Compound Summary
Compound Information
VUF 5574
Compound Name: | VUF 5574 |
Compound CID: | 4046493 |
Synonyms: | VUF 5574 280570-45-8 VUF5574 VUF-5574 CHEMBL70880 More... |
Iupac Name: | 1-(2-methoxyphenyl)-3-(2-pyridin-3-ylquinazolin-4-yl)urea |
InChI: | InChI=1S/C21H17N5O2/c1-28-18-11-5-4-10-17(18)24-21(27)26-20-15-8-2-3-9-16(15)23-19(25-20)14-7-6-12-22-13-14/h2-13H,1H3,(H2,23,24,25,26,27) |
InChIKey: | YRAFEJSZTVWUMD-UHFFFAOYSA-N |
Canonical Smiles: | COC1=CC=CC=C1NC(=O)NC2=NC(=NC3=CC=CC=C32)C4=CN=CC=C4 |
Isomeric Smiles: | COC1=CC=CC=C1NC(=O)NC2=NC(=NC3=CC=CC=C32)C4=CN=CC=C4 |
Molecular Weight: | 371.4 |
Molecular Formula: | C21H17N5O2 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
VUF 5574
Molecular Weight: | 371.4 |
Molecular Formula: | C21H17N5O2 |
Hydrogen Bond Donor Count: | 2 |
Hydrogen Bond Acceptor Count: | 5 |
Rotatable Bond Count: | 4 |
Heavy Atom Count: | 28 |
Complexity: | 519 |
Synonyms
VUF 5574
| VUF 5574 | VUF 5574 |
|---|---|
VUF 5574 |
280570-45-8 |
VUF5574 |
VUF-5574 |
CHEMBL70880 |
3-(2-methoxyphenyl)-1-(2-pyridin-3-ylquinazolin-4-yl)urea |
1-(2-Methoxyphenyl)-3-(2-(pyridin-3-yl)quinazolin-4-yl)urea |
NCGC00016084-01 |
Lopac-V-5888 |
Lopac0_001247 |
SCHEMBL935642 |
GTPL3280 |
DTXSID00398737 |
1-(2-methoxyphenyl)-3-(2-pyridin-3-ylquinazolin-4-yl)urea |
ZINC602599 |
BDBM50088475 |
AKOS000749577 |
CCG-205321 |
MCULE-2693307443 |
NCGC00016084-02 |
NCGC00016084-03 |
NCGC00016084-04 |
NCGC00016084-05 |
NCGC00094488-01 |
NCGC00094488-02 |
NCGC00094488-03 |
NCGC00094488-04 |
B6703 |
EU-0101247 |
EC-000.2112 |
V 5888 |
SR-01000076193 |
J-016958 |
SR-01000076193-1 |
Q27089203 |
1-(2-Methoxy-phenyl)-3-(2-pyridin-3-yl-quinazolin-4-yl)-urea |
N-(2-Methoxyphenyl)-N-2-(3-pyridinyl)-4-quinazolinyl-urea" |
N-(2-Methoxyphenyl)-N-2-(3-pyrindinyl)-4-quinazolinyl-urea" |
Experimental Data
VUF 5574
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33 | umol/L | -16 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
VUF 5574
Statistics Data
VUF 5574
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | -16 | 1 | 1 |
Statistics Data Visualization
VUF 5574
