Compound Summary
Compound Information
methyldopa
Compound Name: | methyldopa |
Compound CID: | 38853 |
Synonyms: | methyldopa 555-30-6 Alphamethyldopa Aldomet Dopamet More... |
Iupac Name: | (2S)-2-amino-3-(3,4-dihydroxyphenyl)-2-methylpropanoic acid |
InChI: | InChI=1S/C10H13NO4/c1-10(11,9(14)15)5-6-2-3-7(12)8(13)4-6/h2-4,12-13H,5,11H2,1H3,(H,14,15)/t10-/m0/s1 |
InChIKey: | CJCSPKMFHVPWAR-JTQLQIEISA-N |
Canonical Smiles: | CC(CC1=CC(=C(C=C1)O)O)(C(=O)O)N |
Isomeric Smiles: | C[C@](CC1=CC(=C(C=C1)O)O)(C(=O)O)N |
Molecular Weight: | 211.21 |
Molecular Formula: | C10H13NO4 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
methyldopa
Molecular Weight: | 211.21 |
Molecular Formula: | C10H13NO4 |
Hydrogen Bond Donor Count: | 4 |
Hydrogen Bond Acceptor Count: | 5 |
Rotatable Bond Count: | 3 |
Heavy Atom Count: | 15 |
Complexity: | 246 |
Synonyms
methyldopa
| methyldopa | methyldopa |
|---|---|
methyldopa |
555-30-6 |
Alphamethyldopa |
Aldomet |
Dopamet |
Alpha medopa |
l-alpha-Methyldopa |
Methyl dopa |
alpha-Methyl dopa |
Baypresol |
Hyperpax |
Presolisin |
Sedometil |
Medomet |
L-(-)-alpha-Methyldopa |
Methyldopa anhydrous |
alpha-Methyldopa |
3-(3,4-DIHYDROXYPHENYL)-2-METHYL-L-ALANINE |
Methyl-L-dopa |
L-Methyl Dopa |
Methyldopum |
Metildopa |
(S)-(-)-alpha-Methyldopa |
L-(alpha-Md) |
3-Hydroxy-alpha-methyl-L-tyrosine |
L-alpha-Methyl DOPA |
Sembrina |
Dopegyt |
alpha-Methyl-L-dopa |
Dopamethyperpax |
Aldometil |
Grospisk |
Medopren |
Methoplain |
Presinol |
Becanta |
Dopatec |
Hypolag |
Medopa |
Medopal |
alpha-Methyldopa (VAN) |
Aldoril |
alpha-Methyldihydroxyphenylalanine |
(S)-2-Amino-3-(3,4-dihydroxyphenyl)-2-methylpropanoic acid |
alpha-Methyl-L-3,4-dihydroxyphenylalanine |
L-alpha-Methyl-3,4-dihydroxyphenylalanine |
L-Methyldopa |
l-3-(3,4-Dihydroxyphenyl)-2-methylalanine |
Aldoril D30 |
Aldoril D50 |
Methyldopa (L,-) |
Bayer 1440 L |
levo-3-(3,4-Dihydroxyphenyl)-2-methylalanine |
AMD |
C10H13NO4 |
L-(-)-3-(3,4-Dihydroxyphenyl)-2-methylalanine |
alpha-Methyl-beta-(3,4-dihydroxyphenyl)-L-alanine |
(2S)-2-amino-3-(3,4-dihydroxyphenyl)-2-methylpropanoic acid |
L(-)-beta-(3,4-Dihydroxyphenyl)-alpha-methylalanine |
L-(-)-alpha-Methyl-beta-(3,4-dihydroxyphenyl)alanine |
UNII-M4R0H12F6M |
Methyldopa (INN) |
Methyldopa INN |
L-2-Amino-2-methyl-3-(3,4-dihydroxyphenyl)propionic acid |
MK-351;Methyldopa |
CHEBI:61058 |
41372-08-1 |
alpha-Methyldopa sesquihydrate |
Aldomet (TN) |
Dopegit |
MK-351 |
METHYLDOPA SESQUIHYDRATE |
MLS000028644 |
M4R0H12F6M |
Apo-Methyldopa |
Nu-Medopa |
Methyldopa hydrate |
Novomedopa |
SMR000059170 |
Methyldopum INN-Latin |
Metildopa INN-Spanish |
Methyldopa (anhydrous) |
3-Hydroxy-.alpha.-methyl-L-tyrosine |
L-Tyrosine, 3-hydroxy-alpha-methyl- |
CCRIS 4671 |
HSDB 218 |
SR-01000597712 |
EINECS 209-089-2 |
Methyldopa (Levorotatory) |
NSC 169916 |
Medoba |
l-a-methyldopa |
a-methyl dopa |
NSC169916 |
a-methyl-l-dopa |
3,4-Dihydroxy-2-methylphenylalanine # |
NSC-169916 |
Anhydrous methyldopa |
CAS-555-30-6 |
Prestwick_732 |
(-)-a-methyldopa |
a-methyldopa (van) |
Methyldopa (Aldomet) |
88620-56-8 |
Alanine, 3-(3,4-dihydroxyphenyl)-2-methyl-, L-(-)- |
Methyldopa 250 Tab |
(-)-alpha-methyldopa |
L-(-)--Methyldopa |
L(-)-a-methylalanine |
L-(-)-a-Methyldopa |
Spectrum_000937 |
Tocris-0584 |
MK-351; Methyldopa |
Nu-Medopa Tab 125mg |
Nu-Medopa Tab 250mg |
Nu-Medopa Tab 500mg |
L-(-)-?-Methyldopa |
(-)-3-(3,4-Dihydroxyphenyl)-2-Methyl-L-Alanine Sesqui-Hydrate |
Novo-Medopa Tab 125mg |
Novo-Medopa Tab 250mg |
Novo-Medopa Tab 500mg |
Prestwick0_000326 |
Prestwick1_000326 |
Prestwick2_000326 |
Prestwick3_000326 |
Spectrum2_001068 |
Spectrum3_000501 |
Spectrum4_000054 |
Spectrum5_001295 |
(s)-(-)-a-methyldopa |
L(-)-alpha-methylalanine |
DSSTox_CID_3295 |
CHEMBL459 |
Epitope ID:146097 |
L-(-)- alpha-Methyldopa |
Apo Methyldopa Tab 125mg |
Apo Methyldopa Tab 250mg |
Apo Methyldopa Tab 500mg |
DSSTox_RID_76962 |
DSSTox_GSID_23295 |
L-(a-MD) |
Lopac0_000853 |
SCHEMBL34003 |
BSPBio_000331 |
BSPBio_002021 |
KBioGR_000547 |
KBioSS_001417 |
cid_38853 |
MLS006011978 |
BAYER-1440L |
BIDD:GT0620 |
DivK1c_000142 |
Methyldopa 125 Tab 125mg |
Methyldopa 500 Tab 500mg |
SPECTRUM1500403 |
SPBio_001056 |
SPBio_002252 |
alpha-Methyl-dopa sesquihydrate |
BPBio1_000365 |
GTPL5217 |
DTXSID5023295 |
BDBM48449 |
HMS500H04 |
KBio1_000142 |
KBio2_001417 |
KBio2_003985 |
KBio2_006553 |
KBio3_001521 |
ZINC20255 |
3-(3,4-Dihydroxyphenyl)-2-methyl-L-alanine sesquihydrate |
5-amino-2-fluorophenylboronicacid |
NINDS_000142 |
HMS1569A13 |
HMS1920N09 |
HMS2090B11 |
HMS2091F04 |
HMS2096A13 |
HMS2235N11 |
HMS3262L07 |
HMS3372J14 |
HMS3411G18 |
HMS3675G18 |
HMS3713A13 |
HMS3887I15 |
Pharmakon1600-01500403 |
L-(-)-a-methyl-a-methyl-Aldomin |
HY-B0225 |
Tox21_202610 |
Tox21_500853 |
CCG-40120 |
CM0081 |
DL-443 |
MFCD00004186 |
NSC760080 |
s1642 |
Tyrosine, 3-hydroxy-.alpha.-methyl- |
a-Methyl-L-3,4-dihydroxyphenylalanine |
AKOS015960582 |
AC-8431 |
DB00968 |
J9.247I |
KS-1424 |
LP00853 |
MCULE-8885874119 |
NSC-760080 |
SDCCGSBI-0050829.P002 |
IDI1_000142 |
NCGC00024667-01 |
NCGC00024667-02 |
NCGC00024667-03 |
NCGC00024667-05 |
NCGC00024667-06 |
NCGC00024667-07 |
NCGC00024667-08 |
NCGC00024667-09 |
NCGC00024667-10 |
NCGC00024667-11 |
NCGC00024667-13 |
NCGC00024667-21 |
NCGC00260158-01 |
NCGC00261538-01 |
AC-11671 |
AS-13052 |
L-(-)-alpha-methyl-alpha-methyl-Aldomin |
L-a-Methyl-(3, 4-dihydroxyphenyl)alanine |
D1817 |
EU-0100853 |
3-(3,4-Dihydroxyphenyl)-?-methyl-L-alanine |
L-alpha-Methyl-(3, 4-dihydroxyphenyl)alanine |
C07194 |
D08205 |
D82313 |
AB00052043_09 |
AB01275508-01 |
AB01275508_02 |
3-(3,4-Dihydroxyphenyl)-alpha-methyl-L-a lanine |
L-Tyrosine, 3-hydroxy-alpha-methyl-, homopolymer |
Q412621 |
L-(-)-3-(3,4-dihydroxyphenyl)-2-methyl-Alanine |
Q-201392 |
SR-01000597712-1 |
SR-01000597712-3 |
W-105555 |
3,4-dihydroxy-2-methylphenylalanine (ACD/Name 4.0) |
Z1565440340 |
Methyldopa, European Pharmacopoeia (EP) Reference Standard |
UNII-33TD13T99R component CJCSPKMFHVPWAR-JTQLQIEISA-N |
(2S)-2-amino-3-(3,4-dihydroxyphenyl)-2-methyl-propanoic acid |
(2S)-2-azaniumyl-3-(3,4-dihydroxyphenyl)-2-methylpropanoate |
Methyldopa, United States Pharmacopeia (USP) Reference Standard |
Methyldopa for system suitability, European Pharmacopoeia (EP) Reference Standard |
27289-76-5 |
L-(-)-AfAEA centa notA inverted exclamation markAfasAA|AfAEAdaggeratrade mark?-Methyldopa" |
Experimental Data
methyldopa
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33 | umol/L | 10 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
methyldopa
Statistics Data
methyldopa
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 10 | 1 | 1 |
Statistics Data Visualization
methyldopa
