Compound Summary
Compound Information
beta-Lapachone
Compound Name: | beta-Lapachone |
Compound CID: | 3885 |
Synonyms: | beta-Lapachone 4707-32-8 lapachone 2,2-Dimethyl-3,4-dihydro-2H-benzohchromene-5,6-dione Lapachone, beta- More... |
Iupac Name: | 2,2-dimethyl-3,4-dihydrobenzo[h]chromene-5,6-dione |
InChI: | InChI=1S/C15H14O3/c1-15(2)8-7-11-13(17)12(16)9-5-3-4-6-10(9)14(11)18-15/h3-6H,7-8H2,1-2H3 |
InChIKey: | QZPQTZZNNJUOLS-UHFFFAOYSA-N |
Canonical Smiles: | CC1(CCC2=C(O1)C3=CC=CC=C3C(=O)C2=O)C |
Isomeric Smiles: | CC1(CCC2=C(O1)C3=CC=CC=C3C(=O)C2=O)C |
Molecular Weight: | 242.27 |
Molecular Formula: | C15H14O3 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
beta-Lapachone
Molecular Weight: | 242.27 |
Molecular Formula: | C15H14O3 |
Hydrogen Bond Donor Count: | 0 |
Hydrogen Bond Acceptor Count: | 3 |
Rotatable Bond Count: | 0 |
Heavy Atom Count: | 18 |
Complexity: | 445 |
Synonyms
beta-Lapachone
| beta-Lapachone | beta-Lapachone |
|---|---|
beta-Lapachone |
4707-32-8 |
lapachone |
2,2-Dimethyl-3,4-dihydro-2H-benzohchromene-5,6-dione |
Lapachone, beta- |
ARQ 501 |
ARQ-501 |
.beta.-Lapachone |
3,4-Dihydro-2,2-dimethyl-2H-naphtho1,2-Bpyran-5,6-dione |
UNII-6N4FA2QQ6A |
2,2-dimethyl-3,4-dihydrobenzohchromene-5,6-dione |
NSC-26326 |
ARQ-501 (beta lapachone) |
3,4-Dihydro-2,2-dimethyl-2H-naphtho(1,2-b)pyran-5,6-dione |
2H-Naphtho1,2-bpyran-5,6-dione, 3,4-dihydro-2,2-dimethyl- |
3,4-Dihydro-2,2-dimethyl-2H-naphthol1,2-bpyran-5,6-dione |
6N4FA2QQ6A |
CHEBI:10429 |
NSC26326 |
NSC629749 |
ARQ-501;NSC-26326 |
NSC-629749 |
LAPACHONE, BETA |
2H-Naphtho(1,2-b)pyran-5,6-dione, 3,4-dihydro-2,2-dimethyl- |
NSC 26326 |
SL 11001 |
SR-01000075957 |
NSC 629749 |
BRN 0181499 |
Beta lapachone |
b-Lapachone |
beta-lap |
Lapachone, .beta. |
MB12066 |
beta-Lapachone (90%) |
Lopac-L-2037 |
Lopac0_000717 |
BSPBio_001306 |
KBioGR_000026 |
KBioSS_000026 |
2005rm01ch01 |
5-17-11-00459 (Beilstein Handbook Reference) |
MLS006011731 |
R115 (Reactive Blue 2) |
CHEMBL15192 |
SCHEMBL107042 |
ARQ501 |
BCBcMAP01_000055 |
BDBM81348 |
KBio2_000026 |
KBio2_002594 |
KBio2_005162 |
KBio3_000051 |
KBio3_000052 |
DTXSID90197019 |
beta-Lapachone, >=98% (TLC) |
Bio2_000026 |
Bio2_000506 |
HMS1361B08 |
HMS1791B08 |
HMS1989B08 |
HMS3262O15 |
HMS3402B08 |
HMS3653O04 |
HMS3866G13 |
BCP09779 |
EX-A3011 |
ZINC1531790 |
Tox21_500717 |
2265AH |
CCG-36362 |
HSCI1_000182 |
MFCD01712233 |
NSC813862 |
s7261 |
(c)micro-Lapachone pound>>ARQ 501 |
AKOS005266281 |
AC-8965 |
ACN-025762 |
AT-8531 |
CS-3680 |
DB11948 |
LP00717 |
NSC-813862 |
SDCCGSBI-0050695.P003 |
VZ25538 |
IDI1_033776 |
QTL1_000048 |
beta-Lapachone (ARQ-501, CO-501) |
NCGC00015598-01 |
NCGC00015598-02 |
NCGC00015598-03 |
NCGC00015598-04 |
NCGC00015598-05 |
NCGC00015598-06 |
NCGC00015598-07 |
NCGC00015598-08 |
NCGC00015598-17 |
NCGC00094066-01 |
NCGC00094066-02 |
NCGC00094066-03 |
NCGC00094066-04 |
NCGC00094066-05 |
NCGC00261402-01 |
AS-70326 |
HY-13555 |
MB-12066 |
NCI60_009665 |
QC-11644 |
SL-11001 |
SMR001456339 |
DB-021896 |
EU-0100717 |
FT-0635405 |
SW219806-1 |
A13059 |
C75251 |
A827146 |
SR-01000075957-1 |
SR-01000075957-5 |
2H-Naphtho1,6-dione, 3,4-dihydro-2,2-dimethyl- |
Q27089386 |
2,2-Dimethyl-3,4-dihydro-2H-benzohchromene-5,6-dione # |
3,4-Dihydro-2,2-dimethyl-2H-naphthol1,2-bpyran-5,6dione |
2,2-dimethyl-2H,3H,4H,5H,6H-naphtho1,2-bpyran-5,6-dione |
AfAEA centa notA inverted exclamation markAfasAA|AfAEAdaggeratrade markAfA centA centasA notA em leaderA inverted exclamation mark-Lapachone" |
Experimental Data
beta-Lapachone
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33 | umol/L | -8 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
beta-Lapachone
Statistics Data
beta-Lapachone
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | -8 | 1 | 1 |
Statistics Data Visualization
beta-Lapachone
