Compound Summary
Compound Information
JL-18
Compound Name: | JL-18 |
Compound CID: | 3802 |
Synonyms: | JL-18 JL 18 147395-65-1 NCGC00094013-01 8-methyl-6-(4-methylpiperazin-1-yl)-11h-pyrido2,3-b1,4benzodiazepine More... |
Iupac Name: | 8-methyl-6-(4-methylpiperazin-1-yl)-11H-pyrido[2,3-b][1,4]benzodiazepine |
InChI: | InChI=1S/C18H21N5/c1-13-5-6-15-14(12-13)18(23-10-8-22(2)9-11-23)21-16-4-3-7-19-17(16)20-15/h3-7,12H,8-11H2,1-2H3,(H,19,20) |
InChIKey: | MMCMKWDIEUZMQB-UHFFFAOYSA-N |
Canonical Smiles: | CC1=CC2=C(C=C1)NC3=C(C=CC=N3)N=C2N4CCN(CC4)C |
Isomeric Smiles: | CC1=CC2=C(C=C1)NC3=C(C=CC=N3)N=C2N4CCN(CC4)C |
Molecular Weight: | 307.4 |
Molecular Formula: | C18H21N5 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
JL-18
Molecular Weight: | 307.4 |
Molecular Formula: | C18H21N5 |
Hydrogen Bond Donor Count: | 1 |
Hydrogen Bond Acceptor Count: | 4 |
Rotatable Bond Count: | 1 |
Heavy Atom Count: | 23 |
Complexity: | 443 |
Synonyms
JL-18
| JL-18 | JL-18 |
|---|---|
JL-18 |
JL 18 |
147395-65-1 |
NCGC00094013-01 |
8-methyl-6-(4-methylpiperazin-1-yl)-11h-pyrido2,3-b1,4benzodiazepine |
8-Methyl-6-(4-methyl-1-piperazinyl)-11H-pyrido(2,3-b)(1,4)benzodiazepine |
CHEMBL63329 |
ACMC-20dd8i |
Lopac-J-102 |
Lopac0_000646 |
SCHEMBL4358144 |
DTXSID70163696 |
HMS3262A13 |
Tox21_500646 |
BDBM50040245 |
11H-Pyrido2,3-b1,4benzodiazepine,8-methyl-6-(4-methyl-1-piperazinyl)- |
CCG-204733 |
LP00646 |
SDCCGSBI-0050626.P002 |
NCGC00015574-01 |
NCGC00015574-02 |
NCGC00015574-03 |
NCGC00015574-04 |
NCGC00094013-02 |
NCGC00261331-01 |
EU-0100646 |
J-102 |
SR-01000075386 |
SR-01000075386-1 |
8-Methyl-6-(4-methyl-1-piperazinyl)-11H-pyrido2,3-b1,4benzeodiazepine |
8-Methyl-6-(4-methyl-piperazin-1-yl)-11H-benzoepyrido3,2-b1,4diazepine |
Experimental Data
JL-18
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33 | umol/L | 6 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
JL-18
Statistics Data
JL-18
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 6 | 1 | 1 |
Statistics Data Visualization
JL-18
