Compound Summary
Compound Information
ha-1004
Compound Name: | ha-1004 |
Compound CID: | 3546 |
Synonyms: | ha-1004 91742-10-8 N-(2-Guanidinoethyl)-5-isoquinolinesulfonamide N-(2-guanidinoethyl)isoquinoline-5-sulfonamide CHEMBL143054 More... |
Iupac Name: | 2-[2-(isoquinolin-5-ylsulfonylamino)ethyl]guanidine |
InChI: | InChI=1S/C12H15N5O2S/c13-12(14)16-6-7-17-20(18,19)11-3-1-2-9-8-15-5-4-10(9)11/h1-5,8,17H,6-7H2,(H4,13,14,16) |
InChIKey: | MZNDNBFMSVMUCX-UHFFFAOYSA-N |
Canonical Smiles: | C1=CC2=C(C=CN=C2)C(=C1)S(=O)(=O)NCCN=C(N)N |
Isomeric Smiles: | C1=CC2=C(C=CN=C2)C(=C1)S(=O)(=O)NCCN=C(N)N |
Molecular Weight: | 293.35 |
Molecular Formula: | C12H15N5O2S |
Compound Structure
2D Structure:
3D Structure:
Computed Properties
ha-1004
Molecular Weight: | 293.35 |
Molecular Formula: | C12H15N5O2S |
Hydrogen Bond Donor Count: | 3 |
Hydrogen Bond Acceptor Count: | 5 |
Rotatable Bond Count: | 5 |
Heavy Atom Count: | 20 |
Complexity: | 441 |
Synonyms
ha-1004
| ha-1004 | ha-1004 |
|---|---|
ha-1004 |
91742-10-8 |
N-(2-Guanidinoethyl)-5-isoquinolinesulfonamide |
N-(2-guanidinoethyl)isoquinoline-5-sulfonamide |
CHEMBL143054 |
H-1004 |
HA1004 |
2-2-(5-isoquinolinylsulfonylamino)ethylguanidine |
Amino{2-(5-isoquinolylsulfonyl)aminoethyl}carboxamidine |
HA 1004 |
HT 1004 |
KBioGR_000453 |
n-(2-carbamimidamidoethyl)isoquinoline-5-sulfonamide |
N-(2-((Aminoiminomethyl)amino)ethyl)-5-isoquinolinesulfonamide |
BiomolKI_000037 |
BiomolKI2_000045 |
BSPBio_001113 |
KBioSS_000453 |
SCHEMBL1272417 |
CHEBI:92097 |
KBio2_000453 |
KBio2_003021 |
KBio2_005589 |
KBio3_000845 |
KBio3_000846 |
BRD4375 |
DTXSID60919543 |
BDBM492910 |
Bio2_000387 |
Bio2_000867 |
HMS1362G15 |
HMS1792G15 |
HMS1990G15 |
HMS3403G15 |
5-Isoquinolinesulfonamide, N-(2-((aminoiminomethyl)amino)ethyl)- |
BRD-4375 |
ZINC2170223 |
BDBM50216680 |
AKOS024285644 |
CCG-100641 |
IDI1_002142 |
NCGC00163379-01 |
NCGC00163379-02 |
NCGC00163379-03 |
ST086170 |
US10981896, Compound HA-1004 |
1-(2-(isoquinoline-5-sulfonamido)ethyl)guanidine |
1-2-(5-isoquinolylsulfonylamino)ethylguanidine |
BRD-K05434375-001-03-2 |
BRD-K05434375-001-04-0 |
Q27163889 |
Experimental Data
ha-1004
| Species | Dosage | Unit | CG Lifespan(AVG/MED days) | TG Lifespan(AVG/MED days) | Lifespan Change(AVG/MED%) | CG Lifespan(MAX days) | TG Lifespan(MAX days) | Lifespan Change(MAX%) | Significant | Strain | Gender | PubMed | Active Label |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Drosophila melanogaster | 18 | S | Oregon-R | 22363408 | Active |
Experimental Data Visualization
ha-1004
Statistics Data
ha-1004
| Species | Lifespan Change(AVG/MED%) | Lifespan Change(MAX%) | Count Reference | Count Data point |
|---|---|---|---|---|
| Drosophila melanogaster | 18 | 1 | 1 |
Statistics Data Visualization
ha-1004
