Compound Summary
Compound Information
Buspirone hydrochloride
Compound Name: | Buspirone hydrochloride |
Compound CID: | 36431 |
Synonyms: | Buspirone hydrochloride 33386-08-2 Buspar Buspirone HCL Narol More... |
Iupac Name: | 8-[4-(4-pyrimidin-2-ylpiperazin-1-yl)butyl]-8-azaspiro[4.5]decane-7,9-dione;hydrochloride |
InChI: | InChI=1S/C21H31N5O2.ClH/c27-18-16-21(6-1-2-7-21)17-19(28)26(18)11-4-3-10-24-12-14-25(15-13-24)20-22-8-5-9-23-20;/h5,8-9H,1-4,6-7,10-17H2;1H |
InChIKey: | RICLFGYGYQXUFH-UHFFFAOYSA-N |
Canonical Smiles: | C1CCC2(C1)CC(=O)N(C(=O)C2)CCCCN3CCN(CC3)C4=NC=CC=N4.Cl |
Isomeric Smiles: | C1CCC2(C1)CC(=O)N(C(=O)C2)CCCCN3CCN(CC3)C4=NC=CC=N4.Cl |
Molecular Weight: | 422 |
Molecular Formula: | C21H32ClN5O2 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
Buspirone hydrochloride
Molecular Weight: | 422 |
Molecular Formula: | C21H32ClN5O2 |
Hydrogen Bond Donor Count: | 1 |
Hydrogen Bond Acceptor Count: | 6 |
Rotatable Bond Count: | 6 |
Heavy Atom Count: | 29 |
Complexity: | 529 |
Synonyms
Buspirone hydrochloride
| Buspirone hydrochloride | Buspirone hydrochloride |
|---|---|
Buspirone hydrochloride |
33386-08-2 |
Buspar |
Buspirone HCL |
Narol |
Buspimen |
Buspirone (hydrochloride) |
8-(4-(4-(pyrimidin-2-yl)piperazin-1-yl)butyl)-8-azaspiro4.5decane-7,9-dione hydrochloride |
UNII-207LT9J9OC |
MJ 9022-1 |
C21H32ClN5O2 |
MLS000069796 |
207LT9J9OC |
CHEBI:3224 |
Bespar |
Apo-Buspirone |
MFCD00078569 |
N-(4-(4-(2-Pyrimidinyl)-1-piperazinyl)butyl)-1,1-cyclopentanediacetamide monohydrochloride |
N-4-4-(2-Pyrimidinyl)-1-piperazinylbutyl-8-azaspiro4.5decane-7,9-dione hydrochloride |
MJ-9022-1 |
Ansitec |
Anxinil |
Anxiolan |
Busirone |
Buspinol |
Censpar |
Effiplen |
Establix |
Kallmiren |
Lucelan |
Mabuson |
Normaton |
SMR000058186 |
Spamilan |
Barpil |
Itagil |
Nerbet |
Sburol |
Travin |
Tutran |
Biron |
Relac |
33386-08-2 (HCl) |
8-4-(4-pyrimidin-2-ylpiperazin-1-yl)butyl-8-azaspiro4.5decane-7,9-dione;hydrochloride |
8-4-(4-pyrimidin-2-ylpiperazin-1-yl)butyl-8-azaspiro4.5decane-7,9-dione hydrochloride |
8-{4-4-(pyrimidin-2-yl)piperazin-1-ylbutyl}-8-azaspiro4.5decane-7,9-dione hydrochloride |
SR-01000075541 |
EINECS 251-489-4 |
C21H31N5O2.HCl |
Prestwick_711 |
Buspirone hydrochloride USAN:USP |
Buspar (TN) |
Opera_ID_707 |
1,1-Cyclopentanediacetimide, N-(4-(4-(2-pyrimidinyl)-1-piperazinyl)butyl)-, hydrochloride |
8-(4-(4-(2-Pyrimidinyl)-1-piperazinyl)butyl)-8-azaspiro(4.5)decane-7,9-dione hydrochloride |
SCHEMBL41495 |
MLS001076085 |
MLS002548862 |
Buspirone hydrochloride (USP) |
APD405 |
Buspirone hydrochloride solution |
CHEMBL1200399 |
DTXSID1037193 |
APD-405 |
HMS1569I19 |
HMS3750O03 |
Pharmakon1600-02300173 |
APC-6002 |
APC-6003 |
BCP28463 |
HY-B1115 |
Tox21_500223 |
NSC751138 |
NSC759571 |
s4256 |
AKOS015962019 |
AC-1905 |
CCG-213652 |
CS-4714 |
H05B847 |
KS-5163 |
LP00223 |
MCULE-3504513666 |
NC00673 |
NSC 751138 |
NSC 759571 |
NSC-751138 |
NSC-759571 |
VA10444 |
NCGC00093692-01 |
NCGC00093692-02 |
NCGC00260908-01 |
8-(4-(4-(2-Pyrimidinyl)-1-piperazinyl)butyl)-8-azaspiro(4.5)decane-7,9-dione monohydrochloride |
8-Azaspiro(4,5)decane-7,9-dione, 8-(4-(4-(2-pyrimidinyl)-1-piperazinyl)butyl)-, monohydrochloride |
EU-0100223 |
ST51014924 |
SW155073-5 |
B 7148 |
D00702 |
D96810 |
J10144 |
Q-200768 |
SR-01000075541-1 |
SR-01000075541-3 |
SR-01000075541-7 |
Q27105997 |
Buspirone Hydrochloride 1.0 mg/ml in Methanol (as free base) |
Buspirone hydrochloride, European Pharmacopoeia (EP) Reference Standard |
Buspirone hydrochloride, United States Pharmacopeia (USP) Reference Standard |
8-4-(4-pyrimidin-2-ylpiperazinyl)butyl-8-azaspiro4.5decane-7,9-dione, chlo ride |
8-Azaspiro4.5decane-7, 8-4-4-(2-pyrimidinyl)-1-piperazinylbutyl-, monohydrochloride |
Buspirone for system suitability, European Pharmacopoeia (EP) Reference Standard |
Buspirone hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material |
1-4-(7,9-dioxo-8-azaspiro4.5decan-8-yl)butyl-4-(pyrimidin-2-yl)piperazin-1-ium chloride |
8-4-4-(2-Pyrimidinyl)-1-pipirazin ylbutyl-8-azaspiro4,5decane-7,9-dione hydrochloride |
8-4-4-(2-Pyrimidinyl)-1-pipirazinylbutyl-8-azaspiro4,5decane-7,9-dione hydrochloride |
8-4-4-(pyrimidine-2-yl)-piperazine-1-yl-butyl-8-aza-spiro4.5decane-7,9-dione hydrochloride |
Buspirone HCl pound>>MJ 9022 1 pound>> MJ-9022-1 pound>>MJ90221 pound>>MJ9022 1 pound>>MJ9022-1 |
Buspirone hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material |
Experimental Data
Buspirone hydrochloride
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 33 | umol/L | -2 | NS | N2 | 24134630 | Inactive |
Experimental Data Visualization
Buspirone hydrochloride
Statistics Data
Buspirone hydrochloride
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | -2 | 1 | 1 |
Statistics Data Visualization
Buspirone hydrochloride
