Compound Summary
Compound Information
haloperidol
Compound Name: | haloperidol |
Compound CID: | 3559 |
Synonyms: | haloperidol 52-86-8 Haldol Serenace Aloperidin More... |
Iupac Name: | 4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one |
InChI: | InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 |
InChIKey: | LNEPOXFFQSENCJ-UHFFFAOYSA-N |
Canonical Smiles: | C1CN(CCC1(C2=CC=C(C=C2)Cl)O)CCCC(=O)C3=CC=C(C=C3)F |
Isomeric Smiles: | C1CN(CCC1(C2=CC=C(C=C2)Cl)O)CCCC(=O)C3=CC=C(C=C3)F |
Molecular Weight: | 375.9 |
Molecular Formula: | C21H23ClFNO2 |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
haloperidol
Molecular Weight: | 375.9 |
Molecular Formula: | C21H23ClFNO2 |
Hydrogen Bond Donor Count: | 1 |
Hydrogen Bond Acceptor Count: | 4 |
Rotatable Bond Count: | 6 |
Heavy Atom Count: | 26 |
Complexity: | 451 |
Synonyms
haloperidol
| haloperidol | haloperidol |
|---|---|
haloperidol |
52-86-8 |
Haldol |
Serenace |
Aloperidin |
Aloperidol |
Brotopon |
Eukystol |
Einalon S |
Aloperidolo |
Galoperidol |
Halojust |
Halopoidol |
Serenase |
Serenelfi |
Ulcolind |
Uliolind |
Halopal |
Linton |
Mixidol |
Pernox |
Sernas |
Sernel |
Dozic |
Aldo |
Lealgin compositum |
Keselan |
Peluces |
Bioperidolo |
4-4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl-1-(4-fluorophenyl)butan-1-one |
McN-JR-1625 |
Haloperidolum |
Aloperidon |
NSC 170973 |
R 1625 |
R-1625 |
1-(3-p-Fluorobenzoylpropyl)-4-p-chlorophenyl-4-hydroxypiperidine |
177716-59-5 |
UNII-J6292F8L3D |
4-(4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl)-1-(4-fluorophenyl)butan-1-one |
Haloperidol (Haldol) |
4-Fluoro-4-(4-(p-chlorophenyl)-4-hydroxypiperidinyl)butyrophenone" |
4-Fluoro-4-(4-hydroxy-4-(4-chlorophenyl)piperidino)butyrophenone |
4-4-(4-Chlorophenyl)-4-hydroxy-1-piperidinyl-1-(4-fluorophenyl)-1-butanone |
CHEMBL54 |
Sigaperidol |
Haldol (TN) |
Haldol Solutab |
4-(4-Hydroxy-4-chloro-4-phenylpiperidino)-4-fluorobutyrophenone |
1-Butanone, 4-4-(4-chlorophenyl)-4-hydroxy-1-piperidinyl-1-(4-fluorophenyl)- |
4-(4-(4-Chlorophenyl)-4-hydroxy-1-piperidinyl)-1-(4-fluorophenyl)-1-butanone |
MLS000028450 |
CHEBI:5613 |
Fortunan |
Halosten |
4-(4-(p-Chlorophenyl)-4-hydroxypiperidino)-4-fluorobutyrophenone" |
4-4-(p-Chlorophenyl)-4-hydroxypiperidino-4-fluorobutyrophenone |
J6292F8L3D |
Butyrophenone, 4-fluoro-4-(4-(p-chlorophenyl)-4-hydroxypiperidino)- |
1-Butanone, 4-(4-(4-chlorophenyl)-4-hydroxy-1-piperidinyl)-1-(4-fluorophenyl)- |
NSC170973 |
NSC615296 |
NSC-170973 |
NSC-615296 |
CAS-52-86-8 |
NCGC00015500-10 |
Aloperidolo DCIT |
Halidol |
Halopidol |
Pekuces |
SMR000058303 |
Halol |
Aloperidolo Italian |
4-4-(4-Chlorophenyl)-4-hydroxypiperidino-4-fluorobutyrophenone" |
Poly2-methoxy-5-(3,7-dimethyloctyloxy)-1,4-phenylenevinylene" |
4-(4-(para-Chlorophenyl)-4-hydroxypiperidino)-4-fluorobutyrophenone" |
Butyrophenone, 4-(4-(p-chlorophenyl)-4-hydroxypiperidino)-4-fluoro- |
gamma-(4-(p-Chlorophenyl)-4-hydroxypiperidino)-p-fluorobutyrophenone |
4-4-(4-chlorophenyl)-4-hydroxy-1-piperidyl-1-(4-fluorophenyl)-butan-1-one |
Poly2-(3,7-dimethyloctyl)oxy-5-methoxy-1,4-phenylene-1,2-ethenediyl |
DSSTox_CID_14150 |
DSSTox_RID_79117 |
DSSTox_GSID_34150 |
Haloperidolum INN-Latin |
Butyrophenone, 4-4-(p-chlorophenyl)-4-hydroxypiperidino-4-fluoro- |
gamma-(4-(p-Chlorophenyl)-4-hydroxpiperidino)-p-fluorbutyrophenone |
CCRIS 1630 |
HSDB 3093 |
SR-01000003076 |
EINECS 200-155-6 |
NSC 615296 |
BRN 0331267 |
Duraperidol |
4-Fluoro-4-4-hydroxy-4-(4-chlorophenyl)piperidinobutyrophenone |
gamma-4-(p-chlorophenyl)-4-hydroxypiperidino-p-fluorobutyrophenone |
4-4-(para-Chlorophenyl)-4-hydroxypiperidino-4-fluorobutyrophenone |
Picroside-III |
Haloperidol, 1 |
Haloperidol, powder |
Prestwick_250 |
n--boc-l-asparagine |
Haloperidol USAN:USP:INN:BAN:JAN |
MDMO-PPV |
Spectrum_000861 |
Tocris-0931 |
Opera_ID_446 |
4-Fluoro-4-(4-hydroxy-4-p-chlorophenylpiperidino)butyrophenone |
4-4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl) |
gamma-(4-(p-Chlorophenyl)-4-hydroxypiperidino)-p-fluorbutyrophenone |
Prestwick0_000115 |
Prestwick1_000115 |
Prestwick2_000115 |
Prestwick3_000115 |
Spectrum2_001268 |
Spectrum3_000448 |
Spectrum4_000570 |
Spectrum5_000788 |
Lopac-H-1512 |
Biomol-NT_000035 |
GTPL86 |
Probes1_000255 |
Probes2_000296 |
H 1512 |
SCHEMBL8264 |
Lopac0_000583 |
Oprea1_509923 |
BSPBio_000130 |
BSPBio_002096 |
KBioGR_000980 |
KBioGR_002390 |
KBioSS_001341 |
KBioSS_002395 |
5-21-02-00377 (Beilstein Handbook Reference) |
MLS001146904 |
BIDD:GT0128 |
DivK1c_000654 |
SPECTRUM1500325 |
Haloperidol-Chlorophenyl-d4 |
SPBio_001236 |
SPBio_002069 |
McM-JR-1625 |
BPBio1_000144 |
BPBio1_001231 |
Haloperidol (JP17/USP/INN) |
DTXSID4034150 |
BDBM21398 |
HMS502A16 |
KBio1_000654 |
KBio2_001341 |
KBio2_002390 |
KBio2_003909 |
KBio2_004958 |
KBio2_006477 |
KBio2_007526 |
KBio3_001316 |
KBio3_002869 |
LNEPOXFFQSENCJ-UHFFFAOYSA- |
AOB5645 |
cMAP_000037 |
NINDS_000654 |
AC250 |
HMS1568G12 |
HMS1920D03 |
HMS2089M15 |
HMS2091J09 |
HMS2095G12 |
HMS2234P08 |
HMS3261F08 |
HMS3370H11 |
HMS3657I13 |
HMS3712G12 |
Pharmakon1600-01500325 |
ZINC537822 |
BCP33202 |
CHA71659 |
Haloperidol 1.0 mg/ml in Methanol |
Tox21_110162 |
Tox21_300475 |
Tox21_500583 |
A0H334 |
CCG-36042 |
CCG-39111 |
MFCD00051423 |
NSC757054 |
STL417208 |
4-4-(4-chlorophenyl)-4-hydroxy-1-piperidyl-1-(4-fluorophenyl)butan-1-one |
AKOS000280660 |
Tox21_110162_1 |
AT13670 |
CS-1971 |
DB00502 |
LP00583 |
MCULE-3693790133 |
NSC-757054 |
SDCCGSBI-0050565.P005 |
IDI1_000654 |
MRF-0000027 |
QTL1_000042 |
WLN: T6NTJ A3VR DF& DQ DR DG |
NCGC00015500-01 |
NCGC00015500-02 |
NCGC00015500-03 |
NCGC00015500-04 |
NCGC00015500-05 |
NCGC00015500-06 |
NCGC00015500-07 |
NCGC00015500-08 |
NCGC00015500-09 |
NCGC00015500-11 |
NCGC00015500-12 |
NCGC00015500-13 |
NCGC00015500-14 |
NCGC00015500-15 |
NCGC00015500-16 |
NCGC00015500-17 |
NCGC00015500-19 |
NCGC00015500-24 |
NCGC00015500-32 |
NCGC00016234-01 |
NCGC00023875-02 |
NCGC00023875-04 |
NCGC00023875-05 |
NCGC00023875-06 |
NCGC00023875-07 |
NCGC00023875-08 |
NCGC00023875-09 |
NCGC00254503-01 |
NCGC00261268-01 |
AC-19691 |
BH166165 |
HY-14538 |
SBI-0050565.P004 |
Haloperidol decanoate impurity, haloperidol- |
SC 170973 |
AB00052008 |
EU-0100583 |
FT-0669100 |
FT-0669101 |
FT-0697842 |
H0912 |
N1910 |
S1920 |
ST50319916 |
SW196557-4 |
W0039 |
4763-EP2269989A1 |
4763-EP2269990A1 |
4763-EP2272537A2 |
4763-EP2272972A1 |
4763-EP2272973A1 |
4763-EP2275420A1 |
4763-EP2277872A1 |
4763-EP2277876A1 |
4763-EP2292614A1 |
4763-EP2295061A1 |
4763-EP2295412A1 |
4763-EP2295413A1 |
4763-EP2295439A1 |
4763-EP2298731A1 |
4763-EP2298776A1 |
4763-EP2305260A1 |
4763-EP2308867A2 |
4763-EP2308870A2 |
4763-EP2311801A1 |
4763-EP2311803A1 |
4763-EP2311824A1 |
4763-EP2311837A1 |
4763-EP2316834A1 |
C01814 |
D00136 |
VU0239704-10 |
AB00052008-21 |
AB00052008-22 |
AB00052008_23 |
AB00052008_24 |
A899749 |
L000288 |
Q251347 |
SR-01000003076-2 |
SR-01000003076-8 |
W-105791 |
BRD-K67783091-001-04-8 |
BRD-K67783091-001-05-5 |
BRD-K67783091-003-03-6 |
SR-01000003076-11 |
Haloperidol, European Pharmacopoeia (EP) Reference Standard |
Poly2-methoxy-5-(3,7-dimethyoctyoxyl)-1,4-phenylenevinylene |
.gamma.-4-(p-Chlorphenyl)-4-hydroxpiperidino-p-fluorbutyrophenone |
Haloperidol, United States Pharmacopeia (USP) Reference Standard |
.gamma.-(4-(p-Chlorophenyl)-4-hydroxpiperidino)-p-fluorbutyrophenone |
4-4-(4-chlorophenyl)-4-hydroxypiperidyl-1-(4-fluorophenyl)butan-1-one |
Haloperidol, Pharmaceutical Secondary Standard; Certified Reference Material |
4-4-(4-Chlorophenyl)-4-hydroxy-1-piperidinyl-1-(4-fluorophenyl) -1-butanone |
Haloperidol for peak identification, European Pharmacopoeia (EP) Reference Standard |
Haloperidol for system suitability, European Pharmacopoeia (EP) Reference Standard |
Haloperidol solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material |
Experimental Data
haloperidol
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 50 | umol/L | 0.92 | NS | N2 | 30970250 | Inactive | ||||||
| Drosophila melanogaster | 200 | umol/L | 47.16 | 49 | 3.9 | NS | MALES | 33008901 | Inactive | ||||
| Caenorhabditis elegans | 33 | umol/L | -8 | NS | N2 | 24134630 | Inactive | ||||||
| Drosophila melanogaster | 20 | umol/L | 52.83 | 57.49 | 8.82 | S | FEMALES | 33008901 | Active |
Experimental Data Visualization
haloperidol
Statistics Data
haloperidol
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Caenorhabditis elegans | 0.92 | 2 | 2 | |
| Drosophila melanogaster | 8.82 | 1 | 2 |
Statistics Data Visualization
haloperidol
