Compound Summary
Compound Information
hydralazine
Compound Name: | hydralazine |
Compound CID: | 3637 |
Synonyms: | hydralazine 1-Hydrazinophthalazine 86-54-4 Hydralazin 1-Hydrazinylphthalazine More... |
Iupac Name: | phthalazin-1-ylhydrazine |
InChI: | InChI=1S/C8H8N4/c9-11-8-7-4-2-1-3-6(7)5-10-12-8/h1-5H,9H2,(H,11,12) |
InChIKey: | RPTUSVTUFVMDQK-UHFFFAOYSA-N |
Canonical Smiles: | C1=CC=C2C(=C1)C=NN=C2NN |
Isomeric Smiles: | C1=CC=C2C(=C1)C=NN=C2NN |
Molecular Weight: | 160.18 |
Molecular Formula: | C8H8N4 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
hydralazine
Molecular Weight: | 160.18 |
Molecular Formula: | C8H8N4 |
Hydrogen Bond Donor Count: | 2 |
Hydrogen Bond Acceptor Count: | 4 |
Rotatable Bond Count: | 1 |
Heavy Atom Count: | 12 |
Complexity: | 150 |
Synonyms
hydralazine
| hydralazine | hydralazine |
|---|---|
hydralazine |
1-Hydrazinophthalazine |
86-54-4 |
Hydralazin |
1-Hydrazinylphthalazine |
Hypophthalin |
Hydrazinophthalazine |
Apresoline |
Apresolin |
Apressin |
Idralazina |
phthalazin-1-ylhydrazine |
1(2H)-Phthalazinone, hydrazone |
6-Hydralazine |
Aprezolin |
Hidralazin |
Hidralazina |
Hipoftalin |
Hydrallazine |
1-Phthalazinylhydrazine |
Hydralazinum |
59275-69-3 |
Hydrazone 1(2H)-phthalazinone |
Ciba 5968 |
Apressin (pharmaceutical) |
(E)-1-Hydrazono-1,2-dihydrophthalazine |
BA 5968 |
Phthalazine, 1-hydrazino- |
Praparat 5968 |
(2H)-Phthalazinone hydrazone |
C-5968 |
UNII-26NAK24LS8 |
(1Z)-1(2H)-Phthalazinone hydrazone |
C 5968 |
NSC 126699 |
CHEBI:5775 |
26NAK24LS8 |
Apresolin; Apresoline; Apressin |
C-5068 |
phthalazinylhydrazine |
NSC-126699 |
Idralazina DCIT |
Idralazina Italian |
Hidralazina Spanish |
Hydralazine INN:BAN |
Hydralazinum INN-Latin |
Hidralazina INN-Spanish |
1(2H)-Phthalazinone hydrazone |
Hydralazine (INN) |
Hidral (TN) |
CCRIS 5385 |
NCGC00015501-02 |
CAS-304-20-1 |
EINECS 201-680-3 |
BRN 0132615 |
phthalazone hydrazone |
Hydralazine polistirex |
1-hydrazonophthalazine |
Spectrum_000875 |
Prestwick0_000169 |
Prestwick1_000169 |
Prestwick2_000169 |
Spectrum2_000969 |
Spectrum3_000455 |
Spectrum4_000005 |
Spectrum5_000822 |
Lopac-H-1753 |
EC-000.1838 |
Epitope ID:137349 |
SCHEMBL7810 |
1(2H)-Phthalazinone, hydrazone, (E)- (9CI) |
NCIOpen2_001484 |
Lopac0_000593 |
Oprea1_207681 |
Oprea1_416878 |
BSPBio_002130 |
KBioGR_000349 |
KBioSS_001355 |
WLN: T66 CNNJ BMZ |
5-25-17-00412 (Beilstein Handbook Reference) |
DivK1c_000117 |
SPBio_000977 |
SPBio_001958 |
CHEMBL276832 |
GTPL7326 |
DTXSID4023129 |
BDBM81461 |
KBio1_000117 |
KBio2_001355 |
KBio2_003923 |
KBio2_006491 |
KBio3_001350 |
RPTUSVTUFVMDQK-UHFFFAOYSA- |
1(2H)-Phthalazinone hydrazone # |
NINDS_000117 |
ALBB-023848 |
NSC_3637 |
8816AB |
NSC126699 |
SBB071765 |
STK246900 |
ZINC12360535 |
Hydralazine; phthalazin-1-ylhydrazine |
AKOS000122609 |
AKOS016843064 |
AKOS028109138 |
CCG-204682 |
DB01275 |
MCULE-9226495081 |
SDCCGSBI-0050575.P005 |
CAS_86-54-4 |
IDI1_000117 |
1-hydrazinylidene-1,2-dihydrophthalazine |
NCGC00015501-01 |
NCGC00015501-03 |
NCGC00015501-04 |
NCGC00015501-05 |
NCGC00015501-06 |
NCGC00015501-07 |
NCGC00015501-17 |
NCGC00162199-01 |
phthalazine, 1-hydrazino-, hydrochloride |
HLZ |
LS-13412 |
(1E)-1-Hydrazono-1,2-dihydrophthalazine |
SBI-0050575.P004 |
FT-0669282 |
ST45026967 |
(1E)-1-hydrazinylidene-1,2-dihydrophthalazine |
C07040 |
D08044 |
48242-EP2272832A1 |
48242-EP2272841A1 |
48242-EP2301936A1 |
48242-EP2311494A1 |
AB00053483_03 |
AB01274815-01 |
AB01274815_02 |
599H497 |
A914301 |
A916276 |
Q419987 |
BRD-K82103381-003-03-7 |
Experimental Data
hydralazine
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 100 | umol/L | 14 | 16 | 14.3 | S | N2 | 29263362 | Active | ||||
| Caenorhabditis elegans | 50 | umol/L | 13 | 15 | 15.38 | S | N2 | 29263362 | Active | ||||
| Caenorhabditis elegans | 100 | umol/L | 15 | 18 | 20 | S | N2 | 29263362 | Active | ||||
| Caenorhabditis elegans | 100 | umol/L | 14 | 16 | 14.38 | S | N2 | 29263362 | Active | ||||
| Caenorhabditis elegans | 10 | umol/L | 14 | 15 | 7 | NS | N2 | 29263362 | Inactive |
Experimental Data Visualization
hydralazine
Statistics Data
hydralazine
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 20 | 1 | 5 |
Statistics Data Visualization
hydralazine
