ethyl ester, monohydrochloride |
3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(m-nitrophenyl)-, 2-(benzylmethylamino)ethyl methyl ester, monohydrochloride |
Nicardipine hydrochloride, powder, >=98% |
DB-052598 |
EU-0100809 |
FT-0630671 |
N0635 |
SW196762-3 |
D00617 |
D91754 |
N 7510 |
527N843 |
A830225 |
SR-01000075333-1 |
SR-01000075333-5 |
W-105615 |
Q27281986 |
12-(7-NITROBENZOFURAZAN-4-YLAMINO)DODECANOICACID |
Nicardipine hydrochloride, European Pharmacopoeia (EP) Reference Standard |
Nicardipine for system suitability, European Pharmacopoeia (EP) Reference Standard |
Nicardipine hydrochloride, United States Pharmacopeia (USP) Reference Standard |
1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid methyl 2-methyl(phenylmethyl)aminoethyl ester hydrochloride |
2-(N-benzyl-N-methylamino)ethyl methyl 2,6-dimethyl-4-(m-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate hydrochloride |
3,5-pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 3-methyl 5-2-methyl(phenylmethyl)aminoethyl ester, hydrochloride (1:1) |
O5-2-benzyl(methyl)aminoethyl O3-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate hydrochloride;Nicardipine HCl |
Experimental Data
NICARDIPINE HYDROCHLORIDE
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33 | umol/L | 23 | S | N2 | 24134630 | Active | ||||||
| Caenorhabditis elegans | 33 | umol/L | 23 | S | N2 | 33683565 | Active |
Experimental Data Visualization
NICARDIPINE HYDROCHLORIDE
Statistics Data
NICARDIPINE HYDROCHLORIDE
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 23 | 2 | 2 |
Statistics Data Visualization
NICARDIPINE HYDROCHLORIDE
